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noxytiolin

noxytiolin Structure
CAS No.
15599-39-0
Chemical Name:
noxytiolin
Synonyms
Gynaflex;Noxyflex S;noxytiolin;Noxythiolin;Noxytioline;Noxythioline;1-(Hydroxymethyl)-3-methylthiourea;(methylamino-λsup4sup-sulfanylidyne)methylamino]methanol
CBNumber:
CB1933871
Molecular Formula:
C3H8N2OS
Molecular Weight:
120.17
MOL File:
15599-39-0.mol
Modify Date:
2023/5/4 17:34:34

noxytiolin Properties

Melting point 88-90°
Boiling point 203.7±42.0 °C(Predicted)
Density 1.223±0.06 g/cm3(Predicted)
pka 13.45±0.10(Predicted)

SAFETY

Risk and Safety Statements

Toxicity LD50 orally in mice: >3 g/kg (Aebi, Hafstetter)

noxytiolin Chemical Properties,Uses,Production

Originator

Noxyflex,Geistlich,UK,1964

Manufacturing Process

400 g methyl thiourea and 2.5 g NaHCO3 are dissolved in 400 ml formaldehyde solution of 35% concentration. After having been left at ordinary temperature for 2 to 3 hours, the solution is adjusted with dilute HCl to pH 7 to 7.5. After the reaction mixture had been left overnight at 15°C some of the final product crystallized and was filtered off using a Buchner funnel. The mother liquor was concentrated by evaporation in vacuo at a bath-temperature of 30°C. The crystals obtained were again collected by filtration using a Buchner funnel and were combined with the first crystalline fraction and dried in vacuo at ordinary temperature. Yield of pure substance 400 g; melting point 84°C to 86°C.

Therapeutic Function

Antifungal

noxytiolin Preparation Products And Raw materials

Raw materials

Preparation Products

noxytiolin Suppliers

Global( 9)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
3B Scientific Corporation 847 281 9822 United States 6971 56 Inquiry
CHEMICAL LAND21 82- 2 -783 - 8063 South Korea 6315 74 Inquiry
3B Scientific Corporation 847.281.9822 United States 6744 47 Inquiry
2A PharmaChem USA (630) 737-0988 United States 6148 39 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
Leancare Ltd. +33 962096793 United Kingdom 6460 42 Inquiry
Shaanxi Dideu Newmaterial Co., Ltd. 029-87576359 15353716720 China 10010 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 23962 58 Inquiry
noxytiolin Noxythiolin 1-(Hydroxymethyl)-3-methylthiourea Gynaflex Noxyflex S Noxytioline (methylamino-λsup4sup-sulfanylidyne)methylamino]methanol Noxythioline 15599-39-0 C3H8N2OS