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Vidarabine monophosphate

Vidarabine monophosphate Structure
CAS No.
29984-33-6
Chemical Name:
Vidarabine monophosphate
Synonyms
VIDARABINE PHOSPHATE;Vidarabine Monophasphate;Ara-A;cl-808;ARA-AMP;Vidarabine Impurity 1;ara-A 5'-monophosphate;vidarabinemonophosphate;Vidarabine Impurity 02;vidarabine-5’-monophosphate
CBNumber:
CB4404572
Molecular Formula:
C10H14N5O7P
Molecular Weight:
347.22
MOL File:
29984-33-6.mol
Modify Date:
2023/5/18 11:31:21

Vidarabine monophosphate Properties

Melting point 213 °C
Boiling point 798.5±70.0 °C(Predicted)
Density 2.32±0.1 g/cm3(Predicted)
storage temp. Store at 0°C
form Powder
pka 1.86±0.10(Predicted)
color White to Off-white
Water Solubility Soluble in water at 4mg/ml

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xn,T,Xi
Risk Statements  20/22-40-23/24/25-36/37/38
Safety Statements  37/39-24/25-45-36/37/39-22-36-26
RIDADR  2811
RTECS  AU6204000
HazardClass  6.1(a)
PackingGroup  II
HS Code  29400090
Toxicity LD50 ipr-rat: 1700 mg/kg DRFUD4 4,547,79
NFPA 704
0
1 0

Vidarabine monophosphate Chemical Properties,Uses,Production

Description

Vidarabine monophosphate, chemical name: 9-(5-O-Phosphono-beta-D-arabinofuranosyl)adenine is an anti deoxyribonucleic acid virus drug. IVidarabine triphosphate directly inhibits DNA polymerase and also acts as a chain terminator in DNA replication. An adenosine monophosphate analog in which ribose is replaced by an arabinose moiety. It is the monophosphate ester of VIDARABINE with antiviral and possibly antineoplastic properties.

Chemical Properties

Crystalline

Uses

Antiviral.

Application

Vidarabine monophosphate has broad-spectrum anti-virus effect and can inhibit a variety of DNA viruses. It is mainly used to treat chronic hepatitis B and other viral infections, such as herpes zoster, herpes simplex and genital herpes. It has quick effect and clear curative effect. It is a common drug for clinical anti-virus treatment.

Safety Profile

Moderately toxic byintraperitoneal route. When heated to decomposition itemits very toxic fumes of POx and NOx.

Vidarabine monophosphate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 191)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21669 55 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29897 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 +8618813727289 China 5738 58 Inquiry
Nanjing Shizhou Biotechnology Co., Ltd +86-15850508050 +86-15850508050 China 323 58 Inquiry
SIMAGCHEM CORP +86-13806087780 China 17367 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418671 China 34571 58 Inquiry
ARA-AMP 9-BETA-D-ARABINOFURANOSYLADENINE-5'-MONOPHOSPHATE 9-BETA-D-ARABINOFURANOSYL-ADENINE-5'-MONOPHOSPHORIC ACID 9-BETA-D-ARABINOFURANOSYLADENINE MONOPHOSPHATE 9-(5-O-PHOSPHONO-BETA-D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE ADENINE-9-BETA-D-ARABINOFURANOSIDE-5'-MONOPHOSPHATE ADENINE-BETA-D-ARABINOFURANOSIDE-5'-PHOSPHATE 5’-arabinosyladeninemonophosphate 9-(5-o-phosphono-beta-d-arabinofuranosyl)-9h-purin-6-amin 9-(beta-d-arabinofuranosyl)adenine5’-(dihydrogenphosphate) 9-beta-d-arabinofuranosyl-adenin5’-(dihydrogenphosphate) Ara-AMP, 9-β-D-Arabinofuranosyladenine 5μ-monophosphate (2R,3S,4S,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate Adenine-9-beta-D-arabinofuranoside-5'-monophosphate,98% 9-(5-O-phosphono-β-D-arabinofuranosyl)adenine Ara-A Adenine-9-beta-D-arabinofuranoside-5zzhlxy-monophosphate 9-(b-D-Arabinofuranosyl)adenine 5'-monophosphate Adenine 9-β-D-arabinofuranoside 5′-monophosphate ammonium salt adeninearabinoside5’-monophosphate adeninearabinosidemonophosphate arabinosyladeninemonophosphate cl-808 vidarabine-5’-monophosphate vidarabinemonophosphate ADENINE 9-β-D-ARABINOFURANOSIDE 5''-MONOPHOSPHATE (9-β-D-ARABINOFURANOSYLADENINE 5''-MONOPHOSPHATE: ARA-AMP) adenine 9-beta-arabinofuranoside 5'-monophosphate Adenine-9-beta-D-arabinofuranoside-5 9-(5-O-phosphono-beta-D-arabinofuranosyl)adenine ADENINE 9-B-D-ARABINOFURANOSIDE5'-MONOPH OSPHATE FR 9-β-D-Arabinofuranosyladenine 5'-(dihydrogen phosphate) Adenine-9-β-D-arabinofuranoside-5’-monophosphate 9H-Purin-6-amine,9-(5-O-phosphono-b-D-arabinofuranosyl)- Vidarabine Impurity 02 [5-(6-aminopurin-9-yl)-3,4-dihydroxy-2-oxolanyl]methyl phosphate 9-β-D-adenosineabinofuranosyladenine 5'-monophosphate, free acid 9H-Purin-6-amine, 9-(5-O-phosphono-β-D-arabinofuranosyl)- Vidarabine Impurity 1 ((2R,3S,4S,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate ara-Adenosine-5'-monophosphate (ara-AMP) Vidarabine monophosphate USP/EP/BP 9-β-D-Arabinofuranosyl-Adenine-5'-Monophosphate 9-(5-O-phosphono-β-D-arabinofuranosyl)adenine 3-Diaminopropionic acid hydrochloride VIDARABINE PHOSPHATE Vidarabine Monophasphate ARA-AMP Powder USP Standard 9-beta-D-Arabinofuranosyladenine-5'-monophosphate Hydrate 9-beta-D-Arabinofuranosyladenine-5'-monophosphate Hydrate ara-A 5'-monophosphate 29984-33-6 29984-33-6