EVERNIC ACID

EVERNIC ACID Structure
CAS No.
537-09-7
Chemical Name:
EVERNIC ACID
Synonyms
Nsc81164;EVERNIC ACID;LECANORIC ACID METHYL ETHER;EVERNIC ACID YELLOW CRYSTALS;orsellinic acid 4-everninate;Wln: qr cq E1 dvovr bq F1 do1;4-[(4-methoxy-6-methylsalicyloyl)oxy]-6-methylsalicylic acid;6-cresoticacid,4-methoxy-4-esterwith6-methyl-beta-resorcylate;6-cresoticacid,4-methoxy-4-esterwith6-methyl-beta-resorcylicacid;2,6-Cresotic acid, 4-methoxy-, 4-ester with 6-methyl-.beta.-resorcylate
CBNumber:
CB4395269
Molecular Formula:
C17H16O7
Molecular Weight:
332.3
MOL File:
537-09-7.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:09

EVERNIC ACID Properties

Melting point 166-167°C
solubility DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 0.5 mg/ml
form A crystalline solid
color White to off-white
LogP 5.030 (est)

EVERNIC ACID Chemical Properties,Uses,Production

Description

Evernic acid is a secondary metabolite produced by some species of lichen that can bind to allosteric sites on the protein surface of FAS-II enzymes and produce antibacterial and antiplasmodial effects. It inhibits two key plasmodial FAS-II enzymes PfFabZ and PfFabI (IC50 = 10.7 and 36.1 μM, respectively) but shows low efficacy against the malaria parasite P. berghei (IC50 = 77.3 μM).

EVERNIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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LECANORIC ACID METHYL ETHER EVERNIC ACID 2-HYDROXY-4-[2-HYDROXY-4-METHOXY-6-METHYLBENZOYLOXY]-6-METHYLBENZOIC ACID 6-cresoticacid,4-methoxy-4-esterwith6-methyl-beta-resorcylate 6-cresoticacid,4-methoxy-4-esterwith6-methyl-beta-resorcylicacid benzoicacid,2-hydroxy-4-((2-hydroxy-4-methoxy-6-methylbenzoyl)oxy)-6-methyl 4-[(4-methoxy-6-methylsalicyloyl)oxy]-6-methylsalicylic acid EVERNIC ACID YELLOW CRYSTALS 2,6-Cresotic acid, 4-methoxy-, 4-ester with 6-methyl-.beta.-resorcylate Nsc81164 Wln: qr cq E1 dvovr bq F1 do1 orsellinic acid 4-everninate 537-09-7 Plant Oils, Toxins, Phenolic Acids & Derivatives