4-Hydroxy Valsartan, Mixture of Diastereomers

4-Hydroxy Valsartan, Mixture of Diastereomers Structure
CAS No.
188259-69-0
Chemical Name:
4-Hydroxy Valsartan, Mixture of Diastereomers
Synonyms
CGP 71580;Valsartan 4-Hydroxy;Valsartan Impurity I;Valsartan 4-Hydroxy Impurity;Valsartan related compound I;(2S)-2-(N-((2'-(1H-tetrazol-5-yl);Valsartan 4-Hydroxy Valeryl Analog;4-Hydroxy Valsartan, Mixture of Diastereomers;N-(4-Hydroxy-1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl) [1,1'-biphenyl]-4-yl]Methyl]-;N-(4-Hydroxy-1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine
CBNumber:
CB11175870
Molecular Formula:
C24H29N5O4
Molecular Weight:
451.52
MOL File:
188259-69-0.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:12

4-Hydroxy Valsartan, Mixture of Diastereomers Properties

Melting point 130-132°C
storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility Methanol (Slightly)
form Solid
color White to Off-White
Stability Hygroscopic
CAS DataBase Reference 188259-69-0

4-Hydroxy Valsartan, Mixture of Diastereomers Chemical Properties,Uses,Production

Description

4-hydroxy Valsartan is a major metabolite of the angiotensin II type 1 (AT1) receptor antagonist valsartan . It reduces platelet aggregation induced by epinephrine and collagen but not ADP in human whole blood.

Chemical Properties

White Solid

4-Hydroxy Valsartan, Mixture of Diastereomers Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-2-{(4(R,S)-Hydroxy-pentanoyl)-[2(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]amino}-3-methyl-butyric Acid 4-Hydroxy Valsartan, Mixture of Diastereomers CGP 71580 N-(4-Hydroxy-1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Valsartan 4-Hydroxy N-(4-Hydroxy-1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl) [1,1'-biphenyl]-4-yl]Methyl]- Valsartan related compound I (S)-N-(4-Hydroxy-1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-valine (2S)-2-(N-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-4-hydroxypentanamido)-3-methylbutanoic acid Valsartan 4-Hydroxy Impurity Valsartan 4-Hydroxy Valeryl Analog (2S)-2-[4-hydroxypentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-3-methylbutanoic acid (2S)-2-(N-((2'-(1H-tetrazol-5-yl) L-Valine, N-(4-hydroxy-1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- 4-hydroxy valsartanQ: What is 4-hydroxy valsartan Q: What is the CAS Number of 4-hydroxy valsartan Q: What is the storage condition of 4-hydroxy valsartan Q: What are the applications of 4-hydroxy valsartan Valsartan Impurity I 188259-69-0 Intermediates & Fine Chemicals Metabolites Pharmaceuticals