ALPHA-BUNGAROTOXIN

ALPHA-BUNGAROTOXIN Structure
CAS No.
11032-79-4
Chemical Name:
ALPHA-BUNGAROTOXIN
Synonyms
α-BuTX;ALPHA-BGT;ALPHA-BUTX;α-Bungotoxin;A-BUNGAROTOXIN;α-Bungarotoxin;ALPHA-BUNGAROTOXIN;TIANFU-CHEM - ALPHA-BUNGAROTOXIN;M.W. 7984.14 C338H529N97O105S11;BUNGARUS MULTICINCTUS TOXIN, ALPHA
CBNumber:
CB1331318
Molecular Formula:
C50H70O14
Molecular Weight:
895.0824
MOL File:
11032-79-4.mol
Modify Date:
2023/6/30 15:45:59

ALPHA-BUNGAROTOXIN Properties

storage temp. −20°C
solubility Soluble in sterile water
form solid
color white
Water Solubility Soluble in water
CAS DataBase Reference 11032-79-4

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H312-H332
Precautionary statements  P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501
WGK Germany  3
RTECS  QQ4495249
Toxicity chicken,LD50,intramuscular,74ug/kg (0.074mg/kg),Toxicon. Vol. 7, Pg. 89, 1969.

ALPHA-BUNGAROTOXIN price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 203980 α-Bungarotoxin, Bungarus multicinctus - CAS 11032-79-4 - Calbiochem Blocks neuromuscular transmission by irreversible binding to motor end-plate acetylcholine receptor (Kd = 1 pM to 1 nM) but does not depress acetylcho 11032-79-4 1MG ₹17660 2022-06-14 Buy
Product number Packaging Price Buy
203980 1MG ₹17660 Buy

ALPHA-BUNGAROTOXIN Chemical Properties,Uses,Production

Chemical Properties

Single polypeptide weight; molecular weight of 8000.

Definition

A protein that binds specifically to acetylcholine receptors.

General Description

Blocks neuromuscular transmission by irreversible binding to motor end-plate acetylcholine receptor (Kd = 1 pM to 1 nM) but does not depress acetylcholine release from motor nerve endings. Blocks nicotine-induced increase of intracellular Ca2+ in PC12 cells (IC50 = 310 nM), and prevents opening of nicotinic receptor-associated ion channels. Reconstitution experiments in Xenopus oocytes have shown the effects of α-bungarotoxin on neuronal nAChR to be highly specific for the α7-subtype (IC50 = 1.6 nM), but not for the α3β4-subtype (IC50 >3 μM).

Hazard

Nuerotoxic.

ALPHA-BUNGAROTOXIN Preparation Products And Raw materials

Raw materials

Preparation Products

ALPHA-BUNGAROTOXIN Suppliers

Global( 53)Suppliers
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Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21676 55 Inquiry
Shenzhen Nexconn Pharmatechs Ltd +86-755-89396905 +86-15013857715 China 10259 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
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Zhejiang Hangyu API Co., Ltd +8617531972939 China 2944 58 Inquiry
Hangzhou Beiputai Biopharmaceutical Co., Ltd 0571-85350119 13305819357 China 3793 58 Inquiry
Beijing Stronger Science Co., Ltd. 0531-88924771 15614660963 China 10624 58 Inquiry
ALPHA-BUNGAROTOXIN ALPHA-BUNGAROTOXIN, BUNGARUS MULTICINCTUS ALPHA-BUTX ALPHA-BGT A-BUNGAROTOXIN M.W. 7984.14 C338H529N97O105S11 H-ILE-VAL-CYS-HIS-THR-THR-ALA-THR-SER-PRO-ILE-SER-ALA-VAL-THR-CYS-PRO-PRO-GLY-GLU-ASN-LEU-CYS-TYR-ARG-LYS-MET-TRP-CYS-ASP-ALA-PHE-CYS-SER-SER-ARG-GLY-LYS-VAL-VAL-GLU-LEU-GLY-CYS-ALA-ALA-THR-CYS-PRO-SER-LYS-LYS-PRO-TYR-GLU-GLU-VAL-THR-CYS-CYS-SER-THR-ASP-LYS-CYS-ASN-PRO-HIS-PRO-LYS-GLN-ARG-PRO-GLY-OH BUNGARUS MULTICINCTUS TOXIN, ALPHA A-BUNGAROTOXIN FROM THE VENOM OF THE α-BuTX α-Bungarotoxin, Bungarus multicinctus - CAS 11032-79-4 - Calbiochem α-Bungotoxin α-Bungarotoxin TIANFU-CHEM - ALPHA-BUNGAROTOXIN 11032-79-4 C338H529N97O105S11 Acetylcholine receptor