ARG-LYS-ARG-ALA-ARG-LYS-GLU

ARG-LYS-ARG-ALA-ARG-LYS-GLU Structure
CAS No.
82801-73-8
Chemical Name:
ARG-LYS-ARG-ALA-ARG-LYS-GLU
Synonyms
RKRARKE;PKG INHIBITOR;PKG Inhibitor,RKRARKE;PKG inhibitor peptide;PROTEIN KINASE G INHIBITOR;Alg-Lys-Arg-Ala-Arg-Lys-Glu;[ALA32]-HISTONE H2B (29-35);ARG-LYS-ARG-ALA-ARG-LYS-GLU;OUKSKNTVYYVIMZ-DUJSLOSMSA-N;H-ARG-LYS-ARG-ALA-ARG-LYS-GLU-OH
CBNumber:
CB1437223
Molecular Formula:
C38H74N18O10
Molecular Weight:
943.11
MOL File:
82801-73-8.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:00

ARG-LYS-ARG-ALA-ARG-LYS-GLU Properties

Density 1.50±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Solid
pka 3.16±0.10(Predicted)
color White to off-white
Water Solubility Soluble in water at 1mg/ml

SAFETY

Risk and Safety Statements

WGK Germany  3

ARG-LYS-ARG-ALA-ARG-LYS-GLU Chemical Properties,Uses,Production

Description

PKG inhibitor is a specific cGMP-dependent PKG inhibitor (Ki = 86 μM). This synthetic peptide is a nonphosphorylatable analog of a substrate corresponding to the serine-32 phosphorylation site in histone H2B. PKG inhibitor has been reported to block cGMP-dependent NMDA potentiation and nitric oxide-induced depression of GABA currents in cultured retinal amacrine cells.

Uses

A reversible substrate competitive inhibitor for protein kinase G. The sequence corresponds to a non-phosphorylatable analog of histone H2B.

ARG-LYS-ARG-ALA-ARG-LYS-GLU Preparation Products And Raw materials

Raw materials

Preparation Products

ARG-LYS-ARG-ALA-ARG-LYS-GLU Suppliers

Global( 75)Suppliers
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ARG-LYS-ARG-ALA-ARG-LYS-GLU: RKRARKE ARG-LYS-ARG-ALA-ARG-LYS-GLU H-ARG-LYS-ARG-ALA-ARG-LYS-GLU-OH CGMP DEPENDENT KINASE INHIBITOR PEPTIDE [ALA32]-HISTONE H2B (29-35) PROTEIN KINASE G INHIBITOR RKRARKE arginyl-lysyl-arginyl-alanyl-arginyl-lysyl-glutamic acid cGMP-Dependent Protein Kinase Inhibitor Peptide Alg-Lys-Arg-Ala-Arg-Lys-Glu PKG INHIBITOR OUKSKNTVYYVIMZ-DUJSLOSMSA-N L-Glutamic acid, L-arginyl-L-lysyl-L-arginyl-L-alanyl-L-arginyl-L-lysyl- PKG Inhibitor,RKRARKE PKG inhibitor peptide 82801-73-8 C38H74N18O10 Cell Signaling and Neuroscience Cell Biology BioChemical Protein Kinase G (PKG) Kinase/Phosphatase Biology Serine/Threonine Kinase Inhibitors Protein Kinase