2,4-DIHYDROXY-6-METHYLBENZOIC ACID
- CAS No.
- 480-64-8
- Chemical Name:
- 2,4-DIHYDROXY-6-METHYLBENZOIC ACID
- Synonyms
- 133346;Orsellic acid;o-orsellinicaci;ORSELLINIC ACID;o-orsellinic acid;ORSELLINIC ACID MONOHYDRATE;2,4-DIHYDROXY-6-METHYLBENZOIC ACID;6-Methyl-2,4-dihydroxybenzoic acid;2-Methyl-4,6-dihydroxybenzoic acid;Benzoic acid, 2,4-dihydroxy-6-Methyl-
- CBNumber:
- CB1185500
- Molecular Formula:
- C8H8O4
- Molecular Weight:
- 168.15
- MOL File:
- 480-64-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/3/29 18:52:01
| Melting point | 173-174°C |
|---|---|
| Boiling point | 257.07°C (rough estimate) |
| Density | 1.3037 (rough estimate) |
| refractive index | 1.5090 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | pK (25°) 3.90 |
| color | White to Pale Gray |
| Water Solubility | Soluble in water, dimethyl sulfoxide or 100% ethanol. |
| Stability | Hygroscopic |
| CAS DataBase Reference | 480-64-8 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| NFPA 704 |
|
2,4-DIHYDROXY-6-METHYLBENZOIC ACID price More Price(2)
2,4-DIHYDROXY-6-METHYLBENZOIC ACID Chemical Properties,Uses,Production
Description
Orsellinic acid is a fungal metabolite and benzoic acid derivative with antioxidant and neuroprotective activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals with an IC50 value of 5 mM. Orsellinic acid (1 μg/ml) prevents PARP cleavage induced by platelet-activating factor (PAF) in PC12-AC cells and PAF-induced cytotoxicity in PAF receptor null (Pafr-/-) mouse cerebellar granule cells.
Uses
Orsellinic acid is a benzoic acid compound shown to block PAF-mediated neuronal apoptosis.
Definition
ChEBI: A dihydroxybenzoic acid that is 2,4-dihydroxybenzoic acid in which the hydrogen at position 6 is replaced by a methyl group.
Biosynthesis
One of the simplest polyketide derivatives, orsellinic acid is widely distributed in fungi. It is biosynthesised from an acetate starter unit and three malonyl units, as shown in Figure. Intramolecular condensation of the polyketide chain gives orsellinic acid without further modification.
The biosynthesis of orsellinic acid.
2,4-DIHYDROXY-6-METHYLBENZOIC ACID Preparation Products And Raw materials
Raw materials
1of3
chevron_rightPreparation Products
2,4-DIHYDROXY-6-METHYLBENZOIC ACID Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GRK RESEARCH LABORATORIES PVT LTD | +91-8249607014 +91-9849401944 | Hyderabad, India | 205 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20361 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
| Henan Alfa Chemical Co., Ltd | +8618339805032 | China | 13096 | 58 | Inquiry |
480-64-8(2,4-DIHYDROXY-6-METHYLBENZOIC ACID)Related Search:
1of4
chevron_right