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N-Boc-4-piperidinemethanol

N-Boc-4-piperidinemethanol Structure
CAS No.
123855-51-6
Chemical Name:
N-Boc-4-piperidinemethanol
Synonyms
TERT-BUTYL 4-(HYDROXYMETHYL)PIPERIDINE-1-CARBOXYLATE;N-BOC-piperidine-4-methanol;BOC-PIC(4)-OL;BUTTPARK 75\50-52;N-Boc-4-piperidineMe;Boc-4-Piperidine methanol;N-BOC-piperidin-4-Methanol;N-BOC-4-PIPERIDINEMETHANOL;BOC-ISONICOT(HEXAHYDRO)-OL;1-BOC-4-PIPERIDINEMETHANOL
CBNumber:
CB2100290
Molecular Formula:
C11H21NO3
Molecular Weight:
215.29
MOL File:
123855-51-6.mol
MSDS File:
SDS
Modify Date:
2025/4/9 20:10:46
Request For Quotation

N-Boc-4-piperidinemethanol Properties

Melting point 78-82 °C (lit.)
Boiling point 308.0±15.0 °C(Predicted)
Density 1.059±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Methanol
form Powder
pka 14.94±0.10(Predicted)
color White to brown
InChI InChI=1S/C11H21NO3/c1-11(2,3)15-10(14)12-6-4-9(8-13)5-7-12/h9,13H,4-8H2,1-3H3
InChIKey CTEDVGRUGMPBHE-UHFFFAOYSA-N
SMILES N1(C(OC(C)(C)C)=O)CCC(CO)CC1
CAS DataBase Reference 123855-51-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330
Hazard Codes  Xi
Safety Statements  24/25
WGK Germany  3
HazardClass  IRRITANT
HS Code  29339900
NFPA 704
1
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N-Boc-4-piperidinemethanol price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 556017 N-Boc-4-piperidinemethanol 97% 123855-51-6 5G ₹15046.75 2022-06-14 Buy
TCI Chemicals (India) B2364 1-(tert-Butoxycarbonyl)-4-piperidinemethanol min. 98.0 % 123855-51-6 1G ₹4500 2022-05-26 Buy
ALFA India ALF-H26650-06 1-Boc-4-piperidinemethanol, 97% 123855-51-6 5g ₹4875 2022-05-26 Buy
TCI Chemicals (India) B2364 1-(tert-Butoxycarbonyl)-4-piperidinemethanol min. 98.0 % 123855-51-6 5G ₹5700 2022-05-26 Buy
TCI Chemicals (India) B2364 1-(tert-Butoxycarbonyl)-4-piperidinemethanol min. 98.0 % 123855-51-6 25G ₹17200 2022-05-26 Buy
Product number Packaging Price Buy
556017 5G ₹15046.75 Buy
B2364 1G ₹4500 Buy
ALF-H26650-06 5g ₹4875 Buy
B2364 5G ₹5700 Buy
B2364 25G ₹17200 Buy

N-Boc-4-piperidinemethanol Chemical Properties,Uses,Production

Chemical Properties

White to light brown solid

Uses

N-Boc-4-piperidinemethanol is an important piperidine derivative, which can be used in organic synthesis and pharmaceutical intermediates, It may be used to synthesize:
methyl 5-methoxy-4-(1-methylpiperidin-4-ylmethoxy)-2-nitrobenzoate
N-Boc-4-piperidinecarboxaldehyde
[1-(tert-butoxycarbonyl)piperidin-4-yl]methyl methanesulfonate
Involved in the synthesis of bradycardic agents.

Application

N-Boc-4-piperidinemethanol is a curcumin analogue that binds to the epidermal growth factor receptor (EGFR) and prevents the binding of ligands. In vitro studies have shown that it can inhibit tumor growth and induce apoptosis in cancer cells. The drug is also capable of inhibiting the proliferation of normal cells, which may be due to its ability to recruit EGFR from outside the cell membrane. This process triggers signaling events that lead to cell death.

