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ChemicalBook >제품 카탈로그 >생화학 공학>핵산 약물>3′,5′-사이클릭아데닐산

3′,5′-사이클릭아데닐산

3′,5′-사이클릭아데닐산
3′,5′-사이클릭아데닐산 구조식 이미지
카스 번호:
60-92-4
한글명:
3′,5′-사이클릭아데닐산
동의어(한글):
3′,5′-사이클릭아데닐산;아데노신사이클릭포스페이트
상품명:
Cyclic AMP
동의어(영문):
CAMP;ADENOSINE CYCLOPHOSPHATE;Acrasin;ADENOSINE CYCLPHOSPHATE;(4aR,6R,7R,7aS)-6-(6-Amino-9H-purin-9-yl)-2,7-dihydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide;3:5-CAMP;Cyclo-AMP;CYCLIC AMP;3',5'-cAMPH;Adenosine 3'
CBNumber:
CB8747868
분자식:
C10H12N5O6P
포뮬러 무게:
329.21
MOL 파일:
60-92-4.mol
MSDS 파일:
SDS

3′,5′-사이클릭아데닐산 속성

녹는점
260 °C (dec.)(lit.)
알파
-53.7 º (c=0.7,water)
끓는 점
56.12°C
밀도
2.47±0.1 g/cm3(Predicted)
저장 조건
-20°C
용해도
H2O: 10 mg/mL 수용액의 pH는 대략입니다. 3.0. 나트륨염(A6885)은 약 20×입니다.
물리적 상태
가루
산도 계수 (pKa)
1.00±0.60(Predicted)
색상
하얀색
수용성
50mg/mL
Merck
14,2708
BRN
52645
안정성
흡습성
NIST
Adenosine 3',5'-cyclic monophosphate(60-92-4)
EPA
Adenosine, cyclic 3',5'-(hydrogen phosphate) (60-92-4)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 C,Xi
위험 카페고리 넘버 34-36/37/38
안전지침서 22-24/25-45-36/37/39-26-36
WGK 독일 3
RTECS 번호 AU7357600
F 고인화성물질 10-21
TSCA Yes
HS 번호 29349990
독성 oms-hmn:oth 100 mmol/L JIDEAE 65,52,75
그림문자(GHS): GHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H314 피부에 심한 화상과 눈에 손상을 일으킴 피부부식성 또는 자극성물질 구분 1A, B, C 위험 GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
예방조치문구:
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P301+P330+P331 삼켰다면 입을 씻어내시오. 토하게 하려 하지 마시오.
P304+P340 흡입하면 신선한 공기가 있는 곳으로 옮기고 호흡하기 쉬운 자세로 안정을 취하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P310 즉시 의료기관(의사)의 진찰을 받으시오. 삼켰다면 즉시 의료기관(의사)의 도움을 받으시오.
P363 다시 사용전 오염된 의류는 세척하시오.
P403+P233 용기는 환기가 잘 되는 곳에 단단히 밀폐하여 저장하시오.
NFPA 704
0
2 0

3′,5′-사이클릭아데닐산 MSDS


3'-5' Cyclic adenosine monophosphate

3′,5′-사이클릭아데닐산 C화학적 특성, 용도, 생산

화학적 성질

White crystalline or Pale yellow powder; odorless. Slightly soluble in water, almost insoluble in ethanol or ether.

용도

cAMP is used for intracellular signal transduction in many different organisms, conveying the cAMP-dependent pathway. Restoration of several morphological characteristics of normal fibroblasts in sarcoma cells when treated with adenosine-3': 5'-cyclic monophosphate. In the presence of adenosine 3':5'-cyclic monophosphate, protein kinase I dissociated into two subunits: a subunit binding adenosine 3':5'-cyclic monophosphate, and a catalytic subunit. Stimulation of calcium uptake in platelet membrane vesicles by adenosine 3',5'-cyclic monophosphate.

정의

ChEBI: Cyclic AMP is a 3',5'-cyclic purine nucleotide having having adenine as the nucleobase. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is an adenyl ribonucleotide and a 3',5'-cyclic purine nucleotide. It is a conjugate acid of a 3',5'-cyclic AMP(1-).

일반 설명

Cyclic AMP is a second messenger molecule comprised of an adenine ribonucleotide bearing a phosphate group bound to the oxygen molecules at the 3' and 5' positions of the sugar moiety. Cyclic AMP, which is synthesized from ATP by the intracellular enzyme adenylate cyclase, modulates the activity of several hormone-dependent signal transduction pathways.

Safety Profile

Human mutation data reported.When heated to decomposition it emits toxic fumes ofPOx and NOx.

Synthesis

Cyclic AMP is synthesized from ATP by adenylate cyclase located on the inner side of the plasma membrane and anchored at various locations in the interior of the cell.[1] Adenylate cyclase is activated by a range of signaling molecules through the activation of adenylate cyclase stimulatory G (Gs)-protein-coupled receptors. Adenylate cyclase is inhibited by agonists of adenylate cyclase inhibitory G (Gi)-protein-coupled receptors. Liver adenylate cyclase responds more strongly to glucagon, and muscle adenylate cyclase responds more strongly to adrenaline.
cAMP decomposition into AMP is catalyzed by the enzyme phosphodiesterase.

3′,5′-사이클릭아데닐산 준비 용품 및 원자재

원자재

Moroxydine Dicyclohexylcarbodide or CDCC Styrene cation exchange resin Anhydrous pyridine Water pump 암모늄 비카보네이트 디사이클로헥실카르보디이미디

준비 용품

6-티오구아닌 이노신-3',5'-사이클릭인산염

3′,5′-사이클릭아데닐산 공급 업체

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HangZhou RunYan Pharma Technology Co.,LTD.
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Yantai Fenglu Fine Chemical Co. LTD 		+86-+undefined-008618315825527 +86-+undefined-008618315825527
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Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512
 info@tianfuchem.com China 21670 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075
 jack.li@time-chemicals.com China 1807 55

3′,5′-사이클릭아데닐산 관련 검색:

아데노신 삼인산 Na염 클린다마이신 인산염 아데노신 5'-아데닐산 아데노신 트라이포스파타아제 아데닌 3′,5′-사이클릭아데닐산 ADP phosphate ester starch Vidarabine monophosphate Dibutyryl adenosine cyclophosphate calcium SULPHOSUCCINIC ACID ESTER Adenosine 3',5'-cyclic monophosphate sodium salt Adenosine-5'-diphosphate disodium salt ADENOSINE 5'-TRIPHOSPHATE DISODIUM SAL& ADENOSINE 5'-DIPHOSPHATE MONOPOTASSIUM SALT Adenosine-5'-diphosphate trilithium salt ADENOSINE-2':3'-CYCLIC MONOPHOSPHATE, SODIUM SALT
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