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perlapine

perlapine Structure
CAS No.
1977-11-3
Chemical Name:
perlapine
Synonyms
HF 2333;Hypnodin;AW 14-2333;6-(4-Methyl-1-piperazinyl)-11H-dibenz[b,e]azepin;6-(4-Methyl-1-piperazinyl)-11H-dibenz[b,e]azepine;11H-Dibenz[b,e]azepine, 6-(4-methyl-1-piperazinyl)-;6-(4-methylpiperazin-1-yl)-11H-benzo[c][1]benzazepine
CBNumber:
CB11388928
Molecular Formula:
C19H21N3
Molecular Weight:
291.39
MOL File:
1977-11-3.mol
Modify Date:
2023/6/30 15:45:59
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perlapine Properties

Melting point 136-138°
Boiling point 423.4°C (rough estimate)
Density 1.0521 (rough estimate)
refractive index 1.6080 (estimate)
storage temp. Store at -20°C
solubility DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 5 mg/ml
form A crystalline solid
pka 8.00±0.20(Predicted)
color White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Toxicity LD50 in male, female mice, rats (mg/kg): 61, 61, 60, 66 i.v.; 250, 300, 480, 420 s.c., 270, 280, 660, 720 orally (Yokotani)
NFPA 704
0
2 0

perlapine Chemical Properties,Uses,Production

Uses

Perlapine is an atypical neuroleptic that blocks dopamine and serotonin (5-HT) receptors (Kis = 60, 30, and 30 nM for D2, D4, and 5-HT2A, respectively). Perlapine is also an agonist for hM3Dq, a designer receptor exclusively activated by designer drugs (DREADD) derived from the human muscarinic acetylcholine M3 receptor that activates neuronal firing. Perlapine displays >10,000-fold selectivity for hM3Dq over hM3.

perlapine Preparation Products And Raw materials

Raw materials

Preparation Products

perlapine Suppliers

Global( 12)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
RD International Technology Co., Limited 18024082417 China 9155 58 Inquiry
Shanghai New Union Textra Import & Export Co., Ltd +861-348-227-9455 China 2752 60 Inquiry
CHEMICAL LAND21 82- 2 -783 - 8063 South Korea 6315 74 Inquiry
Tocris Bioscience +44 (0) 117 916 3333 United Kingdom 5729 77 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
Energy Chemical 021-58432009 400-005-6266 China 44843 58 Inquiry
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 China 11289 58 Inquiry
Supplier Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd. 58
TargetMol Chemicals Inc. 58
Cayman Chemical Company 81
RD International Technology Co., Limited 58
Shanghai New Union Textra Import & Export Co., Ltd 60
CHEMICAL LAND21 74
Tocris Bioscience 77
Shanghai Hao Zhun Biological Technology Co., Ltd. 58
Energy Chemical 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58

1977-11-3(perlapine)Related Search:

FLUPERLAPINE 2-ETHYL-BENZAMIDINE perlapine 1-(2-METHYLBENZYL)PIPERAZINE
6-(4-Methyl-1-piperazinyl)-11H-dibenz[b,e]azepin AW 14-2333 HF 2333 Hypnodin 6-(4-methylpiperazin-1-yl)-11H-benzo[c][1]benzazepine 6-(4-Methyl-1-piperazinyl)-11H-dibenz[b,e]azepine 11H-Dibenz[b,e]azepine, 6-(4-methyl-1-piperazinyl)- 1977-11-3