General Description

N-Boc-4-piperidinemethanol contains a tert-butyloxycarbonyl (t-BOC)-protecting group. It can be synthesized from 4-piperidinemethanol via reaction with di-tert-butyldicarbonate.

N-Boc-4-piperidinemethanol Preparation Products And Raw materials

Raw materials

Preparation Products

TERT-BUTYL 9-OXO-3-AZASPIRO[5.5]UNDECANE-3-CARBOXYLATE 4-(TOLUENE-4-SULFONYLOXY)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER N-TERT-BUTOXYCARBONYL-4-(4-TOLUENESULFONYLOXYMETHYL)PIPERIDINE 1-Boc-4-(aminomethyl)piperidine tert-butyl 4-(chloromethyl)piperidine-1-carboxylate
tert-butyl 4-(4-bromophenoxymethyl)piperidine-1-carboxylate
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N-Boc-4-piperidinemethanol Suppliers

Global( 498)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
BTC pharm India +918790379245 AndhraPradesh, India 1262 58 Inquiry
GLR Innovations +91 9891111994 New Delhi, India 4535 58 Inquiry
PURALABS +918985212143 Hyderabad, India 99 58 Inquiry
ALS INDIA LIFE SCIENCES +91-8977036379 +91-8977036379 Hyderabad, India 1878 58 Inquiry
VRUDDISRI PHARMA +91-9441446600 +91-9441446600 Hyderabad, India 70 58 Inquiry
BTC pharm India +918790379245 Telangana, India 412 58 Inquiry
JSK Chemicals +919879767970 Gujarat, India 3756 58 Inquiry
sgtlifesciences +91-9866957562 +91-9866957562 Telangana, India 73 58 Inquiry
TSK Lifesciences 91-9397306789 Hyderabad, India 246 58 Inquiry
Calyx Chemicals & Pharmaceuticals Limited +91-22-28571191 Mumbai, India 16 58 Inquiry
Supplier Advantage
BTC pharm India 58
GLR Innovations 58
PURALABS 58
ALS INDIA LIFE SCIENCES 58
VRUDDISRI PHARMA 58
BTC pharm India 58
JSK Chemicals 58
sgtlifesciences 58
TSK Lifesciences 58
Calyx Chemicals & Pharmaceuticals Limited 58

N-Boc-4-piperidinemethanol Spectrum

N-Boc-4-piperidinemethanol(123855-51-6)1HNMRN-Boc-4-piperidinemethanol(123855-51-6)IR

123855-51-6(N-Boc-4-piperidinemethanol)Related Search:

