2-ヒドロキシ-4-[(2-ヒドロキシ-4-メトキシ-6-メチルベンゾイル)オキシ]-6-メチル安息香酸 化学特性,用途語,生産方法
説明
Evernic acid is a secondary metabolite produced by some species of lichen that can bind to allosteric sites on the protein surface of FAS-II enzymes and produce antibacterial and antiplasmodial effects. It inhibits two key plasmodial FAS-II enzymes
PfFabZ and
PfFabI (IC
50 = 10.7 and 36.1 μM, respectively) but shows low efficacy against the malaria parasite
P. berghei (IC
50 = 77.3 μM).
2-ヒドロキシ-4-[(2-ヒドロキシ-4-メトキシ-6-メチルベンゾイル)オキシ]-6-メチル安息香酸 上流と下流の製品情報
原材料
準備製品