Esterastin

Esterastin Structure
CAS No.
67655-93-0
Chemical Name:
Esterastin
Synonyms
Esterastin;Esterastin DISCONTINUED;L-Asparagine, N2-acetyl-, (1S,3Z,6Z)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]-3,6-dodecadien-1-yl ester
CBNumber:
CB11178644
Molecular Formula:
C28H46N2O6
Molecular Weight:
506.67
MOL File:
67655-93-0.mol

Esterastin Properties

storage temp. Amber Vial, -20°C Freezer, Under inert atmosphere

Esterastin Chemical Properties,Uses,Production

Uses

Esterastin is a potent inhibitor of lysosomal acid lipase. Esterastin inhibited the enzyme activity very strongly (IC50, about 80 nM). The inhibition of acid lipase by Esterastin was competitive with respect to the substrate and the inhibition constant for Esterastin was 90 nM. Esterastin was less inhibitory to other lipolytic enzymes, such as pancreatic lipase and carboxylesterase. Thus, Esterastin is a potent new inhibitor of lysosomal acid lipase.

Esterastin Preparation Products And Raw materials

Raw materials

Preparation Products

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67655-93-0(Esterastin)Related Search:

Esterastin L-Asparagine, N2-acetyl-, (1S,3Z,6Z)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]-3,6-dodecadien-1-yl ester Esterastin DISCONTINUED 67655-93-0 Amino Acids & Derivatives Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals