DIFFRACTIC ACID

DIFFRACTIC ACID Structure
CAS No.
436-32-8
Chemical Name:
DIFFRACTIC ACID
Synonyms
NSC 5901;NSC 685595;DIFFRACTIC ACID;DIRHIZONIC ACID;diffractaicacid;Difractaic acid;diffracfaic acid;DIFFRACTAIC ACID(SH);DIFFRACTIC ACID USP/EP/BP;beta-resorcylicacid,3,6-dimethyl-,4-(2,4-dimethoxy-3,6-dimethylbenzoate)
CBNumber:
CB7381496
Molecular Formula:
C20H22O7
Molecular Weight:
374.38
MOL File:
436-32-8.mol
MSDS File:
SDS
Modify Date:
2024/7/26 15:15:06

DIFFRACTIC ACID Properties

Melting point 189~190℃
Boiling point 604.9±55.0 °C(Predicted)
Density 1.260±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form A solid
pka 2.66±0.25(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
NFPA 704
0
2 0

DIFFRACTIC ACID Chemical Properties,Uses,Production

Description

Diffractaic acid is a lichen metabolite that has been found in P. magellanica and has diverse biological activities. It is cytotoxic to HCT116, HeLa, and MCF-7 cancer cells (IC50s = 42.2, 64.6, and 93.4 μM, respectively). Diffractaic acid inhibits growth of M. tuberculosis (MIC = 41.7 μM). In vivo, diffractaic acid (25-200 mg/kg) reduces neutrophil infiltration, lipid peroxidation, myeloperoxidase (MPx) activity, and the number of gastric lesions as well as reverses decreases in superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities induced by indomethacin in rat gastric mucosa. Diffractaic acid also has analgesic activity, reducing acetic acid-induced writhing and increasing the pressure pain threshold in mice.

DIFFRACTIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 70)Suppliers
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Shaanxi Pioneer Biotech Co., Ltd . +8613259417953 China 3000 58 Inquiry
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Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 23499 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 China 6210 58 Inquiry
Chengdu Push Bio-Technology Co., Ltd. 028-85370565-229 18080489829 China 8964 60 Inquiry
Wuhan Huangzhen Biochemical Co., Ltd 13795480948 13795480948 China 4958 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9268 58 Inquiry
Xiamen Huijia Biological Technology Co., Ltd. 0592-6020891 CHINA 6979 58 Inquiry
Shanghai Junrui Biotechnology Co., Ltd. 15921420262 CHINA 6010 58 Inquiry

DIFFRACTIC ACID Spectrum

DIRHIZONIC ACID DIFFRACTIC ACID benzoicacid,2,4-dimethoxy-3,6-dimethyl-,4-carboxy-3-hydroxy-2,5-dimethylph beta-resorcylicacid,3,6-dimethyl-,4-(2,4-dimethoxy-3,6-dimethylbenzoate) diffractaicacid 2-Hydroxy-4-(2,4-dimethoxy-3,6-dimethylbenzoyloxy)-3,6-dimethylbenzoic acid 4-(2,4-dimethoxy-3,6-dimethyl-benzoyl)oxy-2-hydroxy-3,6-dimethyl-benzoic acid 4-(2,4-dimethoxy-3,6-dimethylbenzoyl)oxy-2-hydroxy-3,6-dimethylbenzoic acid 4-(2,4-dimethoxy-3,6-dimethyl-phenyl)carbonyloxy-2-hydroxy-3,6-dimethyl-benzoic acid DIFFRACTAIC ACID(SH) diffracfaic acid NSC 685595 NSC 5901 Difractaic acid Benzoic acid,2,4-dimethoxy-3,6-dimethyl-, 4-carboxy-3-hydroxy-2,5-dimethylphenyl ester DIFFRACTIC ACID USP/EP/BP 436-32-8