SR 48692
- CAS No.
- 146362-70-1
- Chemical Name:
- SR 48692
- Synonyms
- Meclinertant;2-CARBOXYLIC ACID;CS-334;SR 48692;merclinertant;meclinertant, CID 119192;2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]adamantane-2-carboxylic acid;2-[[[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]tricyclo[3.3.1.13,7]decane-2-carboxylic acid;Tricyclo[3.3.1.13,7]decane-2-carboxylic acid, 2-[[[1-(7-chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]-
- CBNumber:
- CB11396891
- Molecular Formula:
- C32H31ClN4O5
- Molecular Weight:
- 587.07
- MOL File:
- 146362-70-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/3/27 13:09:27
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| WGK Germany | 3 |
| RTECS | YD1988500 |
SR 48692 price More Price(2)
SR 48692 Chemical Properties,Uses,Production
Uses
SR 48692 has been used as a neurotensin?high-affinity receptor 1 (NTSR1) antagonist:
- to explore the function of NTSR1 in glioblastoma (GBM) cells
- to determine the roles of neurotensin (NT) in the regulation of bile acid?(BA) uptake, in vivo
- to explore the involvement of NTSR1 versus NTSR2 in mice
Biochem/physiol Actions
SR 48692 is a high affinity, orally bioavailable and selective nonpeptide NT1 neurotensin receptor antagonist that antagonizes neurotensin-induced calcium mobilization with a pA2 of 8.13 in HT-29 human colon carcinoma cell line, and blocks the ability of neurotensin to increase GABA levels in the prefrontal cortex.
SR 48692 Preparation Products And Raw materials
Raw materials
Preparation Products
SR 48692 Suppliers
Global( 54)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Shaanxi Franta Biotechnology Co., Ltd | +86-13082019107 +86-13082019107 | China | 225 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | China | 33350 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
| Amadis Chemical Company Limited | 571-89925085 | China | 131980 | 58 | Inquiry |
| Shanghai Hao Zhun Biological Technology Co., Ltd. | 15800340161 | CHINA | 6846 | 58 | Inquiry |
| Absin Bioscience Inc. | 021-38015121 | CHINA | 6661 | 58 | Inquiry |
| Qingdao Jieshikang Biotechnology Co., Ltd. | 4009025885 18754289606 | CHINA | 4012 | 58 | Inquiry |
| Qiyi Biotechnology (Shanghai) Co., Ltd. | 021-60348496 18121453965 | CHINA | 6105 | 58 | Inquiry |
| Beijing Taize Jiaye Technology Development Co., Ltd. | 400-800-8151 | CHINA | 6050 | 58 | Inquiry |
146362-70-1(SR 48692)Related Search:
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SR 48692
2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]adamantane-2-carboxylic acid
2-[[[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]tricyclo[3.3.1.13,7]decane-2-carboxylic acid
meclinertant, CID 119192
merclinertant
CS-334
Tricyclo[3.3.1.13,7]decane-2-carboxylic acid, 2-[[[1-(7-chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]-
2-CARBOXYLIC ACID
Meclinertant
146362-70-1