CYCLIC AMP

CYCLIC AMP Structure
CAS No.
86594-35-6
Chemical Name:
CYCLIC AMP
Synonyms
CAMP;3:5-CAMP;CYCLIC AMP-3',5';3',5'-CYCLIC AMP;ADENOSINE CYCLOPHOSPHATE;ADENOSINE CYCLICPHOSPHATE;ADENOSINE 3'5'-MONOPHOSPHATE;ADENOSINE-3':5'-PHOSPHATE CYCLIC;ADENOSINE-3':5'-CYCLIC PHOSPHATE;ADENOSINE-3',5'-CYCLIC PHOSPHATE H2O
CBNumber:
CB1747869
Molecular Formula:
C10H12N5O6P
Molecular Weight:
329.21
MOL File:
86594-35-6.mol
Modify Date:
2023/4/23 13:52:06

CYCLIC AMP Properties

Melting point 260 °C (dec.)(lit.)
Boiling point 701.5±70.0 °C(predicted)
Density 2.47±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
storage temp. 2-8°C
solubility H2O: 10 mg/mL pH of aqueous solution is approx. 3.0. The sodium salt (A6885) is about 20×
pka 1.00±0.60(predicted)
form powder
color white
Stability Hygroscopic

SAFETY

Risk and Safety Statements

Hazard Codes  C
Risk Statements  34
Safety Statements  22-24/25
WGK Germany  3
RTECS  AU7357600
10-21

CYCLIC AMP Chemical Properties,Uses,Production

Enzyme inhibitor

This prototypical second messenger (FWfree-acid = 329.21 g/mol; lmax = 259 nm; eM = 15400 M–1cm–1; Abbreviation: 3’,5’-cyclic AMP, 3’,5’-cAMP, opr cAMP), the isolation of which in the late 1950s earned Earl Sutherland his share of the 1971 Nobel Prize in Medicine & Physiology, activates susceptible protein kinases in signal transduction cascades. Elevated cAMP concentrations also activate cyclicAMP-gated ion channels; Exchange Proteins Activated by cAMP (or EPAC), such as RAPGEF3; and popeye domain-containing proteins (or Popdc). While many enzymes are weakly inhibited by cAMP (with inhibition constants typically in the 0.1 mM range or above), the peak physiologic concentration of cAMP rarely exceeds 1020 μM. Target(s): phosphate-activated glutaminase; glyceraldehyde3-phosphate dehydrogenase, Ki = 0.11 mM for the yeast enzyme; choline kinase; Bacillus subtilis ribonuclease; NAD(P)+ transhydrogenase, AB-specific; phosphofructokinase, weakly inhibited; hexokinase; adenosine deaminase; NAD+ nucleosidase, or NADase; poly(ADP-ribose) glycohydrolase; GMP synthetase; 5-phosphoribosylamine synthetase, or ribose-5phosphate:ammonia ligase; tyrosyl-tRNA synthetase, weakly inhibited; adenylylsulfatase; CDP-diacylglycerol diphosphatase; nucleotide diphosphatase, weakly inhibited; ATP diphosphatase, slight inhibition; keratan sulfotransferase, weakly inhibited; adenosylhomocysteinase; 6-phospho-b-glucosidase; prenyldiphosphatase; CMP-N-acylneuraminate phosphodiesterase; 2’,3’-cyclic-nucleotide 3’-phosphodiesterase, or cCMP phosphodiesterase; 3’,5’-cyclic-GMP phospho-diesterase, or cGMP phosphodiesterase; sphingomyelin phosphodiesterase; phosphoprotein phosphatase; 5’-nucleotidase; acid phosphatase; diacylglycerol cholinephosphotransferase; ethanolaminephosphotransferase; glucose-1-phosphate adenylyltransferase; nucleoside diphosphate kinase; AMP:thymidine kinase; diacylglycerol kinase; nucleoside phosphotransferase; 1phosphatidylinositol 4-kinase; NAD+ kinase (63; procollagen glucosyltransferase64; chitin synthase, weakly inhibited; glycogen phosphorylase, weakly inhibited; luciferase, firefly (Photinus-luciferin 4-monooxygenase, ATP-hydrolyzing.

CYCLIC AMP Preparation Products And Raw materials

Raw materials

Preparation Products

CYCLIC AMP Suppliers

Global( 21)Suppliers
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Baoji Guokang Healthchem co.,ltd +8615604608665 15604608665 CHINA 9427 58 Inquiry
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SHANGHAI KEAN TECHNOLOGY CO., LTD. +8613817748580 China 40067 58 Inquiry
United States Biological 800.520.3011 or 781.639.5092 United States 6256 80 Inquiry
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Crescent Chemical Co., Inc. 631 348 0333 United States 4599 68 Inquiry
Nacalai Tesque, Inc. 81 75 251 1723 Japan 6048 75 Inquiry
Perkin Elmer Life Sciences Inc. 617 350 9263 United States 1296 86 Inquiry
Biolog Life Science Institute +49 421 591355 Germany 275 74 Inquiry
Spectrum Info. Ltd. 380 44 573 23 97 Ukraine 2742 53 Inquiry
(S)-CYCLIC 3' 5'-(HYDROGEN PHOSPHATE) ADENOSINE CAMP, ADENOSINE-3',5'-CYCLIC MONOPHOSPHATE CAMP CYCLIC AMP-3',5' ADENOSINE-3':5'-PHOSPHATE CYCLIC ADENOSINE-3',5'-CYCLOPHOSPHORIC ACID ADENOSINE 3'5'-MONOPHOSPHATE ADENOSINE-3':5'-CYCLIC PHOSPHATE ADENOSINE-3',5'-CYCLIC PHOSPHATE H2O (-)-ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE ADENOSINE 3'-,5'-CYCLIC MONOPHOSPHATE ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE ADENOSINE-3',5'-CYCLIC-MONOPHOSPHORIC ACID ADENOSINE-3':5'-CYCLIC MONOPHOSPHORIC ACID ADENOSINE CYCLICPHOSPHATE ADENOSINE CYCLOPHOSPHATE Sp-cAMP,Adenosine, cyclic3',5'-[hydrogen (S)-phosphate] (9CI) 3:5-CAMP 3',5'-CYCLIC AMP Adenosine, cyclic 3',5'-[hydrogen (S)-phosphate] 86594-35-6 37837-81-9 Cell Biology Cell Signaling and Neuroscience Biochemicals and Reagents Analytical Standards Antibodies and Kits to Cyclic Nucleotides Antibodies to G Proteins and Cyclic Nucleotides Antibodies Analytical Chromatography Product Catalog BioChemical AA to AL Cyclic Nucleotide Metabolism Cyclic Nucleotides and Analogs Alphabetic Primary Antibodies Nucleosides, Nucleotides, Oligonucleotides Nucleotides G Proteins and Cyclic Nucleotides