Chinese english Japanese Germany Korea
ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Standard Substance >tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate

tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate

tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate Structure
CAS No.
1210348-34-7
Chemical Name:
tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate
Synonyms
Tert-Butyl(1R,2S,5S)-2-azido-5-[(diMethylaMino)carbonyl]cyclohexylcarbaMate oxalic acid;N-[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]-Carbamic acid, 1,1-dimethylethyl ester, ethanedioate (1:1);Edoxaban-1;EBD3313800;Yidu Saban Impurity A;Edoxaban Intermediate II;Idosaiban intermediate 2;2EthanediaMide iMpurity A;EthanediaMide iMpurity A;(1S,2R,4S)-2-[(tert-Butoxyc
CBNumber:
CB12670860
Molecular Formula:
C16H29N3O7
Molecular Weight:
375.42
MOL File:
1210348-34-7.mol
MSDS File:
SDS
Modify Date:
2023/12/21 13:59:16
Request For Quotation

tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate Properties

storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White
InChI InChI=1/C14H27N3O3.C2H2O4/c1-14(2,3)20-13(19)16-11-8-9(6-7-10(11)15)12(18)17(4)5;3-1(4)2(5)6/h9-11H,6-8,15H2,1-5H3,(H,16,19);(H,3,4)(H,5,6)/t9-,10-,11+;/s3
InChIKey IERZZGXDUZIMSC-FPTARDKGNA-N
SMILES C(=O)(O)C(=O)O.N([C@H]1[C@H](CC[C@H](C(=O)N(C)C)C1)N)C(=O)OC(C)(C)C |&1:7,8,11,r|
CAS DataBase Reference 1210348-34-7

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate Chemical Properties,Uses,Production

Uses

tert-Butyl [(1R,2S,5S)-2-Amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate Oxalate is a starting material and useful building block of various pharmaceuticals.

Uses

Tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate is also called EthanediaMide iMpurity A. It is a starting material and useful component of various pharmaceuticals. As an organic synthesis intermediate and pharmaceutical intermediate. It could be used in the synthesis and research of the EthanediaMide.

Synthesis

Tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate is prepared by the reaction of benzyl N-[(1S,2R,4S)-2-{[(tert-butoxy)carbonyl]amino}-4-(dimethylcarbamoyl)cyclohexyl]carbamate and Oxalic Acid. The steps are as follows:
Pd-C (230 mg) was added to a solution (35 mL) of benzyl t-butyl{(1S,2R,4S)-4-[(dimethylamino)carbonyl]cyclohexan-1,2-diyl}biscarbamate (2.3 g) in ethanol, and the mixture was stirred in a hydrogen atmosphere for 16 hours. Pd-C was removed by filtration, and the filtrate was concentrated under reduced pressure. Ethyl acetate (20 mL) and anhydrous oxalic acid (493.6 mg) were added to the residue, followed by stirring at room temperature for 17 hours. The formed crystals were recovered by filtration, to thereby yield 1.93 g of the Tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate.
tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate synthesis

tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate Preparation Products And Raw materials

Raw materials

Preparation Products

tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate Suppliers

Global( 261)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
EPOCH LABS +91-7702174901 +91-9515109812 Hyderabad, India 68 58 Inquiry
INTEGRAL BIO SCIENCES +91-1204663222 +91-9177003936 New Delhi, India 9 58 Inquiry
GMFC LABS PVT LTD +91-9133370278 +91-9133370278 Hyderabad, India 44 58 Inquiry
CVR Life sciences Pvt Ltd +91-7386789224 +91-9912960099 Hyderabad, India 22 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Eaglech（shanghai）Pharmaceutical Co., Ltd +8613884467586 China 8 58 Inquiry
Zhuhai Hairuide Bioscience and Technology Co., Ltd +8618928027945 China 97 58 Inquiry
Shanghai Qianyi New Material Co., Ltd. +8618083322317 China 878 58 Inquiry
Shanghai Joiny Pharmaceutical Co.,LTD +8613681955282 China 255 58 Inquiry
Hangzhou ICH Biofarm Co., Ltd +86-0571-28186870; +undefined8613073685410 China 998 58 Inquiry
Supplier Advantage
EPOCH LABS 58
INTEGRAL BIO SCIENCES 58
GMFC LABS PVT LTD 58
CVR Life sciences Pvt Ltd 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Eaglech（shanghai）Pharmaceutical Co., Ltd 58
Zhuhai Hairuide Bioscience and Technology Co., Ltd 58
Shanghai Qianyi New Material Co., Ltd. 58
Shanghai Joiny Pharmaceutical Co.,LTD 58
Hangzhou ICH Biofarm Co., Ltd 58

tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate Spectrum

EthanediaMide iMpurity A(1210348-34-7)1HNMR

1210348-34-7(tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate)Related Search:

