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SCE 2174

SCE 2174 Structure
CAS No.
95789-30-3
Chemical Name:
SCE 2174
Synonyms
SCE 2174;Cefotiam Imp;SCE 2174 USP/EP/BP;Cefotiam Impurity 15;CTM-HE hydrochloride;Cefotiam Hexetil 2HCl;SCE-2174 hydrochloride;cefotiam hexetil dihydrochloride;Cefotiam (mixture of Diastereomers);Cefotiam Impurity 11(Cefotiam Hexetil Hydrochloride)
CBNumber:
CB11270102
Molecular Formula:
C27H38ClN9O7S3
Molecular Weight:
732.29
MOL File:
95789-30-3.mol
Modify Date:
2023/5/4 15:13:20

SCE 2174 Properties

Melting point 120-130°C
storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Pale Yellow
CAS DataBase Reference 95789-30-3

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H334-H317
Precautionary statements  P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P261-P285-P304+P341-P342+P311-P501
Toxicity LD50 in male, female mice, male, female rats (mg/kg): 1290, 1150, 1470, 1620 i.p.; >2000 s.c.; >5000 orally (Chiba)

SCE 2174 Chemical Properties,Uses,Production

Description

Cefotiam hexetil hydrochloride is an orally active, broad-spectrum cephalosporin useful in the treatment of bacterial infections. It is a prodrug hydrolyzed in the GI tract and absorbed as cefotiam. Cefotiam hexetil hydrochloride is reported to be especially potent against Streptococci strains.

Chemical Properties

Off-White to Pale Yellow Solid

Uses

A semi-synthetic cephalosporin antibiotic. Antibacterial.

Definition

ChEBI: The dihydrochloride salt of cefotiam 1-(cyclohexyloxycarbonyloxy)ethyl ester. It is used as a prodrug for cefotiam.

SCE 2174 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 73)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21670 55 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-89586680 +86-18192503167 China 9030 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418684 +8618949823763 China 25363 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
PT CHEM GROUP LIMITED +86-85511178 +86-85511178 China 35451 58 Inquiry
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-, 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester, dihydrochloride, (6R,7R)- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-, 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester, dihydrochloride, [6R-(6α,7β)]- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[2-(2-aMino-4-thiazolyl)acetyl]aMino]-3-[[[1-[2-(diMethylaMino)ethyl]-1H-tetrazol-5-yl]thio]Methyl]-8-oxo-, 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester, hydrochloride (1:2), (6R,7R)- SCE 2174 1-cyclohexyloxycarbonyloxyethyl (6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-3-[[1-(2-dimethylaminoethyl)tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate dihydrochloride (6R-(6-alpha,7-beta))-7-(((2-Amino-4-thiazolyl)acetyl)amino)-3-(((1-(2-(dimethylamino)ethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 1-(((cyclohexyloxy)carbonyl)oxy)ethyl ester dihydrochloride Cefotiam (mixture of Diastereomers) Cefotiam Hexetil 2HCl cefotiam hexetil dihydrochloride 1-(Cyclohexyloxycarbonyloxy)ethyl ester dihydrochloride Cefotiam Impurity 15 Cefotiam Hexetil Hydrochloride (mixture of Diastereomers) Cefotiam Imp SCE 2174 USP/EP/BP Cefotiam Hexetil Hydrochloride,CTM-HE,Inhibitor,Antibiotic,Bacterial,SCE2174,Cefotiam hexetil,SCE-2174,SCE 2174,inhibit Cefotiam Impurity 11(Cefotiam Hexetil Hydrochloride) CTM-HE hydrochloride SCE-2174 hydrochloride 95789-30-3 C27H39Cl2N9O7S3 C27H37N9O7S32HCl C27H37N9O7S32ClH Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds