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ABT-492

ABT-492 Structure
CAS No.
189279-58-1
Chemical Name:
ABT-492
Synonyms
Delafloxacin;Delafloxacine;Delafloxacin Impurity;WQ3034;CS-711;ABT-492;RX-3341;CS-2335;Delafloxacinum;ABT492/ABT-492
CBNumber:
CB12561456
Molecular Formula:
C18H12ClF3N4O4
Molecular Weight:
440.76
MOL File:
189279-58-1.mol
Modify Date:
2024/5/13 18:00:15
Request For Quotation

ABT-492 Properties

Melting point 238-241℃
Boiling point 698.5±55.0 °C(Predicted)
Density 1.796
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Very Slightly, Heated, Sonicated)
pka 5.49±0.50(Predicted)
form powder
color white to beige
CAS DataBase Reference 189279-58-1

ABT-492 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML1869 Delafloxacin ≥98% (HPLC) 189279-58-1 5MG ₹10619.33 2022-06-14 Buy
Sigma-Aldrich(India) SML1869 Delafloxacin ≥98% (HPLC) 189279-58-1 25MG ₹42877.83 2022-06-14 Buy
Product number Packaging Price Buy
SML1869 5MG ₹10619.33 Buy
SML1869 25MG ₹42877.83 Buy

ABT-492 Chemical Properties,Uses,Production

Uses

Delafloxacin is a potent agent and broad-spectrum anionic fluoroquinolone against Streptococcus pneumoniae and diverse group of pathogens.

Biochem/physiol Actions

Delafloxacin is a fluoroquinolone antibiotic active against both Gram-negative and Gram-positive bacteria such as MRSA. Delafloxacin targets both DNA gyrase and topoisomerase IV, inhibiting DNA synthesis. Unlike most fluoroquinolones, delafloxacin is weakly acidic, which increases its potency in an acidic environments such as those existing in inflammatory cells and in skin and soft tissue infections. Delafloxacin shows good activity against most fluoroquinolone-resistant strains.

ABT-492 Preparation Products And Raw materials

Raw materials

Benzenepropanoic acid, α-(ethoxymethylene)-2,4,5-trifluoro-β-oxo-, ethyl ester 3-Quinolinecarboxylic acid, 1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6,7-difluoro-1,4-dihydro-4-oxo-, ethyl ester 1-(6-Amino-3,5-difluoro-2-pyridinyl)-8-chloro-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid 3-Quinolinecarboxylic acid, 1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-1,4-dihydro-7-[3-(2-methyl-1-oxopropoxy)-1-azetidinyl]-4-oxo-, ethyl ester Ethyl 2,4,5-trifluorobenzoylacetate
2,4,5-Trifluorobenzoic acid 3-quinolinecarboxylic acid, 1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6,7-difluoro-1,4-dihydro-4-oxo-, ethyl ester 2,4,5-Trifluorobenzoyl chloride ETHYL 3-(3-CHLORO-2,4,5-TRIFLUOROPHENYL)-3-OXOPROPANOATE 3-Hydroxyazetidine hydrochloride
1-Methylpyrrolidine
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Preparation Products

ABT-492 MegluMine

ABT-492 Suppliers

Global( 162)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
hebei hongtan Biotechnology Co., Ltd +86-86-1913198-3935 +8617331935328 China 973 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21669 55 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
ENBRIDGE PHARMTECH CO., LTD. +8613812269233 China 303 58 Inquiry
Supplier Advantage
Pharma Affiliates 58
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
SynZeal Research Pvt Ltd 58
hebei hongtan Biotechnology Co., Ltd 58
Henan Tianfu Chemical Co.,Ltd. 55
ATK CHEMICAL COMPANY LIMITED 60
CONIER CHEM AND PHARMA LIMITED 58
career henan chemical co 58
ENBRIDGE PHARMTECH CO., LTD. 58

ABT-492 Spectrum

ABT-492(189279-58-1)1HNMR

189279-58-1(ABT-492)Related Search:

2,6-DIAMINOPIMELIC ACID 2,4-Dihydroxypyridine
ABT-492 1-(6-Amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy-1-azetidinyl)-4-oxo-3-quinolinecarboxylic acid Delafloxacinum 3-Quinolinecarboxylic acid, 1-(6-aMino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy-1-azetidinyl)-4-oxo- WQ3034 ABT-492(WQ-3034) ABT492/ABT-492 1-(6-aMino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid RX-3341 ABT-492/Delafloxacin Delafloxacin, ABT-492 3-(6-Amino-3,5-difluoro-pyridin-2-ylamino)-2-{2,5-difluoro-4-[3-(3-methyl-2-oxo-butyl)-cyclobutyl]-benzoyl}-acrylic acid ethyl ester DELAFLOXACIN;RX-3341;WQ-3034;ABT492 1-(6-Amino-3,5-difluoro-pyridin-2-yl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy-1-azetidinyl)-4-oxo-quinolin-3-carboxylic acid Delafloxacin Free Acid DELAFLOXACIN;DELAFLOXACINUM;RX-3341;WQ-3034;ABT492;ABT 492 CS-2335 DELAFLOXACINUM; RX-3341; WQ-3034; ABT492; ABT 492; ABT-492;WQ3034;WQ 3034 CS-711 1-(6-Amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-... Delafloxacin impurities7 Delafloxacin Delafloxacin Impurity Delafloxacine 2H5]-Delafloxacin Delafloxacin API 189279-58-1 C18H12ClF3N4O4 API