N-Boc-Piperidine-4-carboxylic acid methyl ester DROPERIDOL N-(tert-Butoxycarbonyl)-4-piperidone Haloperidol 2,2,6,6-Tetramethyl-4-piperidinol
PHENCYCLIDINE-D5 HYDROCHLORIDE tert-Butyl acetate tert-Butyl peroxyacetate 4-Piperidinemethanol tert-Butanol
1-Boc-2-piperidinemethanol,1-N-Boc-2-piperidinemethanol,1-TERT-BUTOXYCARBONYL-2-PIPERIDINEMETHANOL, N-BOC-2-PIPERIDINEMETHANOL 1-TERT-BUTOXYCARBONYL-3-PIPERIDINEMETHANOL, N-BOC-3-PIPERIDINEMETHANOL,1-Boc-3-piperidinemethanol 1-Boc-4-(2-hydroxyethyl)piperidine N-BOC-4-Hydroxypiperidine tert-Butyl 4-methylenepiperidine-1-carboxylate
1-Boc-4-cyanopiperidine N-Boc-(2R,3R,4S)-dolaproine TERT-BUTYL N-(2-HYDROXYETHYL)CARBAMATE
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1-N-BOC-4-HYDROXYMETHYL-PIPERIDINE 1-(TERT-BUTOXYCARBONYL)-4-(HYDROXYMETHYL)PIPERIDINE 1-(TERT-BUTOXYCARBONYL)-4-PIPERIDINEMETHANOL TERT-BUTYL 4-(HYDROXYMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE N-T-BUTOXYCARBONYL-HEXAHYDROISONICOTINOL N-T-BUTOXYCARBONYL-4-HYDROXYMETHYL-PIPERIDINE N-T-BUTOXYCARBONYL-4-PIPECOLINOL N-T-BUTOXYCARBONYL-4-PIPERIDINEMETHANOL N-(TERT-BUTOXYCARBONYL)-4-(HYDROXYMETHYL)PIPERIDINE N-(TERT-BUTOXYCARBONYL)-4-PIPERIDINEMETHANOL 1-Boc-4-(hydroxymethyl)piperidine 1-Boc-4-piperidinemethanol 1-(tert-Butoxycarbonyl)-4-(hydroxymethyl)piperidine N-Boc-4-piperidineMe 1-piperidinecarboxylic acid, 4-(hydroxymethyl)-, 1,1-dimet N-Boc-4-piperidinemethanol ,97% N-Boc-4-piperidinemethanol,N-tert-Butyloxycarbonyl-4-piperidinemethanol 4-(Hydroxymethyl)piperidine, N-BOC protected 97% 1-Boc-4-(hydroxymethyl)-p... tert-Butyl 4-(hydroxymethyl)piperidine-1-carboxylate, 1-(tert-Butoxycarbonyl)-4-(hydroxymethyl)piperidine t-Butyl 4-(hydroxymethyl)piperidine-1-carboxylate tert-butyl 4-(hydroxyMethyl)piperidin-1-carboxylate N-BOC-piperidin-4-Methanol N-Boc-4-piperidineMethanol, 95+% N - bok - 4 - piperidine Methanol 1-Boc-4-piperidinemethanol Synonyms N-tert-Butyloxycarbonyl-4-piperidinemethanol N-Boc-4-piperidinemethanol 97% 1,1-Dimethylethyl 4-(hydroxymethyl)-1-piperidinecarboxylate n-tert-butyloxycarbonyl-4-piperidinemethanol N-BOC-4-HYDROXYLMETHYLENE-PIPERIDINE N-BOC-4-HYDROXYMETHYLPIPERIDINE N-BOC-4-PIPERIDINEMETHANOL 1-N-Boc-4-piperidinemethanol tert-Butyl 4-(hydroxymethyl)-1-piperidinecarboxylate 1-(TERT-BUTOXYCARBONYL)-4-PYRROLIDINEMETHANOL (1-Boc-Piperidin-4-yl)methanol 1-TERT-BUTOXYCARBONYL-4-PIPERIDINEMETHANOL, N-BOC-4-PIPERIDINEMETHANOL N-BOC-4-HYDROXYMETHYLPIPERDINE N-(tert-Butoxycarbonyl)-4-(Hydroxymethyl)piperidine, 98 % 1-Piperidinecarboxylic acid, 4-(hydroxymethyl)-, 1,1-dimethylethyl ester 1-Boc-4-Hyroxymethyl-Piperidine 4-Hydroxylmethyl-N-( tert-butylcarboxylate)piperidine BUTTPARK 75\50-52 BOC-PIC(4)-OL BOC-ISONICOT(HEXAHYDRO)-OL 4-HYDROXYMETHYL-1-TERT-BUTOXYCARBONYLPIPERIDINE 4-HYDROXYMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 4-(HYDROXYMETHYL)PIPERIDINE-N-BOC PROTECTED 1-BOC-4-(HYDROXYMETHYL)PIPERIDINE 1-BOC-4-PIPERIDINEMETHANOL tert-Butyl 4-(hydroxymethyl)-1 1-(tert-Butoxycarbonyl)-4-piperidinemethanol > Boc-4-Piperidine methanol N-Boc-4-piperidinyl alcohol N-Boc 4-piperdine methanol N-Boc-4-piperidinemethanol 123855-51-6 TERT-BUTYL 4-(HYDROXYMETHYL)PIPERIDINE-1-CARBOXYLATE N-BOC-piperidine-4-methanol 4-Hydroxymethyl-piperidin-1-carboxylic acid tert-butyl ester N-Boc-4-piperidinemethanol