2-BroMo-5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine (1R,3R,4R)-3-AMino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester 2-Amino-5-chloropyridine EthanediaMide, N1-(5-chlo... EthanediaMide, N1-(5-chlo...
(1R,2R,4S)-2-[(tert-butoxycarbonyl)aMino]-4-[(diMethylaMino)carbonyl]cyclohexyl Methanesulfonate Thiazolo[5,4-c]pyridine, 4,5,6,7-tetrahydro-5-methyl- 2-(((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetic acid EthanediaMide iMpurity F EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]-
5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride Tert-Butyl(1R,2S,5S)-2-azido-5-[(dimethylamino)carbonyl]cyclohexylcarbamate oxalic acid Ethyl 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate hydrochloride tert-butyl (1R,2S,5S)-2-aMino-5-(diMethylcarbaMoyl)cyclohexylcarbaMate Argatroban
Flurbiprofen VILAZODONE (1R,3S,4R)-3-Amino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester hydrochloride
chevron_left

1of4

chevron_right
oxalic acid tert-butyl N-[(1R,2S,5S)-2-aMino-5-(diMethylcarbaMoyl)cyclohexyl]carbaMate (2-Azido-5-diMethylcarbaMoyl-cyclohexyl)-carbaMic acid tert-butyl esteroxalic acid 2EthanediaMide iMpurity A tert-Butyl [(1R,2S,5S)-2-aMino-5-[(diMethylaMino)carbonyl]cyclohexyl]carbaMate oxalate tert-Butyl [(1R,2S,5S)-2-aMino-5-[(diMethylaMino)carbonyl]cyclohexyl]carbaMate oxalate(for Edoxaban) tert-butyl N-[(1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl]carbamate (1S,2R,4S)-2-[(tert-Butoxycarbonyl)Amino ]-4-[( dimethylamino)carbonyl]- cyclohexyl ammonia oxalate tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate oxalate Edoxaban Intermediate II tert-butyl N-[(1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl]carbamate oxalate Edoxaban Impurity 15 Oxalate Tert-Butyl(1R,2S,5S)-2-azido-5-[(diMethylaMino)carbonyl]cyclohexylcarbaMate oxalate EthanediaMide iMpurity A/Edoxaban Intermediate II tert-butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate oxalic acid Edoxaban-1 (1S,2R,4S)-2-[(tert-Butoxyc tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate(For export only) Tert-butyl(1R, 2S, 5S)-2-amino-5-((dimethylamino)carbonyl)cyclohexylcarbamate oxalic acid (1S,2R,4S)-2-[(tert-Butoxycarbonyl]- cyclohexyl ammonia oxalate (1s, 2R, 4S) - 1-amino-4 - (dimethylaminocarbonyl) - cyclohexyl-2-carbamate tert butyl oxalic acid Idosaiban intermediate 2 Tert-Butyl(1R,2S,5S)-2-azido-5-[(diMethylaMino)carbonyl]cyclohexylcarbaMate oxalic acid N-[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]-Carbamic acid, 1,1-dimethylethyl ester, ethanedioate (1:1) ert-Butyl[(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamateoxalate EBD3313800 Tertiary Butyl [1R,2S, 5S]-2-Amino-5-Dimethylcarboyl) Cyclohexylcarbamate Oxalate tert-butyl (1R,2S,5S)-5-(dimethylcarbamoyl)-2-aminocyclohexylcarbamate oxalate Yidu Saban Impurity A Edoxaban Impurity A（Oxalate） [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate carbamic acid Tert-Butyl((1R,2S,5S)-2-amino-5-(dimethyl- carbamoyl)cyclohexyl)carbarmate oxalate EthanediaMide iMpurity A Edoxaban Impurity 9 Oxalate 1210348-34-7 365998-36-8 C14H27N3O3C2H2O4