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L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID

L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Structure
CAS No.
42438-90-4
Chemical Name:
L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
Synonyms
TCR;TNCA;L -CarL;H-TPI-OH;H-THNH(3)-OH;Lycoperodine 1;TNCA >=98% (HPLC);RARECHEM BK PT 0088;CYCLOMETHYLTRYPTOPHAN;Tryptophan Impurity M
CBNumber:
CB1395455
Molecular Formula:
C12H12N2O2
Molecular Weight:
216.24
MOL File:
42438-90-4.mol
Modify Date:
2023/4/23 13:52:06
Request For Quotation

L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Properties

Melting point 289 °C (dec.)(lit.)
Boiling point 485.0±45.0 °C(Predicted)
Density 1.377±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility soluble1.5mg/mL, clear (Solvent: 0.1N HCl:DMSO (1:1); warmed)
pka 2.28±0.20(Predicted)
form powder
color white to beige
optical activity [α]/D -57 to -67°, c = 1 (in MeOH:1N HCl (1:1))
InChIKey FSNCEEGOMTYXKY-JTQLQIEISA-N
CAS DataBase Reference 42438-90-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P233-P260-P261-P264-P271-P280-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HazardClass  IRRITANT

L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML1711 TNCA ≥98% (HPLC) 42438-90-4 10MG ₹5488.28 2022-06-14 Buy
Sigma-Aldrich(India) SML1711 TNCA ≥98% (HPLC) 42438-90-4 50MG ₹22299.5 2022-06-14 Buy
Product number Packaging Price Buy
SML1711 10MG ₹5488.28 Buy
SML1711 50MG ₹22299.5 Buy

L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Chemical Properties,Uses,Production

Chemical Properties

White to off-white powder

Biochem/physiol Actions

TNCA is a tryptophan derivative that binds the parathyroid Ca2+-sensing receptor (CaSR) extracellular domain (ECD) hinge region between two globular subdomains and acts as a high-affinity CaSR ligand (CaSRL) with co-agonist activity. TNCA is shown to potentiate both Mg++- and Ca++-evoked cellular calcium response (0.1-0.5 mM), as well as Mg++-evoked cellular ERK1/2 phosphorylation in CaSR-expressing HEK293 cells (0.5 mM). AC-265347 (Cat. No. SML0129), on the other hand, is a calcimimetic that functions as a CaSR agonist.

L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Suppliers

Global( 101)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +8618080483897 China 3777 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
BOC Sciences 16314854226; +16314854226 United States 19743 58 Inquiry
Nextpeptide Inc +86-0571-81612335 +8613336028439 China 19915 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Wuhan Han Sheng New Material Technology Co.，Ltd +8617798174412 China 2118 58 Inquiry
Wuhan BJM Pharm Inc +86-027-5234-1919 +8613545198479 China 677 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Supplier Advantage
A.J Chemicals 58
CHEMSWORTH 30
Chengdu Biopurify Phytochemicals Ltd. 58
AFINE CHEMICALS LIMITED 58
BOC Sciences 58
Nextpeptide Inc 58
TargetMol Chemicals Inc. 58
Wuhan Han Sheng New Material Technology Co.，Ltd 58
Wuhan BJM Pharm Inc 58
LEAPCHEM CO., LTD. 58

42438-90-4(L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID)Related Search:

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L-1,2,3,4-TETRAHYDRONORHARMANE-3-CARBOXYLIC ACID ETHYL ESTER HYDROCHLORIDE N-ALPHA-CARBOBENZOXY-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID H-TPI-OME
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L-TRYPTOLINE-3-CARBOXYLIC ACID H-TPI-OH H-THNH(3)-OH L-2,3,4-TETRAHYDRO-BETA-CARBOLINE-3-CARBOXYLIC ACID L-1,2,3,4-TETRAHYDRO-9H-PYRIDO[3,4-B]INDOLE-3-CARBOXYLIC ACID L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID 1,2,3,4-TETRAHYDRONORHARMAN-L-3-CARBOXYLIC ACID RARECHEM BK PT 0088 (S)-2,3,4,9-TETRAHYDRO-1H-PYRIDO[3,4-B]INDOLE-3-CARBOXYLIC ACID L-1,2,3,4-tetrahydronorharmane-3-carboxylic acid L-1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole-3-carb 2,3,4,9-Tetrahydro-1H-β-carboline-3-carboxylic acid (3S)-1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid (3S)-1,2,3,4-Tetrahydro-β-carboline-3α-carboxylic acid (3S)-2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indole-3α-carboxylic acid (S)-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic acid Lycoperodine 1 (3S)-2,3,4,9-Tetrahydro-1H-beta-carboline-3-carboxylic acid L-1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid, L-Tryptoline-3-carboxylic acid, H-Tpi-OH, L-1,2,3,4-Tetrahydro-b-carboline-3-carboxylic acid (3S)-1,3,4,9-tetrahydro-$b-carbolin-2-ium-3-carboxylate (3S)-1,3,4,9-tetrahydropyrido[5,4-b]indol-2-ium-3-carboxylate (3S)-2,3,4,9-tetrahydro-1H-$b-carboline-3-carboxylic acid (3S)-2,3,4,9-tetrahydro-1H-pyrido[5,4-b]indole-3-carboxylic acid CYCLOMETHYLTRYPTOPHAN TCR (S)-1,2,3,4-Tetrahydronorharmane-3-carboxylic acid (3S)-1H,2H,3H,4H,9H-pyrido[3,4-b]indole-3-carboxylic acid TNCA 4-b]indole-3-carboxylic acid 4-Tetrahydro-9H-pyrido[3 4-Tetrahydro-b-carboline-3-carboxylic acid 9-Tetrahydro-1H-beta-carboline-3-carboxylic acid L -CarL 1H-Pyrido[3,4-b]indole-3-carboxylic acid, 2,3,4,9-tetrahydro-, (3S)- L-1,2,3,4-Tetrahydro-β-carbolin-3-carboxylic acid TNCA >=98% (HPLC) Tryptophan Impurity M 42438-90-4 2438-90-4 C12H12NO2 Phenylalanine analogs and other aromatic alpha amino acids