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tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Structure
CAS No.
1201187-44-1
Chemical Name:
tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate
Synonyms
tert-butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate;Upadacitinib Impurity 3;Upadacitinib Intermediate4;Upadacitinib intermediate2;Intermediate of Upadacitinib (ABT-494);2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine;tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate;N-[5-[(4-Methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-y...;tert-butyl (5-(p-toluenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl)carbamate;2-Methyl-2-propanyl {5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl}carbamate
CBNumber:
CB13102742
Molecular Formula:
C18H20N4O4S
Molecular Weight:
388.44
MOL File:
1201187-44-1.mol
Modify Date:
2023/8/25 16:38:04
Request For Quotation

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Properties

Density 1.35±0.1 g/cm3(Predicted)
pka 9.45±0.43(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Chemical Properties,Uses,Production

Uses

tert-Butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate is a reagent in the synthetic preparation of tricyclic heterocycles and their kinase inhibitory activity. Preparation of novel nitrogen-containing tricyclic compounds as kinase inhibitors for treating immunological and oncological conditions.

Uses

Tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate, also known as upadacitinib intermediate 2, could be used in the synthesis and property studies of upadacitinib. This compound Often used as organic synthesis intermediates and pharmaceutical intermediates. It can be used in laboratory research processes and chemical production processes.

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Preparation Products And Raw materials

Raw materials

N-Tosyl-5-bromo-4,7-diazaindole tert-Butyl carbamate

Preparation Products

tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Suppliers

Global( 197)Suppliers
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Neochemsys Laboratories Pvt Ltd +918498007788 Hyderabad, India 93 58 Inquiry
JIVICHEM SYNTHESIS PVT LTD +91-7028392790 +91-7028392790 Maharashtra, India 337 58 Inquiry
Stereokem Pvt Ltd +91-4029706929 +91-9394224843 Telangana, India 350 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Heading （Nanjing）Pharmtechnologies Co., Ltd. +86-25-58467899-832 +86-13382406280 China 46 58 Inquiry
Hangzhou ICH Biofarm Co., Ltd +86-0571-28186870; +undefined8613073685410 China 985 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20361 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21676 55 Inquiry
Hangzhou FandaChem Co.,Ltd. 008657128800458; +8615858145714 China 9338 55 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
Supplier Advantage
Neochemsys Laboratories Pvt Ltd 58
JIVICHEM SYNTHESIS PVT LTD 58
Stereokem Pvt Ltd 58
SynZeal Research Pvt Ltd 58
Heading （Nanjing）Pharmtechnologies Co., Ltd. 58
Hangzhou ICH Biofarm Co., Ltd 58
Henan Fengda Chemical Co., Ltd 58
Henan Tianfu Chemical Co.,Ltd. 55
Hangzhou FandaChem Co.,Ltd. 55
ATK CHEMICAL COMPANY LIMITED 60

1201187-44-1(tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate)Related Search:

tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate tert-Butyl 3-phenyl-L-alaninate hydrochloride tert-Butyl 3-allyl-4-oxopyrrolidine-1-carboxylate (3R,4S)-3-(2-Bromoacetyl)-4-ethyl-1-pyrrolidinecarboxylic acid phenylmethyl ester
(3R,4S)-1-[(benzyloxy)carbonyl]-4-ethylpyrrolidine-3-carboxylic acid 5-[(4-methylphenyl)sulfonyl]-5H-Pyrrolo[2,3-b]pyrazin-2-amine 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate tert-Butyl (4-methylpiperidin-4-yl)carbamate tert-Butyl 3-oxoazetidine-1-carboxylate
tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate Upadacitinib
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tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate Carbamic acid, N-?[5-?[(4-?methylphenyl)?sulfonyl]?-?5H-?pyrrolo[2,?3-?b]?pyrazin-?2-?yl]?-?, 1,?1-?dimethylethyl ester tert-butyl (5-(p-toluenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl)carbamate Intermediate of Upadacitinib (ABT-494) 2-Methyl-2-propanyl {5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-yl}carbamate Upadacitinib intermediate2 2-(Boc-amino)-5-tosyl-5H-pyrrolo[2,3-b]pyrazine N-[5-[(4-Methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazin-2-y... Upadacitinib Impurity 3 Upadacitinib Intermediate4 tert-butyl N-[5-(4-methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamate N-[5-[(4-Methylphenyl)sulfony!]-5H-pyrrolo[2,3-b]pyrazin-2-yl]carbamic, acid 1, 1-dimethylethyl ester 1201187-44-1