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FTI-277

FTI-277 Structure
  • ₹17980.33 - ₹62113.85
  • Product name: FTI-277
  • CAS: 170006-73-2
  • MF: C22H29N3O3S2
  • MW: 447.61
  • EINECS:
  • MDL Number:MFCD00952925
  • Synonyms:METHYL[N-[2-PHENYL-4-N-[2(R)-AMINO-3-MERCAPTOPROPYLAMINO] BENZOYL]]-METHIONATE, TFA;FTI-277;N-[4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE METHYL ESTER TRIFLUOROACETATE SALT;N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt;N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-L-methionine methyl ester;FTI-277;FTI277;L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-, methyl ester
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberF9803
  • Product descriptionFTI-277 trifluoroacetate salt ≥95% (HPLC), film
  • Packaging1MG
  • Price₹17980.33
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberF9803
  • Product descriptionFTI-277 trifluoroacetate salt ≥95% (HPLC), film
  • Packaging5MG
  • Price₹62113.85
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) F9803 FTI-277 trifluoroacetate salt ≥95% (HPLC), film 1MG ₹17980.33 2022-06-14 Buy
Sigma-Aldrich(India) F9803 FTI-277 trifluoroacetate salt ≥95% (HPLC), film 5MG ₹62113.85 2022-06-14 Buy

Properties

Boiling point :684.2±55.0 °C(Predicted)
Density :1.222±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :H2O: soluble
pka :9.81±0.10(Predicted)
form :amorphous semi-solid

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

FTI-277 trifluoroacetate salt is an inhibitor of farnesyl transferase (FTase). Studies show the compound to be a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling.