SCHRADAN
- CAS No.
- 152-16-9
- Chemical Name:
- SCHRADAN
- Synonyms
- OMPA;ompax;sytam;pestox;systam;ompatox;pestox3;SCHRADEN;SCHADRAN;SCHRADAN
- CBNumber:
- CB1238792
- Molecular Formula:
- C8H24N4O3P2
- Molecular Weight:
- 286.25
- MOL File:
- 152-16-9.mol
- Modify Date:
- 2024/3/14 15:18:25
| Melting point | 17℃ |
|---|---|
| Boiling point | bp0.5 120-125°; bp2.0 154° |
| Density | 1.24 g/cm3 (25 ºC) |
| refractive index | 1.4698 (589.3 nm 20℃) |
| form | liquid |
| pka | 0.85±0.70(Predicted) |
| color | Viscous liquid |
| CAS DataBase Reference | 152-16-9 |
| EPA Substance Registry System | Schradan (152-16-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H300-H310 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501-P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501 |
| Hazard Codes | T+ |
| Risk Statements | 27/28 |
| Safety Statements | 36/37-38-45 |
| RIDADR | 3018 |
| HazardClass | 6.1(a) |
| PackingGroup | I |
| HS Code | 29299090 |
| Toxicity | LD50 in male, female rats (mg/kg): 9.1, 42 orally; 15, 44 dermally (Gaines) |
SCHRADAN Chemical Properties,Uses,Production
Chemical Properties
OMPA is a colorless liquid in crude form; otherwise, it is a dark brown viscous liquid.
Uses
Insecticide.
General Description
Schradan, octamethyl pyrophosphoramide(OMPA), bis[bisdimethylaminophosphonous] anhydride(Pestox III), is a viscous liquid that is miscible with waterand soluble in most organic solvents. It is not hydrolyzed byalkalies or water but is hydrolyzed by acids. Schradan isused as a systemic insecticide for plants, being absorbed bythe plants without appreciable injury. Insects feeding on theplant are incapacitated.
Schradan is a weak inhibitor of cholinesterases in vitro.In vivo, it is metabolized to the very strong inhibitor hydroxymethylOMPA. Hydroxymethyl OMPA is not stable andis metabolized further to the N-methoxide, which is a weakinhibitor of cholinesterase.
Reactivity Profile
Organophosphates, such as SCHRADAN, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Health Hazard
Extremely toxic; probable oral lethal dose in humans is 5-50 mg/kg, between 7 drops and 1 teaspoonful for a 150 lb. person. It is highly toxic when inhaled. Material is a cholinesterase inhibitor. It is similar in action to other organophosphorous pesticides in its toxicity. It is slightly less toxic than parathion. Gastrointestinal, neurologic and respiratory symptoms may accompany poisoning with SCHRADAN. High doses may cause a toxic psychosis similar to acute alcoholism. Persons taking phenobarbital and phenaglycodol together, glutethimide, chlorpromazine hydrochloride, or meprobamate may be at greater risk. These drugs appear to enhance the toxicity of the material markedly.
Fire Hazard
When heated to decomposition, SCHRADAN can emit highly toxic fumes of oxides of phosphorus. Decomposes when mixed with acid. Hydrolyzed under acid conditions to dimethylamine and orthophosphoric acid.
Safety Profile
Poison by ingestion, inhalation,skin contact, intraperitoneal, intravenous, subcutaneous,and ocular routes. Human systemic effects by ingestion: acholinesterase inhibitor. Has been found to inhibitperipheral cholinesterase without pronounced effects o
Potential Exposure
Material is used as a systemic insecticide for plants and as an acaricide. Not registered as a pesticide in the United States.
Shipping
UN3018 Organophosphorus pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
Incompatibilities
Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides and active metals. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. Acids.
Waste Disposal
In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.