Azoles

CAS No.: 421581-70-6

Chemical Name:: Azoles

Synonyms: Azoles;2-Acetyl-7-methylbenzofuran;1-(7-Bromobenzofuran-2-yl)ethanone;5-Ethyl-3-p-tolyl-1,2,4-oxadiazole;5-Methyl-3-p-tolyl-1,2,4-oxadiazole;5-Propyl-3-p-tolyl-1,2,4-oxadiazole;5-Methyl-3-(p-tolyl)-1,2,4-oxadiazole;5-Propyl-3-(p-tolyl)-1,2,4-oxadiazole;5-Cyclohexyl-3-p-tolyl-1,2,4-oxadiazole;5-tert-Butyl-3-p-tolyl-1,2,4-oxadiazole

CBNumber:: CB11326926

Molecular Formula:: C14H8FN3O3

Molecular Weight:: 285.23

MOL File:: 421581-70-6.mol

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Azoles Properties

Boiling point	446.8±55.0 °C(Predicted)
Density	1.389±0.06 g/cm3(Predicted)
storage temp.	2-8°C
pka	-2.78±0.37(Predicted)
CAS DataBase Reference	421581-70-6

Azoles Chemical Properties,Uses,Production

Pharmaceutical Applications

A large group of synthetic agents, which includes drugs used in bacterial and parasitic infections (5-nitroimidazoles; benzimidazoles). Antifungal azoles have in common an imidazole or triazole ring with N-carbon substitution. The activity is essentially fungistatic, but some of the newer triazoles exert fungicidal effects at therapeutic concentrations. They are effective in the topical treatment of dermatophytoses and superficial forms of candidosis; several are suitable for systemic administration.
Several molecular mechanisms of resistance have been elucidated. These include overexpression of efflux pump genes, point mutations in the gene that encodes the target enzyme, lanosterol demethylase, and overexpression of this gene. Changes in other enzymes involved in ergosterol biosynthesis, such as sterol desaturase, may also contribute to azole resistance.

Azoles Preparation Products And Raw materials

Raw materials

Preparation Products

Azoles Suppliers

Global( 22)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6707	30	Inquiry
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	China	30250	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58	Inquiry
Amadis Chemical Company Limited	571-89925085	China	131980	58	Inquiry
Shanghai Haohong Scientific Co., Ltd.	400-400-8210725	China	39990	58	Inquiry
Combi-Blocks Inc.	858 635 8950	United States	6632	69	Inquiry
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-66099280 17798518460	China	19918	55	Inquiry
NE Scientific	+1 (617) 651-6662	United States	5031	55	Inquiry

Supplier	Advantage
A.J Chemicals	58
CLEARSYNTH LABS LTD.	58
CHEMSWORTH	30
Career Henan Chemica Co	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
Shanghai Haohong Scientific Co., Ltd.	58
Combi-Blocks Inc.	69
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	55
NE Scientific	55

421581-70-6(Azoles)Related Search:

3-(5-METHYL-1,2,4-OXADIAZOL-3-YL)ANILINE 5-ETHYL-3-P-TOLYL-1,2,4-OXADIAZOLE 5-(4-Fluoro-phenyl)-3-methyl-[1,2,4]oxadiazole 3-(3-NITROPHENYL)-1,2,4-OXADIAZOLE 3-(3-NITROPHENYL)-5-METHYL OXADIAZOLE

3-(3-NITROPHENYL)-5-PHENYL-1,2,4-OXADIAZOLE Azoles 2-(3-Bromophenyl)-5-methyl-1,3,4-oxadiazole

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Azoles 2-(3-Bromophenyl)-5-(trichloromethyl)-1,3,4-oxadiazole 2-(3-Bromophenyl)-5-trichloromethyl-1,3,4-oxadiazole 1-(7-Bromobenzofuran-2-yl)ethanone 2-Acetyl-7-methylbenzofuran 3-(3-Nitrophenyl)-5-phenyl-1,2,4-oxadiazole 3-(4-Bromophenyl)-5-cyclohexyl-1,2,4-oxadiazole 5-(2-Chlorophenyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole 5-(4-Fluorophenyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole 5-Cyclohexyl-3-(p-tolyl)-1,2,4-oxadiazole 5-Cyclohexyl-3-p-tolyl-1,2,4-oxadiazole 5-Ethyl-3-(4-nitrophenyl)-1,2,4-oxadiazole 5-Ethyl-3-p-tolyl-1,2,4-oxadiazole 5-Methyl-3-(p-tolyl)-1,2,4-oxadiazole 5-Methyl-3-p-tolyl-1,2,4-oxadiazole 5-Propyl-3-(p-tolyl)-1,2,4-oxadiazole 5-Propyl-3-p-tolyl-1,2,4-oxadiazole 5-tert-Butyl-3-p-tolyl-1,2,4-oxadiazole 1,2,4-Oxadiazole, 5-(4-fluorophenyl)-3-(3-nitrophenyl)- 421581-70-6 C9H6BrClN2O C14H8FN3O3 C9H4BrCl3N2O FluoroCompounds NitroCompounds Azoles blocks Bromides