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ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >Other Amino Acid Protection >HBTU

HBTU

HBTU Structure
CAS No.
94790-37-1
Chemical Name:
HBTU
Synonyms
1-[Bis(dimethylamino)methylene]-1H-benzotriazolium hexafluorophosphate(1-) 3-oxide;O-benzotriazol-l-yl-tetramethyluroniumhexafluorophosphate;O-BENZOTRIAZOL-1-YL-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE;O-(BENZOTRIAZOL-1-YL)-N,N,N',N'-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE;2-(1H-BENZOTRIAZOLE-1-YL)-1,1,3,3-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE;O-(1H-BENZOTRIAZOL-1-YL)-N,N,N',N'-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE;HBTU;-1-yL;HBTU,99%;HBTU 25 G
CBNumber:
CB1138465
Molecular Formula:
C11H16F6N5OP
Molecular Weight:
379.25
MOL File:
94790-37-1.mol
MSDS File:
SDS
Modify Date:
2024/6/6 17:55:34
Request For Quotation

HBTU Properties

Melting point 200 °C (dec.)(lit.)
Flash point 200°C
storage temp. Store at +2°C to +8°C.
solubility acetonitrile: 0.1 g/mL, clear
form Powder
color White to Off-White
PH 4.1 (1.6g/l, H2O)
Decomposition 200 ºC
BRN 7328329
Stability Stable. Incompatible with oxidizing agents.
InChI InChI=1S/C11H16N5O.F6P/c1-13(2)11(14(3)4)15-9-7-5-6-8-10(9)16(17)12-15;1-7(2,3,4,5)6/h5-8H,1-4H3;/q+1;-1
InChIKey UQYZFNUUOSSNKT-UHFFFAOYSA-N
SMILES [P+5]([F-])([F-])([F-])([F-])([F-])[F-].C(=[N+]1/N=N(=O)C2=CC=CC=C/12)(\N(C)C)/N(C)C
CAS DataBase Reference 94790-37-1(CAS DataBase Reference)
EPA Substance Registry System 1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, 3-oxide, hexafluorophosphate(1-) (1:1) (94790-37-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H317-H335
Precautionary statements  P261-P264-P271-P272-P280-P302+P352
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22-42/43
Safety Statements  26-36/37/39-36-22
WGK Germany  3
F  8-10-21
Hazard Note  Irritant
HS Code  29339980
Toxicity LD50 orally in Rabbit: > 2000 mg/kg
NFPA 704
1
2 0

HBTU price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 8.51006 HBTU 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate Novabiochem? 94790-37-1 25G ₹4979.99 2022-06-14 Buy
Sigma-Aldrich(India) 8.51006 HBTU 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate Novabiochem? 94790-37-1 100G ₹11940 2022-06-14 Buy
Sigma-Aldrich(India) 8.51006 HBTU 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate Novabiochem? 94790-37-1 1KG ₹26610.01 2022-06-14 Buy
Sigma-Aldrich(India) 8.51006 HBTU 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate Novabiochem? 94790-37-1 8510062500 ₹66710 2022-06-14 Buy
Sigma-Aldrich(India) 12804 HBTU ≥98.0% (T) 94790-37-1 1G ₹2381.5 2022-06-14 Buy
Product number Packaging Price Buy
8.51006 25G ₹4979.99 Buy
8.51006 100G ₹11940 Buy
8.51006 1KG ₹26610.01 Buy
8.51006 8510062500 ₹66710 Buy
12804 1G ₹2381.5 Buy

HBTU Chemical Properties,Uses,Production

Chemical Properties

white to light yellow powder

Uses

HBTU is a coupling reagent used in peptide synthesis. HBTU has been shown to effectively suppress racemization.

Purification Methods

Wash the salt with H2O (3x), CH2Cl2 (3x), dry and recrystallise it from MeCN. Dry it in a vacuum and store it cold in the dark [Dourtoglou et al. Tetrahedron Lett 1269 1978, NMR: Dourtoglou and Gross Synthesis 572 1984]. Benzoxazolinone (2 -hydroxybenzoxazole) [59 -49 -4] M 135.1, m 137 -139o, 142 -143o(corrected), b 121-213o/17mm, 335-337o/760mm. Benzoxazolinone is purified by recrystallisation from aqueous Me2CO followed by distillation at atmospheric pressure, then in a vacuum. The methyl mercury salt recrystallises from aqueous EtOH and has m 156-158o. [Bywater et al. J Am Chem Soc 67 905 1945, Beilstein 27 III/IV 2677.]

