ALPHA-BUNGAROTOXIN
- CAS No.
- 11032-79-4
- Chemical Name:
- ALPHA-BUNGAROTOXIN
- Synonyms
- α-BuTX;ALPHA-BGT;ALPHA-BUTX;α-Bungotoxin;A-BUNGAROTOXIN;α-Bungarotoxin;ALPHA-BUNGAROTOXIN;TIANFU-CHEM - ALPHA-BUNGAROTOXIN;M.W. 7984.14 C338H529N97O105S11;BUNGARUS MULTICINCTUS TOXIN, ALPHA
- CBNumber:
- CB1331318
- Molecular Formula:
- C50H70O14
- Molecular Weight:
- 895.0824
- MOL File:
- 11032-79-4.mol
- Modify Date:
- 2023/6/30 15:45:59
storage temp. | −20°C |
---|---|
solubility | Soluble in sterile water |
form | solid |
color | white |
Water Solubility | Soluble in water |
CAS DataBase Reference | 11032-79-4 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H312-H332 |
Precautionary statements | P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501 |
WGK Germany | 3 |
RTECS | QQ4495249 |
Toxicity | chicken,LD50,intramuscular,74ug/kg (0.074mg/kg),Toxicon. Vol. 7, Pg. 89, 1969. |
ALPHA-BUNGAROTOXIN price More Price(1)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 203980 | α-Bungarotoxin, Bungarus multicinctus - CAS 11032-79-4 - Calbiochem Blocks neuromuscular transmission by irreversible binding to motor end-plate acetylcholine receptor (Kd = 1 pM to 1 nM) but does not depress acetylcho | 11032-79-4 | 1MG | ₹17660 | 2022-06-14 | Buy |
Product number | Packaging | Price | Buy |
---|---|---|---|
203980 | 1MG | ₹17660 | Buy |
ALPHA-BUNGAROTOXIN Chemical Properties,Uses,Production
Chemical Properties
Single polypeptide weight; molecular weight of 8000.
Definition
A protein that binds specifically to acetylcholine receptors.
General Description
Blocks neuromuscular transmission by irreversible binding to motor end-plate acetylcholine receptor (Kd = 1 pM to 1 nM) but does not depress acetylcholine release from motor nerve endings. Blocks nicotine-induced increase of intracellular Ca2+ in PC12 cells (IC50 = 310 nM), and prevents opening of nicotinic receptor-associated ion channels. Reconstitution experiments in Xenopus oocytes have shown the effects of α-bungarotoxin on neuronal nAChR to be highly specific for the α7-subtype (IC50 = 1.6 nM), but not for the α3β4-subtype (IC50 >3 μM).
Hazard
Nuerotoxic.
ALPHA-BUNGAROTOXIN Preparation Products And Raw materials
Raw materials
Preparation Products
ALPHA-BUNGAROTOXIN Suppliers
Global( 53)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21676 | 55 | Inquiry |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10259 | 58 | Inquiry |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | China | 15395 | 58 | Inquiry |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | China | 35451 | 58 | Inquiry |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | China | 49999 | 58 | Inquiry |
Zhejiang Hangyu API Co., Ltd | +8617531972939 | China | 2944 | 58 | Inquiry |
Hangzhou Beiputai Biopharmaceutical Co., Ltd | 0571-85350119 13305819357 | China | 3793 | 58 | Inquiry |
Beijing Stronger Science Co., Ltd. | 0531-88924771 15614660963 | China | 10624 | 58 | Inquiry |
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ALPHA-BUNGAROTOXIN
ALPHA-BUNGAROTOXIN, BUNGARUS MULTICINCTUS
ALPHA-BUTX
ALPHA-BGT
A-BUNGAROTOXIN
M.W. 7984.14 C338H529N97O105S11
H-ILE-VAL-CYS-HIS-THR-THR-ALA-THR-SER-PRO-ILE-SER-ALA-VAL-THR-CYS-PRO-PRO-GLY-GLU-ASN-LEU-CYS-TYR-ARG-LYS-MET-TRP-CYS-ASP-ALA-PHE-CYS-SER-SER-ARG-GLY-LYS-VAL-VAL-GLU-LEU-GLY-CYS-ALA-ALA-THR-CYS-PRO-SER-LYS-LYS-PRO-TYR-GLU-GLU-VAL-THR-CYS-CYS-SER-THR-ASP-LYS-CYS-ASN-PRO-HIS-PRO-LYS-GLN-ARG-PRO-GLY-OH
BUNGARUS MULTICINCTUS TOXIN, ALPHA
A-BUNGAROTOXIN FROM THE VENOM OF THE
α-BuTX
α-Bungarotoxin, Bungarus multicinctus - CAS 11032-79-4 - Calbiochem
α-Bungotoxin
α-Bungarotoxin
TIANFU-CHEM - ALPHA-BUNGAROTOXIN
11032-79-4
C338H529N97O105S11
Acetylcholine receptor