Adelmidrol
- CAS No.
- 1675-66-7
- Chemical Name:
- Adelmidrol
- Synonyms
- Demiqu;NSC 27132;Adelmidrol;AdelMitrol;AdelMitrol USP/EP/BP;N,N'-Bis(2-hydroxyethyl)nonanediamide;N1,N9-bis(2-hydroxyethyl)-nonanediamide;Nonanediamide, N1,N9-bis(2-hydroxyethyl)-;China biggest manufacturer,AdelMitrol,1675-66-7;NF-κB,Nuclear factor-kappaB,PPAR,COX,Adelmidrol,Cyclooxygenase,Peroxisome proliferator-activated receptors,inhibit,Inhibitor,Nuclear factor-κB
- CBNumber:
- CB12657232
- Molecular Formula:
- C13H26N2O4
- Molecular Weight:
- 274.36
- MOL File:
- 1675-66-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/11/20 11:41:24
| Melting point | 132-134℃ |
|---|---|
| Boiling point | 596.4±45.0 °C(Predicted) |
| Density | 1.097±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility |
DMSO:77.5(Max Conc. mg/mL);282.47(Max Conc. mM) Ethanol:28.0(Max Conc. mg/mL);102.06(Max Conc. mM) Water:55.0(Max Conc. mg/mL);200.47(Max Conc. mM) |
| pka | 14.19±0.10(Predicted) |
| form | Solid |
| color | White to off-white |
| InChI | InChI=1S/C13H26N2O4/c16-10-8-14-12(18)6-4-2-1-3-5-7-13(19)15-9-11-17/h16-17H,1-11H2,(H,14,18)(H,15,19) |
| InChIKey | PAHZPHDAJQIETD-UHFFFAOYSA-N |
| SMILES | C(NCCO)(=O)CCCCCCCC(NCCO)=O |
Adelmidrol Chemical Properties,Uses,Production
Description
N,N'-Bis(2-hydroxyethyl)nonanediamide, also named Admidol, is an anti-inflammatory ethanolamide derivative. It is hydrophilic and hydrophobic, favoring its solubility in water and organic media. As an naturally occurring saturated dicarboxylic acid, it is found in trace amounts in the human body and in some whole grains. Adelmidrol is an analogue of palmitoylethanolamide (PEA), which is a well-known anti-inflammatory and anti-oxidant compound. Adelmidrol was able to manage the significant incapacity of antioxidants and elevation of the oxidant burden[1-2].
References
[1] Cordaro M, et al. Adelmidrol, a Palmitoylethanolamide Analogue, as a New Pharmacological Treatment for the Management of Inflammatory Bowel Disease. BIOCHEMICAL PHARMACOLOGY, 2016; 90: 549-561
[2] Fusco R, et al. Adelmidrol: A New Promising Antioxidant and Anti-Inflammatory Therapeutic Tool in Pulmonary Fibrosis. Antioxidants, 2020; 9.
[3] Guida F, et al. Targeting Neuroinflammation in Osteoarthritis with Intra-Articular Adelmidrol. 2022; 12.
Adelmidrol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | China | 49977 | 58 | Inquiry |
| LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43340 | 58 | Inquiry |
| Hangzhou FandaChem Co.,Ltd. | +8615858145714 | China | 8771 | 55 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32965 | 60 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49374 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29810 | 58 | Inquiry |
| Univar Solutions(China) Co., Ltd. | +8615902132654 | China | 654 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32161 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | China | 34563 | 58 | Inquiry |