HBTU Preparation Products And Raw materials

Raw materials

Preparation Products

Methanone, (3,3-difluoro-1-azetidinyl)[8,9-dihydro-9-methoxy-2,3-dimethyl-9-(2-methylphenyl)-7H-imidazo[1,2-a]pyrano[2,3-c]pyridin-6-yl]-

HBTU Suppliers

Global( 574)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
BTC pharm India +918790379245 AndhraPradesh, India 1269 58 Inquiry
Litha Life Sciences Pvt Limited +91-9849999500 +91-9849999500 Hyderabad, India 29 58 Inquiry
JIVICHEM SYNTHESIS PVT LTD +91-7028392790 +91-7028392790 Maharashtra, India 337 58 Inquiry
NSJ Prayog Life Sciences Private Limited +91-6281747900 +91-6281747900 Hyderabad, India 76 58 Inquiry
Vardhaman P Golechha 9704422000 Telangana, India 294 58 Inquiry
MTS LABORATORIES +91-9502850231 +91-9618305753 Telangana, India 47 58 Inquiry
Aavish Drugs Pvt Ltd +919849535891 Hyderabad, India 5 58 Inquiry
SYNGENESIS CHEMSCIENCE PRIVATE LIMITED +91-9067779401 +91-9067779401 Maharashtra, India 58 58 Inquiry
JSK Chemicals +919879767970 Gujarat, India 3756 58 Inquiry
SVK Laboratories Pvt Ltd +91-40-23095079 +91-9177729915 Telangana, India 89 58 Inquiry
Supplier Advantage
BTC pharm India 58
Litha Life Sciences Pvt Limited 58
JIVICHEM SYNTHESIS PVT LTD 58
NSJ Prayog Life Sciences Private Limited 58
Vardhaman P Golechha 58
MTS LABORATORIES 58
Aavish Drugs Pvt Ltd 58
SYNGENESIS CHEMSCIENCE PRIVATE LIMITED 58
JSK Chemicals 58
SVK Laboratories Pvt Ltd 58

Related Qustion

HBTU Spectrum

HBTU(94790-37-1)1HNMRHBTU(94790-37-1)FT-IR

94790-37-1(HBTU)Related Search:

2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate HOAt 1-Hydroxybenzotriazole HATU Hexafluorophosphoric acid
Potassium hexafluorophosphate 5-Methyl-1H-benzotriazole Tolyltriazole Lithium hexafluorophosphate Sodium hexafluorophosphate
1H-Benzotriazole 2-(7-Azabenzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate 3-Hydroxy-1,2,3-benzotriazin-4(3H)-one 1-Hydroxybenzotriazole hydrate Ammonium hexafluorophosphate
5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate (Benzotriazol-1-yloxy)dipyrrolidinocarbenium hexafluorophosphate HBTU
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O-(BENZOTRIAZOL-1-YL)-N-N-N ,N -TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE O-BENZOTRIAZOL-1-YL-N,N,N',N'-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE POLYMER BOUND O-BENZOTRIAZOLE-1-YL-N,N,N',N'-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE O-BENZOTRIAZOLE-N,N,N',N'-TETRAMETHYL-URONIUM O-BENZOTRIAZOLE-N,N,N',N'-TETRAMETHYL-URONIUM-HEXAFLUORO-PHOSPHATE O-BENZOTRIAZOLE-N,N,N',N'-TETRAMTHYL-URONIUM-HEXAFLUORO-PHOSPHATE N-[(1-H-BENZOTRIAZOL-1-YL)(DIMETHYLAMINO)METHYLENE]-N-METHYLMETHANAMINIUM HEXAFLUOROPHOSPHATE N-OXIDE O-(1H-benzotriazol-1-y1)-N,N,N'N'-tetramethyluronium Hexafluorophosphate(HBTU) O-BENZOTRIAZOL-1-YL-TETRAMETHYLURONIUM (HBTU ) HBTU (O-(BENZOTRIAZOL-1-YL)-N,N,N'',N''-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE) O-(Benzotriazole-N,N,N'',N''-tetramethyluronium hexafluorophosphate (HBTU) O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium Hexafluorophosphate [Coupling Reagent for Peptide] benzotriazolyl tetramethyluronium fluorophosphate HBTU, N,N,Nμ,Nμ-Tetramethyl-O-(1H-benzotriazol-1-yl)uronium hexafluorophosphate (Benzotriazol-1-yloxy-dimethylaminomethylidene)-dimethylazanium hexafluorophosphate O-Benzotriazolyl-N,N,N',N'-tetramethyluronium hexafluorophosphate o-Benzotriazole-N,N,N',N'-tetramethyl-uronium-hexafluorophosphate ,99% HBTU (o-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexaflu HBTU,2 bottles kit, 0.1M in HOBT/DMF (0.5M HOBT in DMF) HBTU,99% O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate≥ 99% (HPLC) O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate BENZOTRIAZOL-1-YL-N,N,N',N'-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE HBTU HBTU POLYMER BOUND HBTU-REAGENT HEXAFLUOROPHOSPHATE HBTU 2-(1H-BENZOTRIAZOL-1-YL)-1,1,3,3-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE 2-(1H-BENZOTRIAZOL-1-YL)-1,1,3,3-TETRAMETHYLURONOIUM HEXAFLUORPHOSPHATE 1-[BIS(DIMETHYLAMINO)METHYLENE]-1H-BENZOTRIAZOLIUM 3-OXIDE HEXAFLUOROPHOSPHATE O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexaflorophosphate HBTU [O-BENZOTRIAZOLE-N,N,N',N'-TETRAMETHYL-URONIUM-HEXAFLUORO-PHOSPHATE] O-Benzotriazol-1-yl-tetramethyluronium 2-(1H-BENZOTRIAZOLE-1-YL)-1,1,3,3-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE (HBTU) HBTU, 3 bottles, 0.1M in HOBT/DMF (0.45M HOBT in DMF)1:1 1H-Benzotriazolium, 1-bis(dimethylamino)methylene-, hexafluorophosphate(1-), 3-oxide 2-(1H-BENZOTRIAZOL-1-YL)-1,1,3,3-TETRAMETHYLURONIUMHEXAFLUOROPHOSPHATE(HBTU) ORTHOBENZOTRIAZOLE1YLNNNNTETRAMETHYLURONIUMHEXAFLUOROPHOSPHATE HBTU [O-Benzotriazole-N N'-tetraMethyl-uroniuM-hexafluoro-phosphate] HBTU (o-(Benzotriazol-1-yl)-N,N,Nzzhlxy,Nzzhlxy-tetramethyluronium hexafluorophosphate) HBTU 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetraMethyluroniuM hexafluorophosphate O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate,N,N,N′,N′-Tetramethyl-O-(1H-benzotriazol-1-yl)uronium hexafluorophosphate, HBTU O-Benzotriazole-N,N HBTU N,N,N',N'-Tetramethyl-O-(benzotriazol-1-yl)uronium Hexafluorophosphate N,N,N',N'-TETRAMETHYL-O-(1H-BENZOTRIAZOL-1-YL)URONIUM HEXAFLUOROPHOSPHATE N,N,N',N'-TETRAMETHYL-O-(BENZOTRIAZOL-1-YL)URONIUM HEXAFLUOROPHOSPHATE O-(1H-BENZOTRIAZOL-1-YL)-1,1,3,3-TETRAMETHYL-URONIUM HEXAFLUOROPHOSPHATE HBTU, [(1H-Benzotriazol-1-yl)oxy](dimethylamino)-N,N-dimethylmethaniminium hexafluorophosphate O-(1H-Benzotriazole-1-yl)-N,N,N,N-tetD23-RAMethyluroniuM Hexafluorophosphate HBTU >=98.0% (T) HBTU For Synthesis HBTU extrapure, 98% [benzotriazol-1-yloxy(dimethylamino)methylidene]-dimethylazanium 0-benzotriazol-1-yl-n,n, n',n'-tetramethyluronium 1-[Bis(dimethylamino)methylene]-1H-benzotriazolium hexafluorophosphate(1-) 3-oxide（HBTU） HATU [ 148893-10-1 HBTU USP/EP/BP