DEHYDROABIETYLAMINE

DEHYDROABIETYLAMINE Structure
CAS No.
1446-61-3
Chemical Name:
DEHYDROABIETYLAMINE
Synonyms
Leelamine;AMINE D;DEHYDROABIETHYLAMINE;((1R,4aS,10aR)-7-Isopropyl-1,4a-diMethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)MethanaMine;NSC 2955;55.0%(GC);Leelamine HCl;((1R,4aS,10aR);Water galbanum;Dehydrobietylamine
CBNumber:
CB1692875
Molecular Formula:
C20H31N
Molecular Weight:
285.47
MOL File:
1446-61-3.mol
MSDS File:
SDS
Modify Date:
2023/6/8 17:06:36

DEHYDROABIETYLAMINE Properties

Melting point 44.50℃
Boiling point 417.89°C (rough estimate)
Density 0.963±0.06 g/cm3 (20 ºC 760 Torr)
refractive index n20/D 1.546(lit.)
Flash point >230 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform, DMSO, Methanol
form White solid.
pka 10.13±0.29(Predicted)
color Pale Yellow
optical activity [α]20/D +56.1°, c = 2.4 in pyridine
BRN 3084620
CAS DataBase Reference 1446-61-3(CAS DataBase Reference)
EPA Substance Registry System Dehydroabietylamine (1446-61-3)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  TP8701000
10-23
HS Code  29214990
NFPA 704
1
2 0

DEHYDROABIETYLAMINE price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 105198 (+)-Dehydroabietylamine technical grade, 60% 1446-61-3 100G ₹9731.68 2022-06-14 Buy
TCI Chemicals (India) D1588 (+)-Dehydroabietylamine [Optical Resolving Agent] min. 90.0 % 1446-61-3 5G ₹5700 2022-05-26 Buy
TCI Chemicals (India) D1588 (+)-Dehydroabietylamine [Optical Resolving Agent] min. 90.0 % 1446-61-3 25G ₹14600 2022-05-26 Buy
TCI Chemicals (India) D1180 Dehydroabietylamine min. 55.0 % 1446-61-3 25G ₹2000 2022-05-26 Buy
TCI Chemicals (India) D1180 Dehydroabietylamine min. 55.0 % 1446-61-3 500G ₹8200 2022-05-26 Buy
Product number Packaging Price Buy
105198 100G ₹9731.68 Buy
D1588 5G ₹5700 Buy
D1588 25G ₹14600 Buy
D1180 25G ₹2000 Buy
D1180 500G ₹8200 Buy

DEHYDROABIETYLAMINE Chemical Properties,Uses,Production

Chemical Properties

clear yellow viscous liquid

Uses

Dehydroabiethylamine is a primary amine with high molecular weight; shows a strong antibiotic effect with a broad spectrum of activity against Staphylococcus p.a. (sic), Escherichia coli, Mycobacterium tuberculosis, and Candida albicans.

Biological Activity

CB 1 agonist. Displaces binding of [ 3 H]-SR141716A with an IC 50 value of 2.86 μ M.

Purification Methods

The crude base is purified by converting 2g of base in toluene (3.3mL) into the acetate salt by heating at 65-70o with 0.46g of AcOH, and the crystals are collected and dried (0.96g from two crops, m 141-143o). The acetate salt is dissolved in warm H2O, basified with aqueous NaOH and extracted with *C6H6. The dried extract (MgSO4) is evaporated in vacuum leaving a viscous oil which crystallises and can be distilled. [Gottstein & Cheney J Org Chem 30 2072 1965.] The picrate has m 234-236o (from aqueous MeOH), and the formate has m 147-148o (from heptane). [Beilstein 12 IV 3005.]

DEHYDROABIETYLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 235)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
GLR Innovations +91 9891111994 New Delhi, India 4542 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Sai Quest Syn. Ltd 91-40-23607444 Hyderabad, India 268 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21676 55 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29901 58 Inquiry
Xiamen AmoyChem Co., Ltd +86-592-6051114 +8618959220845 China 6387 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
SIMAGCHEM CORP +86-13806087780 China 17367 58 Inquiry
(+)-DEHYDROABIETYLAMINE DEHYDROABIETYLAMINE (+)-DEHYDROABIETHYLAMINE D(+)-DEHYDROABIETYLAMINE 1-Phenanthrenemethanamine, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, (1R,4aS,10aR)- 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, [1R-(1.alpha.,4a.beta.,10a.alpha.)]1-Phenanthrenemethanamine (1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl-1-phenanthrenemethanamine) NSC 2955 1-phenanthrenemethanamine,1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-met Dehydrobietylamine (1R)-(1,2,3,4,4a,9,10,10aα-Octahydro-7-isopropyl-1,4aβ-dimethylphenanthrene)-1α-methanamine (1R)-1,2,3,4,4a,9,10,10aα-Octahydro-1,4aβ-dimethyl-7-(1-methylethyl)-1α-phenanthrenemethanamine (1R)-1,2,3,4,4a,9,10,10aα-Octahydro-1,4aβ-dimethyl-7-(1-methylethyl)phenanthrene-1α-methanamine (1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-isopropyl-1-phenanthrenemethanamine Dehydroabietylamine,60%,tech. Dehydroabietylamine1,4a-Dimethyl-7-isopropyl-1,2,3,4,4a,9,10,10a-octahydro-1- phenanthrenemethylamine (d)-dehyroabiethylamine Leelamine hydrochloride DEHYDROABIETYLAMINE, TECH., 60% DehydroabietylamineTech60% LYLAMINE HYDROCHLORIDE (1R,4AS,10AR)-1,2,3,4,4A,9,10,10A-OCTAHYDRO-1-,4A-DIMETHYL-7-(1-METHYLETHYL)-1-PHENANTHRENEMETHANAMINE HYDROCHLORIDE 1,4A-DIMETHYL-7-ISOPROPYL-1,2,3,4,4A,9,10,10A-OCTAHYDRO-1-PHENANTHRENEMETHYLAMINE 1 4A-DIMETHYL-7-ISOPROPYL-1 2 3,4A 9 10 10A-OCTAHYDRO-1-PHENANTHRENE METHYLAMINE (1r-(1alpha,4abeta,10aalpha))-hylethyl) [1theta-(1alpha,4abeta,10aalpha)]-hylethyl) 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-,[1R-(1.alpha.,4a.beta.,10a.alpha.)]1-Phenanthrenemethanamine 13-isopropylpodocarpa-8,11,13-trien-15-amine 13-trien-15-amine,13-isopropyl-podocarpa-11 (1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1-,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine ,60% ((1S,4aS,10aR)-7-isopropyl-1,4a-diMethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)MethanaMine (+)DehyroabietylaMine (1R,4aS,10aR)-1-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-phenanthrenemethanamine DehydroabiethylaMine (>80%) (+)-Dehydroabietylamine technical grade, 60% Leelamine HCl (+)-Dehydroabietylamine  [Optical Resolving Agent] ((1R,4aS,10aR) -7-Isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl) (1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1,4adimethyl- 7-(1-methylethyl)-1-phenanthrenemethanamine,99%d.e. (+)-Dehydroabietylamine Leelamine free base (+)-Dehydroabietylamine[OpticalResolvingAgent]> 55.0%(GC) Dehydroabietylamine > (+)-Dehydroabietylamine [Optical Resolving Agent] (+)-Dehydroabiethylamine 1446-61-3 C20H31N DEHYDROABIETYLAMINE DEHYDROABIETHYLAMINE AMINE D Leelamine ((1R,4aS,10aR)-7-Isopropyl-1,4a-diMethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)MethanaMine Pyruvate dehydrogenase kinase,PDH kinase,Dehydroabiethylamine,Inhibitor,PDHK,Cannabinoid Receptor,inhibit Water galbanum 1446-61-3 C20H31N C20H31NHCl