STERIGMATOCYSTIN
- CAS No.
- 10048-13-2
- Chemical Name:
- STERIGMATOCYSTIN
- Synonyms
- NSC 204985;NSC 201423;,(3ar-cis)-;petiolubicin;STERIGMATOCYSTIN;STERIGMATOCYSTINE;Sterigmatocystin,98%;Sertindole Impurity 14;STERIGMATOCYSTIN USP/EP/BP;Sterigmatocystin solution
- CBNumber:
- CB1475014
- Molecular Formula:
- C18H12O6
- Molecular Weight:
- 324.28
- MOL File:
- 10048-13-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/25 18:01:00
| Melting point | 249-251℃ |
|---|---|
| Boiling point | 382.63°C (rough estimate) |
| Density | 1.2842 (rough estimate) |
| refractive index | 1.4800 (estimate) |
| Flash point | 6℃ |
| storage temp. | 2-8°C |
| solubility | Acetone: 5 mg/ml |
| form | powder |
| pka | 6.92±0.20(Predicted) |
| color | yellow |
| BRN | 53259 |
| LogP | 3.169 (est) |
| CAS DataBase Reference | 10048-13-2 |
| IARC | 2B (Vol. 10, Sup 7) 1987 |
| EPA Substance Registry System | Sterigmatocystin (10048-13-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H351 | |||||||||
| Precautionary statements | P201-P301+P310+P330 | |||||||||
| Hazard Codes | T,Xn,F | |||||||||
| Risk Statements | 25-40-36-20/21/22-11 | |||||||||
| Safety Statements | 36/37-45-16 | |||||||||
| RIDADR | UN 3462 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LV1750000 | |||||||||
| F | 10 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29329990 | |||||||||
| NFPA 704 |
|
STERIGMATOCYSTIN price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | S3255 | Sterigmatocystin powder, ≥98% (TLC) | 10048-13-2 | 1MG | ₹5499.1 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S3255 | Sterigmatocystin powder, ≥98% (TLC) | 10048-13-2 | 5MG | ₹27289.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 32986 | Sterigmatocystin solution ~50?μg/mL in acetonitrile, analytical standard | 10048-13-2 | 1ML | ₹31135.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 32609 | Sterigmatocystin reference material | 10048-13-2 | 5MG | ₹99308.55 | 2022-06-14 | Buy |
STERIGMATOCYSTIN Chemical Properties,Uses,Production
Description
Sterigmatocystin is a mycotoxin that has been found in Aspergillus. It is lethal to rats (LD50 = 60 mg/kg) and chick embryos (LD50s = 5-7 μg/embryo). Sterigmatocystin (100 and 1,000 ppb in drinking water) induces gastritis, as well as intestinal polyp formation and metaplasia in aged Mongolian gerbils. It induces formation of lung and liver adenomas and malignant lymphomas in newborn mice.
Chemical Properties
yellow needles or powder
Uses
Sterigmatocystin is a carcinogenic mycotoxin that is struturally related to Aflatoxin. Sterigmatocystin has been shown to inhibit RNA synthesis in rat liver nuclei.
Definition
ChEBI: An organic heteropentacyclic compound whose skeleton comprises a xanthene ring system ortho-fused to a dihydrofuranofuran moiety. The parent of the class of sterigmatocystins.
Hazard
Possible carcinogen; tumorigen; poison; mutagen; causes necrosis of the liver and kidney, and an inhibitory effect on orotic acid incorporation into nuclear RNA.
Safety Profile
Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Poison by ingestion and intraperitoneal routes. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Purification Methods
It crystallises from amyl acetate, Me2CO or EtOH and sublimes in vacuo. It has UV max at 208, 235, 249 and 329nm (log 4.28, 4.39, 4.44 and 4.12). [UV: Bullock et al. J Chem Soc 4179, 1962, UV, IR: Holker & Mulheirn J Chem Soc, Chem Commun 1576, 1576 1968, Birkinshaw & Hammady Biochem J 65 162 1957.] This mycotoxin induces bone marrow changes in mice [Curry et al. Mutation Res 137 111 1984]. [Beilstein 19/10 V 575.]
STERIGMATOCYSTIN Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | China | 9030 | 58 | Inquiry |
| BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
| Alfa Chemistry | United States | 24072 | 58 | Inquiry | |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | China | 33350 | 58 | Inquiry |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +86-19164747840 +86-13119157289 | China | 2969 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Wuhan Fortuna Chemical Co.,Ltd | +8618007136271 | China | 5639 | 58 | Inquiry |
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