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Cyclic AMP

Cyclic AMP Structure
CAS No.
60-92-4
Chemical Name:
Cyclic AMP
Synonyms
CAMP;ADENOSINE CYCLOPHOSPHATE;Acrasin;ADENOSINE CYCLPHOSPHATE;(4aR,6R,7R,7aS)-6-(6-Amino-9H-purin-9-yl)-2,7-dihydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide;3:5-CAMP;Cyclo-AMP;CYCLIC AMP;3',5'-cAMPH;Adenosine 3'
CBNumber:
CB8747868
Molecular Formula:
C10H12N5O6P
Molecular Weight:
329.21
MOL File:
60-92-4.mol
MSDS File:
SDS
Modify Date:
2024/11/13 21:11:14
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Cyclic AMP Properties

Melting point 260 °C (dec.)(lit.)
alpha -53.7 º (c=0.7,water)
Boiling point 56.12°C
Density 2.47±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility H2O: 10 mg/mL pH of aqueous solution is approx. 3.0. The sodium salt (A6885) is about 20×
form powder
pka 1.00±0.60(Predicted)
color white
Water Solubility 50 mg/mL
Merck 14,2708
BRN 52645
Stability Hygroscopic
NIST Chemistry Reference Adenosine 3',5'-cyclic monophosphate(60-92-4)
EPA Substance Registry System Adenosine, cyclic 3',5'-(hydrogen phosphate) (60-92-4)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P264b-P280-P301+P330+P331-P304+P340-P305+P351+P338-P310-P363-P403+P233-P501c
Hazard Codes  C,Xi
Risk Statements  34-36/37/38
Safety Statements  22-24/25-45-36/37/39-26-36
WGK Germany  3
RTECS  AU7357600
F  10-21
TSCA  Yes
HS Code  29349990
Toxicity oms-hmn:oth 100 mmol/L JIDEAE 65,52,75
NFPA 704
0
2 0

Cyclic AMP price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) A9501 Adenosine 3′,5′-cyclic monophosphate ≥98.5% (HPLC), powder 60-92-4 1G ₹28946.05 2022-06-14 Buy
Sigma-Aldrich(India) A9501 Adenosine 3′,5′-cyclic monophosphate ≥98.5% (HPLC), powder 60-92-4 5G ₹86188.65 2022-06-14 Buy
Sigma-Aldrich(India) A9501 Adenosine 3′,5′-cyclic monophosphate ≥98.5% (HPLC), powder 60-92-4 25G ₹291105.9 2022-06-14 Buy
TCI Chemicals (India) A2381 Adenosine 3',5'-Cyclic Monophosphate 60-92-4 1G ₹5600 2022-05-26 Buy
TCI Chemicals (India) A2381 Adenosine 3',5'-Cyclic Monophosphate 60-92-4 5G ₹17900 2022-05-26 Buy
Product number Packaging Price Buy
A9501 1G ₹28946.05 Buy
A9501 5G ₹86188.65 Buy
A9501 25G ₹291105.9 Buy
A2381 1G ₹5600 Buy
A2381 5G ₹17900 Buy

Cyclic AMP Chemical Properties,Uses,Production

Chemical Properties

White crystalline or Pale yellow powder; odorless. Slightly soluble in water, almost insoluble in ethanol or ether.

Uses

cAMP is used for intracellular signal transduction in many different organisms, conveying the cAMP-dependent pathway. Restoration of several morphological characteristics of normal fibroblasts in sarcoma cells when treated with adenosine-3': 5'-cyclic monophosphate. In the presence of adenosine 3':5'-cyclic monophosphate, protein kinase I dissociated into two subunits: a subunit binding adenosine 3':5'-cyclic monophosphate, and a catalytic subunit. Stimulation of calcium uptake in platelet membrane vesicles by adenosine 3',5'-cyclic monophosphate.

Definition

ChEBI: Cyclic AMP is a 3',5'-cyclic purine nucleotide having having adenine as the nucleobase. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is an adenyl ribonucleotide and a 3',5'-cyclic purine nucleotide. It is a conjugate acid of a 3',5'-cyclic AMP(1-).

General Description

Cyclic AMP is a second messenger molecule comprised of an adenine ribonucleotide bearing a phosphate group bound to the oxygen molecules at the 3' and 5' positions of the sugar moiety. Cyclic AMP, which is synthesized from ATP by the intracellular enzyme adenylate cyclase, modulates the activity of several hormone-dependent signal transduction pathways.

Safety Profile

Human mutation data reported.When heated to decomposition it emits toxic fumes ofPOx and NOx.

Synthesis

Cyclic AMP is synthesized from ATP by adenylate cyclase located on the inner side of the plasma membrane and anchored at various locations in the interior of the cell.[1] Adenylate cyclase is activated by a range of signaling molecules through the activation of adenylate cyclase stimulatory G (Gs)-protein-coupled receptors. Adenylate cyclase is inhibited by agonists of adenylate cyclase inhibitory G (Gi)-protein-coupled receptors. Liver adenylate cyclase responds more strongly to glucagon, and muscle adenylate cyclase responds more strongly to adrenaline.
cAMP decomposition into AMP is catalyzed by the enzyme phosphodiesterase.

Cyclic AMP Preparation Products And Raw materials

Raw materials

Moroxydine Dicyclohexylcarbodide or CDCC Styrene cation exchange resin Anhydrous pyridine Water pump
Ammonium bicarbonate Dicyclohexylcarbodiimide
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Preparation Products

6-Thioguanine INOSINE-3',5'-CYCLIC PHOSPHATE

Cyclic AMP Suppliers

Global( 550)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Otto Chemie Pvt. Ltd. +91 9820041841 Mumbai, India 5870 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6768 58 Inquiry
Triveni chemicals 08048762458 New Delhi, India 6088 58 Inquiry
Sisco Research Laboratories Pvt. Ltd. +91-22-4268 5800 Mumbai, India 4315 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
Anand Agencies 91-20-24454597 Maharashtra, India 2332 58 Inquiry
Sisco Resech Laboratories Private Limited +91-22-4268 5800 Mumbai, India 655 58 Inquiry
Biopharmacule Speciality Chemicals P Ltd (India) +91 40 6462 1866 Hyderabad, India 526 58 Inquiry
HangZhou RunYan Pharma Technology Co.,LTD. +8618882027439 China 302 58 Inquiry
Supplier Advantage
Otto Chemie Pvt. Ltd. 58
TCI Chemicals (India) Pvt. Ltd. 58
Triveni chemicals 58
Sisco Research Laboratories Pvt. Ltd. 58
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
Anand Agencies 58
Sisco Resech Laboratories Private Limited 58
Biopharmacule Speciality Chemicals P Ltd (India) 58
HangZhou RunYan Pharma Technology Co.,LTD. 58

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Cyclic AMP Spectrum

Cyclic AMP(60-92-4)MSCyclic AMP(60-92-4)1HNMRCyclic AMP(60-92-4)IR1Cyclic AMP(60-92-4)IR2Cyclic AMP(60-92-4)Raman

60-92-4(Cyclic AMP)Related Search:

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ADENOSINE-2':3'-CYCLIC MONOPHOSPHATE, SODIUM SALT 5'-Tosyladenosine ATP disodium salt
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adenosine 3',5'-phosphate monohydrate CAMP, ADENOSINE-3',5'-CYCLIC MONOPHOSPHATE CYCLIC AMP CYCLIC AMP-3',5' 5’-cyclicmonophosphate 6-(6-Amino-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide Adenosine 3',5'-cyclophosphate Adenosine 3',5'-phosphate Adenosine cyclic 3',5'-monophosphate Adenosine cyclic 3',5'-phosphate Adenosine cyclic monophosphate Adenosine, cyclic 3',5'-(hydrogen phosphate) adenosine,cyclic3’,5’-(hydrogenphosphate) adenosine3’,5’-cyclophosphate adenosine3’,5’-phosphate adenosinecyclic3’,5’-phosphate adenosinecyclicmonophosphate adenosinecyclicphosphate,cyclicamp Cyclic 3',5'-adenylic acid Cyclic adenosine 3',5'-monophosphate Cyclic adenosine 3',5'-phosphate cyclic3’,5’-(hydrogenphosphate)-adenosin ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE*HPL C MARKER ADENOSINE 3':5'-CYCLIC MONOPHOSPHATEFREE ACID (-)-ADENOSIN-3',5'-CYCLOPHOSPHORSAEURE 9 Adenosine 3',5'-hydrogen phosphate Adenosine 3'-,5'-cyclic monophosphate, 99+% Adenosine-3’,5’-cyclic phosphoric acid cyclic 3',5'-(hydrogen phosphate)Adenosine Adenosine-3'',5''-monophosphoric acid 3'-5' Cyclic adenosine monophosphate CYCLIC-AMP (ADENOSINE 3'', 5''-CYCLIC MONOPHOSPHATE) ADENOSINE-3,5-CYCLICMONOPHOSPHPRIC ACID extrapure for biochemistry 3μ,5μ-Cyclic AMP, Adenosine 3μ,5μ-cyclophosphate, cAMP Cyclic Adenosine Monophosphate (cAMP) cyclic3’,5’-adenylicacid cyclic3’,5’-amp cyclicadenosine3’,5’-phosphate (S)-CYCLIC 3' 5'-(HYDROGEN PHOSPHATE) ADENOSINE ADENOSINE CYCLICPHOSPHATE (-)-ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE ADENOSINE 3'-,5'-CYCLIC MONOPHOSPHATE ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE ADENOSINE-3',5'-CYCLIC-MONOPHOSPHORIC ACID ADENOSINE-3':5'-CYCLIC MONOPHOSPHORIC ACID ADENOSINE-3':5'-CYCLIC PHOSPHATE ADENOSINE-3',5'-CYCLIC PHOSPHATE H2O ADENOSINE-3',5'-CYCLOPHOSPHORIC ACID ADENOSINE 3'5'-MONOPHOSPHATE ADENOSINE-3':5'-PHOSPHATE CYCLIC 3:5-CAMP 3',5'-CYCLIC AMP 3',5'-Cyclic adenylphosphoric acid Adenosine-3',5'-cyclophosphate ,99% Adenosine 3',5'-Cyclic Monophosphate Hydrate Adenosin Cyclophosphate 3',5'-Cyclic AMP 3',5'-cAMP Adenosine 3',5'-cyclic Monophosphate Monohydrate