(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID

CAS No.: 16626-02-1

Chemical Name:: (S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID

Synonyms: H-L-Trp(5-F)-OH*H2O;L-5-FLUOROTRYPTOPHAN;5-FLUORO-L-TRYPTOPHAN;H-5-FLUORO-TRP-OH H2O;Tryptophan Impurity 54;5-fluoro-L-tryptophans;L-Tryptophan, 5-fluoro-;5-Fluoro-tryptophan monohydrate;L-5-fluorotryptophan monohydrate;5-FLUORO-L-TRYPTOPHAN MONOHYDRATE

CBNumber:: CB1274150

Molecular Formula:: C11H11FN2O2

Molecular Weight:: 222.22

MOL File:: 16626-02-1.mol

MSDS File:: SDS

Modify Date:: 2022/12/30 16:20:48

Request For Quotation

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Properties

Melting point	238-239 °C
Boiling point	450.7±45.0 °C(Predicted)
Density	1.442±0.06 g/cm3(Predicted)
storage temp.	2-8°C
pka	2.21±0.10(Predicted)
BRN	5052680

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Safety Statements	22-24/25
WGK Germany	3
F	10
HS Code	2933998090

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	47568	5-Fluoro-L-tryptophan ≥98.0% (HPLC)	16626-02-1	25MG	₹8080	2022-06-14	Buy

Product number	Packaging	Price	Buy
47568	25MG	₹8080	Buy

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Chemical Properties,Uses,Production

Uses

Exogenous 5-fluoro-Trp is incorporated into proteins in normal protein synthesis. Since ¹⁹F is a useful reporter group, this provides a method for studying enzyme mechanisms by NMR.

Biochem/physiol Actions

5-Fluoro-Trp is nonspecifically cytotoxic. It is believed this is due to malfunctioning enzymes that have had replacements of Trp residues by 5-fluoro-Trp. However, at least one case is known where 5-fluoro-Trp substitution leads to significantly greater catalytic activity.

Purification Methods

Recrystallise it from EtOH, aqueous EtOH or AcOH. Also purify it by passage through a Dowex AG1x2 (acetate form) column and recrystallise the L-enantiomer (from enzymic enrichment) from H2O/EtOH, m 158-163o(dec), [] D -8.3o (c 2.5, N NaOH). [Coy et al. Biochemistry 13 3550 1974, Beilstein 22/14 V 116.]

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID Suppliers

Global( 78)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	China	7621	58	Inquiry
Nextpeptide Inc	+86-0571-81612335 +8613336028439	China	19915	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58	Inquiry
Amadis Chemical Company Limited	571-89925085	China	131980	58	Inquiry
DONBOO AMINO ACID COMPANY	+8613063595538	China	9365	58	Inquiry
Shanghai Jifeng Biotechnology Co., Ltd.	021-61263377 15023907684	China	8131	58	Inquiry
Zhengzhou convergence chemical co., LTD	0371-0371-55153829 18003835034	China	9459	58	Inquiry
Beijing OKA biological technology co., LTD	010-010-010-62971590 18548936886	China	6897	58	Inquiry
Kanghua (Shanghai) New Drug Development Co., Ltd.	021-61263370 18901917034	China	5637	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
Jinan Carbotang Biotech Co.,Ltd.	58
Nextpeptide Inc	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
DONBOO AMINO ACID COMPANY	58
Shanghai Jifeng Biotechnology Co., Ltd.	58
Zhengzhou convergence chemical co., LTD	58
Beijing OKA biological technology co., LTD	58
Kanghua (Shanghai) New Drug Development Co., Ltd.	58

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5-FLUORO-L-TRYPTOPHAN 5-FLUORO-L-TRYPTOPHAN MONOHYDRATE H-5-FLUORO-TRP-OH H2O L-5-FLUOROTRYPTOPHAN (S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID 5-Fluoro-tryptophan monohydrate H-L-Trp(5-F)-OH*H2O L-5-fluorotryptophan monohydrate (S)-5-Fluoro-α-amino-1H-indole-3-propionic acid (S)-α-Amino-5-fluoro-1H-indole-3-propionic acid (S)-2-AMino-3-(5-fluoro-1H-indol-3-yl)propanoic acid L-Tryptophan, 5-fluoro- (2S)-2-amino-3-(5-fluoro-1H-indol-3-yl)propanoic acid 5-Fluoro-L-tryptophan >=98.0% (HPLC) Tryptophan Impurity 54 5-fluoro-L-tryptophans 16626-02-1 C11H11FN2O2H2O BioChemical Biochemicals and Reagents Enzyme Inhibitors Enzyme Inhibitors by Type Enzymes, Inhibitors, and Substrates Substrate Analogs Unnatural Amino Acid Derivatives Tryptophan Derivatives F Enzyme Inhibitors by Type Alphabetic Substrate AnalogsPeptide Synthesis FA - FLEnzyme Inhibitors Indoles and derivatives