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ISOPIMARIC ACID

ISOPIMARIC ACID Structure
CAS No.
5835-26-7
Chemical Name:
ISOPIMARIC ACID
Synonyms
isopimaricaci;Δ7,15-IsopiMaric Acid;7,15-IsopiMaradien-18-oic Acid;13β-Methyl-13-vinylpodocarp-7-en-18-oic acid;13-Methyl-17-norabieta-7,15-diene-18-oic acid;(-)-13β-Methyl-13-vinylpodocarp-7-en-15-oic Acid;1-phenanthrenecarboxylicacid,7-ethenyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahyd;7-ethenyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahydro-1,4a,7-trimethyl-1-phenanthrenecarboxylicaci;(1R,4aR,4bS,7S,10aR)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahydrophenanthrene-1-carboxylic acid;(1R,4aR,4bS,7S,10aR)-7-Ethenyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahydro-1,4a,7-triMethyl-1-phenanthrenecarboxylic Acid
CBNumber:
CB1503654
Molecular Formula:
C20H30O2
Molecular Weight:
302.45
MOL File:
5835-26-7.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:19

ISOPIMARIC ACID Properties

Melting point 160°
alpha D16 -3.6° (10.4% soln in 1:1 alcohol:chloroform)
Boiling point 383.47°C (rough estimate)
Density 1.0434 (rough estimate)
refractive index 1.4980 (estimate)
storage temp. -20°C
solubility DMSO: ~26 mg/mL
pka 4?+-.0.60(Predicted)
form solid
color white
Stability Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
EPA Substance Registry System Isopimaric acid (5835-26-7)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS09
Signal word  Warning
Hazard statements  H400
Precautionary statements  P273
RIDADR  UN 3077 9 / PGIII
WGK Germany  3

ISOPIMARIC ACID price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) I6783 Isopimaric Acid ≥98% (GC), powder 5835-26-7 5MG ₹11160.58 2022-06-14 Buy
Sigma-Aldrich(India) I6783 Isopimaric Acid ≥98% (GC), powder 5835-26-7 25MG ₹50228 2022-06-14 Buy
Product number Packaging Price Buy
I6783 5MG ₹11160.58 Buy
I6783 25MG ₹50228 Buy

ISOPIMARIC ACID Chemical Properties,Uses,Production

Uses

A potent novel activators of large-conductance Ca2+-activated K+ channel.

General Description

Isopimaric acid, a resin acid produced by conifer trees, is a tricyclic diterpene compound. High levels of isopimaric acid in the hepatocytes of the rainbow trout may impair calcium signalling machinery. Isopimaric acid is a potential big potassium (BK) channel opener.

Biochem/physiol Actions

Potent opener of large conductance calcium activated K+ (BK) channels.

ISOPIMARIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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1-phenanthrenecarboxylicacid,7-ethenyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahyd 7-ethenyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahydro-1,4a,7-trimethyl-1-phenanthrenecarboxylicaci 13-Methyl-17-norabieta-7,15-diene-18-oic acid 13β-Methyl-13-vinylpodocarp-7-en-18-oic acid (-)-13β-Methyl-13-vinylpodocarp-7-en-15-oic Acid (1R,4aR,4bS,7S,10aR)-7-Ethenyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahydro-1,4a,7-triMethyl-1-phenanthrenecarboxylic Acid 7,15-IsopiMaradien-18-oic Acid Δ7,15-IsopiMaric Acid (1R,4aR,4bS,7S,10aR)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahydrophenanthrene-1-carboxylic acid 1-Phenanthrenecarboxylic acid, 7-ethenyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahydro-1,4a,7-trimethyl-, (1R,4aR,4bS,7S,10aR)- isopimaricaci 5835-26-7 Activators Aliphatics Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals Monovalent Ion Channels Potassium Channel Modulators Voltage-gated Ion Channels