FTI-277

FTI-277 Structure
CAS No.
170006-73-2
Chemical Name:
FTI-277
Synonyms
FTI-277;FTI-277;FTI277;METHYL[N-[2-PHENYL-4-N-[2(R)-AMINO-3-MERCAPTOPROPYLAMINO] BENZOYL]]-METHIONATE, TFA;N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-L-methionine methyl ester;N-[4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE METHYL ESTER TRIFLUOROACETATE SALT;L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-, methyl ester;N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt
CBNumber:
CB1266050
Molecular Formula:
C22H29N3O3S2
Molecular Weight:
447.61
MOL File:
170006-73-2.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:12

FTI-277 Properties

Boiling point 684.2±55.0 °C(Predicted)
Density 1.222±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility H2O: soluble
pka 9.81±0.10(Predicted)
form amorphous semi-solid

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3

FTI-277 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) F9803 FTI-277 trifluoroacetate salt ≥95% (HPLC), film 170006-73-2 1MG ₹17980.33 2022-06-14 Buy
Sigma-Aldrich(India) F9803 FTI-277 trifluoroacetate salt ≥95% (HPLC), film 170006-73-2 5MG ₹62113.85 2022-06-14 Buy
Product number Packaging Price Buy
F9803 1MG ₹17980.33 Buy
F9803 5MG ₹62113.85 Buy

FTI-277 Chemical Properties,Uses,Production

Uses

Farnesyltransferase inhibitor 277 (FTI-277) has been used to:

  • inhibit protein farnesylation in breast cell lines.
  • in marrow-isolated adult multilineage inducible cells (MIAMI).
  • inhibition of farnesyl transferase in CV-1 in Origin with SV40 genes cells (COS-7).

Biochem/physiol Actions

Farnesyltransferase inhibitor 277 (FTI-277) mediates apoptosis in multiple myeloma and is regarded as a potential therapeutic agent.

FTI-277 Preparation Products And Raw materials

Raw materials

Preparation Products

FTI-277 Suppliers

Global( 59)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29825 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3136 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Beijing Bai Ao Si Biotechnology Co., Ltd. 010-60291560 CHINA 6999 58 Inquiry
Shanghai Yuda Industrial Co., Ltd. 021-64133189 13788995069 CHINA 6107 58 Inquiry
Shanghai Hao Biological Technology Co., Ltd. 021-80370006 13585899102 CHINA 6805 58 Inquiry
Xiamen Huijia Biological Technology Co., Ltd. 0592-6020891 CHINA 6979 58 Inquiry
METHYL[N-[2-PHENYL-4-N-[2(R)-AMINO-3-MERCAPTOPROPYLAMINO] BENZOYL]]-METHIONATE, TFA FTI-277 N-[4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE METHYL ESTER TRIFLUOROACETATE SALT N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-L-methionine methyl ester FTI-277;FTI277 L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-, methyl ester 170006-73-2 C22H29N3O3S2 C22H29N3O3S2C2HF3O2