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HYPOPHYLLANTHIN

HYPOPHYLLANTHIN Structure
CAS No.
33676-00-5
Chemical Name:
HYPOPHYLLANTHIN
Synonyms
NSC 619044;HYPOPHYLLANTIN;HYPOPHYLLANTHIN;(7R,8R,9S)-9-(3,4-dimethoxyphenyl)-4-methoxy-7,8-bis(methoxymethyl)-6,7,8,9-tetrahydrobenzo[g][1,3]benzodioxole;(7S,8S,9R)-9-(3,4-Dimethoxyphenyl)-6,7,8,9-tetrahydro-4-methoxy-7,8-bis(methoxymethyl)naphtho[1,2-d]-1,3-dioxole;Naphtho[1,2-d]-1,3-dioxole,9-(3,4-dimethoxyphenyl)-6,7,8,9-tetrahydro-4-methoxy-7,8-bis(methoxymethyl)-,(7S,8S,9R)-;Inhibitor,CD243,Pgp,inhibit,Hypophyllanthin,ABCB1,P-glycoprotein,P-gp,Cluster of differentiation 243,Multidrug resistance protein 1,MDR1
CBNumber:
CB1716924
Molecular Formula:
C24H30O7
Molecular Weight:
430.49
MOL File:
33676-00-5.mol
Modify Date:
2024/8/15 16:24:08

HYPOPHYLLANTHIN Properties

Melting point 129-130℃
Boiling point 511.1±50.0 °C(Predicted)
Density 1.158
storage temp. 4°C, protect from light
solubility ≤0.2mg/ml in ethanol;10mg/ml in DMSO;30mg/ml in dimethyl formamide
form crystalline solid
color White to off-white
LogP 3.770 (est)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Hazard Codes  Xn
Risk Statements  22
NFPA 704
0
2 0

HYPOPHYLLANTHIN price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 75142 Hypophyllanthin analytical standard 33676-00-5 10MG ₹36891.6 2022-06-14 Buy
Product number Packaging Price Buy
75142 10MG ₹36891.6 Buy

HYPOPHYLLANTHIN Chemical Properties,Uses,Production

Description

Hypophyllanthin is an active principle of P. amarus, a plant studied for its potential to treat hepatotoxicity. In Caco-2 cells 100 μM hypophyllanthin has been shown to reversibly inhibit P-glycoprotein (also known as multidrug resistance protein 1 (MDR1)) function without effect on MDR2 activity.

Uses

Hypophyllanthin can be used to study the modulation of NSAID-induced, ER stress-mediated apoptosis in Caco-2 cells by different polyphenolic antioxidants.

HYPOPHYLLANTHIN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 77)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Natural Remedies Pvt Ltd +91 (80) 4020-9999 New Delhi, India 110 50 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Natural Remedy Private Limited 09019202423 Karnataka, India 17 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-81138252 +86-18789408387 China 3958 58 Inquiry
Chengdu Greenpure Biopharma CO.,Ltd 18283602253; +8618283602253 China 953 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29899 58 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +8618080483897 China 3772 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry

HYPOPHYLLANTHIN Spectrum

HYPOPHYLLANTHIN HYPOPHYLLANTIN (7S,8S,9R)-9-(3,4-Dimethoxyphenyl)-6,7,8,9-tetrahydro-4-methoxy-7,8-bis(methoxymethyl)naphtho[1,2-d]-1,3-dioxole NSC 619044 Naphtho[1,2-d]-1,3-dioxole,9-(3,4-dimethoxyphenyl)-6,7,8,9-tetrahydro-4-methoxy-7,8-bis(methoxymethyl)-,(7S,8S,9R)- (7R,8R,9S)-9-(3,4-dimethoxyphenyl)-4-methoxy-7,8-bis(methoxymethyl)-6,7,8,9-tetrahydrobenzo[g][1,3]benzodioxole Inhibitor,CD243,Pgp,inhibit,Hypophyllanthin,ABCB1,P-glycoprotein,P-gp,Cluster of differentiation 243,Multidrug resistance protein 1,MDR1 33676-00-5