11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2

11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2 Structure
CAS No.
53658-98-3
Chemical Name:
11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2
Synonyms
AY 24609;11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2;9-OXO-15R-HYDROXY-16,16-DIMETHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID;Prosta-5,13-dien-1-oic acid, 15-hydroxy-16,16-dimethyl-9-oxo-, (5Z,13E,15R)-
CBNumber:
CB1274529
Molecular Formula:
C22H36O4
Molecular Weight:
364.52
MOL File:
53658-98-3.mol
Modify Date:
2023/6/8 9:03:09

11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2 Properties

solubility DMF: >100 mg/ml (from PGE2); DMSO: >100 mg/ml (from PGE2); Ethanol: >100 mg/ml (from PGE2); PBS pH 7.2: >5 mg/ml (from PGE2)

11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2 Chemical Properties,Uses,Production

Description

11-deoxy-16,16-dimethyl PGE2 is a stable synthetic analog of PGE2. It is an agonist for both EP2 and EP3 receptors. It is an effective inhibitor of gastric acid secretion and ulcer formation in the rat, with ED50 values of 1 mg/kg and 0.021 mg/kg respectively. It is 900 times more potent than PGF in the contraction of human respiratory tract smooth muscle in vitro.

11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2 Preparation Products And Raw materials

Raw materials

Preparation Products

9-OXO-15R-HYDROXY-16,16-DIMETHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID 11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2 AY 24609 Prosta-5,13-dien-1-oic acid, 15-hydroxy-16,16-dimethyl-9-oxo-, (5Z,13E,15R)- 53658-98-3