Tylosin phosphate
- CAS No.
- 1405-53-4
- Chemical Name:
- Tylosin phosphate
- Synonyms
- TYLAN;Farmazin TB;Pharmasine TB;osin phosphate;Tylan 40 premix;Tylan 10 premix;ylosin phosphate;Einecs 215-779-4;TYLOSIN PHOSPHATE;TylosinPhosphate80%
- CBNumber:
- CB1705560
- Molecular Formula:
- C46H80NO21P
- Molecular Weight:
- 1014.11
- MOL File:
- 1405-53-4.mol
- Modify Date:
- 2024/8/29 17:54:24
| Melting point | >128°C (dec.) |
|---|---|
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Pale Yellow |
| Stability | Hygroscopic |
| InChIKey | NBOODGNJLRRJNA-DRHKFUGVNA-N |
| CAS DataBase Reference | 1405-53-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H317-H334 |
| Precautionary statements | P261-P272-P280-P284-P302+P352-P333+P313 |
| WGK Germany | 2 |
| RTECS | YP0625000 |
| Toxicity | Tylosin base and its salts were shown to be of low acute oral toxicity with LD50 values in excess 5000 mg/kg bw in the rat and mouse and greater than 800 mg/kg bw in the dog. |
Tylosin phosphate Chemical Properties,Uses,Production
Chemical Properties
Tylosin phosphate (TS) is a light yellow to yellow liquid substance with a characteristic odor.
Tylosin phosphate has an antibacterial effect mainly on Gram-positive bacteria and partly on Gramnegative bacteria and mycoplasma, and has a growth-promoting effect on pigs.
Uses
Tylosin phosphate is a pure-grade antibiotic that was designated as a feed additive as of July 24, 1976. It is used for prevention and control of chronic respiratory disease (CRD) in replacement pullets, broilers, increasing bodyweight and improvement of feed conversion rate in broilers, increasing egg production.
General Description
Tylosin phosphate is an antibacterial agent employed against mycoplasma organisms. It is only used in veterinary field and effective basically against gram positive bacteria, but also has efficacy against some spirochetes and gram negatives (except coliforms). Tylosin phosphate, marketed as Tylan 40 or Tylan 100 Type A medicated article, is approved for use in beef cattle to reduce the incidence of liver abscesses caused by Fusobacterium necrophorum and Arcanobacterium (Actinomyces) pyogenes.
Mechanism of action
Tylosin phosphate is an antibiotic of macrolide group which is produced by fermentation of a certain fungus. This antibiotic prevents protein synthesis by ribosomes and thus prevents bacterial growth, resulting in their death. Special mechanism of action of macrolides, besides stopping rapid growth of microorganisms prevents buildup of bacterial resistance.
Tylosin phosphate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Global Chemicals Limited | 91-33-22253262 | Kolkata, India | 35 | 58 | Inquiry |
| Mitushi Biopharma | 08046058050 | Ahmedabad, India | 47 | 58 | Inquiry |
| Uni-Chemie International | 91-22-28881114 | Maharashtra, India | 62 | 58 | Inquiry |
| Nakshatra Chemicals | 09819631316 | Mumbai, India | 162 | 58 | Inquiry |
| Aastrid International Pvt., Ltd. | 91-22-42552525 | Maharashtra, India | 113 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Medi Pharma Drug House | 91-22-61904500 (100 Lines) | Maharashtra, India | 81 | 58 | Inquiry |
| Gansai International | 91-40-27425615 | Andhra Pradesh, India | 159 | 58 | Inquiry |
| Cosmos Intenational | 91-22-28644685 | Maharashtra, India | 126 | 58 | Inquiry |
| Global Chem Asia Pacific | 91-9849161572 | Hyderabad, India | 255 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Global Chemicals Limited | 58 |
| Mitushi Biopharma | 58 |
| Uni-Chemie International | 58 |
| Nakshatra Chemicals | 58 |
| Aastrid International Pvt., Ltd. | 58 |
| Pharma Affiliates | 58 |
| Medi Pharma Drug House | 58 |
| Gansai International | 58 |
| Cosmos Intenational | 58 |
| Global Chem Asia Pacific | 58 |
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