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OROTIDINE

OROTIDINE Structure
CAS No.
314-50-1
Chemical Name:
OROTIDINE
Synonyms
OROTIDINE;Orotidine ,98%;6-Carboxyuridine;URIDIN-6-CARBOXYLIC ACID;URIDINE-6-CARBOXYLIC ACID;orotidine free acid approx. 90%;Orotidine (Uridine-6-carboxylic acid);1,2,3,6-Tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-4-pyrimidinecarboxylic acid;4-Pyrimidinecarboxylicacid, 1,2,3,6-tetrahydro-2,6-dioxo-3-b-D-ribofuranosyl-;4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-
CBNumber:
CB1164936
Molecular Formula:
C10H12N2O8
Molecular Weight:
288.21
MOL File:
314-50-1.mol
Modify Date:
2024/5/21 17:15:21
Request For Quotation

OROTIDINE Properties

Melting point >400 °C
Density 1.847±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form Solid
pka 2.62±0.20(Predicted)
color White to Off-White

SAFETY

Risk and Safety Statements

WGK Germany  3
HS Code  29349990

OROTIDINE Chemical Properties,Uses,Production

Uses

Orotidine is a metabolite of Orotic Acid (O691500); a compound used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment.

Definition

ChEBI: A nucleoside formed by attaching orotic acid to a ribose ring via a beta1N(1)-glycosidic bond.

Enzyme inhibitor

This water-soluble ribonucleoside (FWfree-acid = 288.21 g/mol; CAS 314-50- 1; lmax of 267 nm in 0.1 N HCl (e = 9570 cm–1M–1; another report lists 9800) and 265 nm in 0.1 N methanolic NaOH (e = 8960 cm–1M–1; another report lists 7800)), first observed in Neurospora crassa, is also foound in the urine of cancer patients treated with 6-azauridine, Orotidine is most likely formed from OMP, its 5’-monophosphate ester and the direct precursor of UMP. Orotidine is readily hydrolyzed in dilute mineral acids. Target(s): orotate phosphoribosyltransferase; orotidine-5’-phosphate decarboxylase.

OROTIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

OROTIDINE Suppliers

Global( 47)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-81138252 +86-18789408387 China 3406 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21669 55 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
NewCan Biotech Limited +86-0571-86912261 +8613735419629 China 9980 58 Inquiry
Henan Alfa Chemical Co., Ltd +8618339805032 China 13187 58 Inquiry
GIHI CHEMICALS CO.,LIMITED +8618058761490 China 49999 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Shanghai Hao Biological Technology Co., Ltd. 021-58116080 18019263206 CHINA 6921 58 Inquiry
Supplier Advantage
CHEMSWORTH 30
Shaanxi Dideu Medichem Co. Ltd 58
Henan Tianfu Chemical Co.,Ltd. 55
BOC Sciences 58
NewCan Biotech Limited 58
Henan Alfa Chemical Co., Ltd 58
GIHI CHEMICALS CO.,LIMITED 58
Aladdin Scientific 58
Amadis Chemical Company Limited 58
Shanghai Hao Biological Technology Co., Ltd. 58

314-50-1(OROTIDINE)Related Search:

OROTIDINE-5'-MONOPHOSPHATE*PYROPHOSPHORYLASE FROM BR Orotidine-5'-Phosphate Decarboxylase OROTIDINE-5'-MONOPHOSPHATE*DECARBOXYLASE PURIFIED FR orotidine 5'-monophosphate OROTIDINE-5'-PHOSPHATE*PYROPHOSPHORYLASE AND OROTID
OROTIC ACID MONOHYDRATE OROTIDINE 2-(2-METHYL-THIAZOL-4-YL)-PHENOL 6-FORMYL-URACIL MONOHYDRATE 6-(HYDROXYMETHYL)URACIL
N-N-bis(2-hydroxyethyl)formamide orotidine 5'-monophosphate trisodium salt,OROTIDINE 5'-MONOPHOSPHATE SODIUM SALT,orotidine 5'-monophosphate trisodium acrylic acid, compound with 2-aminoethanol (1:1)
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OROTIDINE URIDINE-6-CARBOXYLIC ACID URIDIN-6-CARBOXYLIC ACID Orotidine (Uridine-6-carboxylic acid) 1,2,3,6-Tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-4-pyrimidinecarboxylic acid 6-Carboxyuridine 3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-2,6-diketo-pyrimidine-4-carboxylic acid Orotidine ,98% orotidine free acid approx. 90% 3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,6-dioxopyrimidine-4-carboxylic acid 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl- 4-Pyrimidinecarboxylicacid, 1,2,3,6-tetrahydro-2,6-dioxo-3-b-D-ribofuranosyl- 3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid 314-50-1 C10H13N2O11P C10H12N2O8 Biochemicals and Reagents BioChemical Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs