ChemicalBook > Product Catalog >Pharmaceutical intermediates >N-Boc-4-piperidinemethanol

N-Boc-4-piperidinemethanol

CAS No.: 123855-51-6

Chemical Name:: N-Boc-4-piperidinemethanol

Synonyms: TERT-BUTYL 4-(HYDROXYMETHYL)PIPERIDINE-1-CARBOXYLATE;N-BOC-piperidine-4-methanol;BOC-PIC(4)-OL;BUTTPARK 75\50-52;N-Boc-4-piperidineMe;Boc-4-Piperidine methanol;N-BOC-piperidin-4-Methanol;N-BOC-4-PIPERIDINEMETHANOL;BOC-ISONICOT(HEXAHYDRO)-OL;1-BOC-4-PIPERIDINEMETHANOL

CBNumber:: CB2100290

Molecular Formula:: C11H21NO3

Molecular Weight:: 215.29

MOL File:: 123855-51-6.mol

MSDS File:: SDS

Modify Date:: 2024/7/2 14:09:54

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N-Boc-4-piperidinemethanol Properties

Melting point	78-82 °C (lit.)
Boiling point	308.0±15.0 °C(Predicted)
Density	1.059±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	soluble in Methanol
form	Powder
pka	14.94±0.10(Predicted)
color	White to brown
InChI	InChI=1S/C11H21NO3/c1-11(2,3)15-10(14)12-6-4-9(8-13)5-7-12/h9,13H,4-8H2,1-3H3
InChIKey	CTEDVGRUGMPBHE-UHFFFAOYSA-N
SMILES	N1(C(OC(C)(C)C)=O)CCC(CO)CC1
CAS DataBase Reference	123855-51-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319

Precautionary statements

P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Hazard Codes

Safety Statements

24/25

WGK Germany

HazardClass

IRRITANT

HS Code

29339900

NFPA 704

	1
2		0

N-Boc-4-piperidinemethanol price More Price(6)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	556017	N-Boc-4-piperidinemethanol 97%	123855-51-6	5G	₹15046.75	2022-06-14	Buy
TCI Chemicals (India)	B2364	1-(tert-Butoxycarbonyl)-4-piperidinemethanol min. 98.0 %	123855-51-6	1G	₹4500	2022-05-26	Buy
ALFA India	ALF-H26650-06	1-Boc-4-piperidinemethanol, 97%	123855-51-6	5g	₹4875	2022-05-26	Buy
TCI Chemicals (India)	B2364	1-(tert-Butoxycarbonyl)-4-piperidinemethanol min. 98.0 %	123855-51-6	5G	₹5700	2022-05-26	Buy
TCI Chemicals (India)	B2364	1-(tert-Butoxycarbonyl)-4-piperidinemethanol min. 98.0 %	123855-51-6	25G	₹17200	2022-05-26	Buy

Product number	Packaging	Price	Buy
556017	5G	₹15046.75	Buy
B2364	1G	₹4500	Buy
ALF-H26650-06	5g	₹4875	Buy
B2364	5G	₹5700	Buy
B2364	25G	₹17200	Buy

N-Boc-4-piperidinemethanol Chemical Properties,Uses,Production

Chemical Properties

White to light brown solid

Uses

N-Boc-4-piperidinemethanol is an important piperidine derivative, which can be used in organic synthesis and pharmaceutical intermediates, It may be used to synthesize:
methyl 5-methoxy-4-(1-methylpiperidin-4-ylmethoxy)-2-nitrobenzoate
N-Boc-4-piperidinecarboxaldehyde
[1-(tert-butoxycarbonyl)piperidin-4-yl]methyl methanesulfonate
Involved in the synthesis of bradycardic agents.

Application

N-Boc-4-piperidinemethanol is a curcumin analogue that binds to the epidermal growth factor receptor (EGFR) and prevents the binding of ligands. In vitro studies have shown that it can inhibit tumor growth and induce apoptosis in cancer cells. The drug is also capable of inhibiting the proliferation of normal cells, which may be due to its ability to recruit EGFR from outside the cell membrane. This process triggers signaling events that lead to cell death.

General Description

N-Boc-4-piperidinemethanol contains a tert-butyloxycarbonyl (t-BOC)-protecting group. It can be synthesized from 4-piperidinemethanol via reaction with di-tert-butyldicarbonate.

N-Boc-4-piperidinemethanol Preparation Products And Raw materials

Raw materials

Preparation Products

TERT-BUTYL 9-OXO-3-AZASPIRO[5.5]UNDECANE-3-CARBOXYLATE 4-(TOLUENE-4-SULFONYLOXY)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER N-TERT-BUTOXYCARBONYL-4-(4-TOLUENESULFONYLOXYMETHYL)PIPERIDINE 1-Boc-4-(aminomethyl)piperidine tert-butyl 4-(chloromethyl)piperidine-1-carboxylate

tert-butyl 4-(4-bromophenoxymethyl)piperidine-1-carboxylate

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N-Boc-4-piperidinemethanol Suppliers

Global( 489)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
BTC pharm India	+918790379245	AndhraPradesh, India	1269	58	Inquiry
GLR Innovations	+91 9891111994	New Delhi, India	4542	58	Inquiry
PURALABS	+918985212143	Hyderabad, India	99	58	Inquiry
Allchem Lifescience Pvt. Ltd	+919867655500	Gujarat, India	971	58	Inquiry
JSK Chemicals	+919879767970	Gujarat, India	3756	58	Inquiry
Vepan Pharmatech Pvt Ltd	+91-9908788828 +91-9966094448	Telangana, India	72	58	Inquiry
ALS INDIA LIFE SCIENCES	+91-8977036379 +91-8977036379	Hyderabad, India	1879	58	Inquiry
sgtlifesciences	+91-9866957562 +91-9866957562	Telangana, India	90	58	Inquiry
VRUDDISRI PHARMA	+91-9441446600 +91-9441446600	Hyderabad, India	70	58	Inquiry
Ami Organics Limited.	91-7573001269	Gujarat, India	120	58	Inquiry

Supplier	Advantage
BTC pharm India	58
GLR Innovations	58
PURALABS	58
Allchem Lifescience Pvt. Ltd	58
JSK Chemicals	58
Vepan Pharmatech Pvt Ltd	58
ALS INDIA LIFE SCIENCES	58
sgtlifesciences	58
VRUDDISRI PHARMA	58
Ami Organics Limited.	58

N-Boc-4-piperidinemethanol Spectrum

N-Boc-4-piperidinemethanol(123855-51-6)¹HNMR N-Boc-4-piperidinemethanol(123855-51-6)IR

123855-51-6(N-Boc-4-piperidinemethanol)Related Search:

N-Boc-Piperidine-4-carboxylic acid methyl ester DROPERIDOL N-(tert-Butoxycarbonyl)-4-piperidone Haloperidol 2,2,6,6-Tetramethyl-4-piperidinol

PHENCYCLIDINE-D5 HYDROCHLORIDE tert-Butyl acetate tert-Butyl peroxyacetate 4-Piperidinemethanol tert-Butanol

1-Boc-2-piperidinemethanol,1-N-Boc-2-piperidinemethanol,1-TERT-BUTOXYCARBONYL-2-PIPERIDINEMETHANOL, N-BOC-2-PIPERIDINEMETHANOL 1-TERT-BUTOXYCARBONYL-3-PIPERIDINEMETHANOL, N-BOC-3-PIPERIDINEMETHANOL,1-Boc-3-piperidinemethanol 1-Boc-4-(2-hydroxyethyl)piperidine N-BOC-4-Hydroxypiperidine tert-Butyl 4-methylenepiperidine-1-carboxylate

1-Boc-4-cyanopiperidine N-Boc-(2R,3R,4S)-dolaproine TERT-BUTYL N-(2-HYDROXYETHYL)CARBAMATE

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1-N-BOC-4-HYDROXYMETHYL-PIPERIDINE 1-(TERT-BUTOXYCARBONYL)-4-(HYDROXYMETHYL)PIPERIDINE 1-(TERT-BUTOXYCARBONYL)-4-PIPERIDINEMETHANOL TERT-BUTYL 4-(HYDROXYMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE N-T-BUTOXYCARBONYL-HEXAHYDROISONICOTINOL N-T-BUTOXYCARBONYL-4-HYDROXYMETHYL-PIPERIDINE N-T-BUTOXYCARBONYL-4-PIPECOLINOL N-T-BUTOXYCARBONYL-4-PIPERIDINEMETHANOL N-(TERT-BUTOXYCARBONYL)-4-(HYDROXYMETHYL)PIPERIDINE N-(TERT-BUTOXYCARBONYL)-4-PIPERIDINEMETHANOL 1-Boc-4-(hydroxymethyl)piperidine 1-Boc-4-piperidinemethanol 1-(tert-Butoxycarbonyl)-4-(hydroxymethyl)piperidine N-Boc-4-piperidineMe 1-piperidinecarboxylic acid, 4-(hydroxymethyl)-, 1,1-dimet N-Boc-4-piperidinemethanol ,97% N-Boc-4-piperidinemethanol,N-tert-Butyloxycarbonyl-4-piperidinemethanol 4-(Hydroxymethyl)piperidine, N-BOC protected 97% 1-Boc-4-(hydroxymethyl)-p... tert-Butyl 4-(hydroxymethyl)piperidine-1-carboxylate, 1-(tert-Butoxycarbonyl)-4-(hydroxymethyl)piperidine t-Butyl 4-(hydroxymethyl)piperidine-1-carboxylate tert-butyl 4-(hydroxyMethyl)piperidin-1-carboxylate N-BOC-piperidin-4-Methanol N-Boc-4-piperidineMethanol, 95+% N - bok - 4 - piperidine Methanol 1-Boc-4-piperidinemethanol Synonyms N-tert-Butyloxycarbonyl-4-piperidinemethanol N-Boc-4-piperidinemethanol 97% 1,1-Dimethylethyl 4-(hydroxymethyl)-1-piperidinecarboxylate n-tert-butyloxycarbonyl-4-piperidinemethanol N-BOC-4-HYDROXYLMETHYLENE-PIPERIDINE N-BOC-4-HYDROXYMETHYLPIPERIDINE N-BOC-4-PIPERIDINEMETHANOL 1-N-Boc-4-piperidinemethanol tert-Butyl 4-(hydroxymethyl)-1-piperidinecarboxylate 1-(TERT-BUTOXYCARBONYL)-4-PYRROLIDINEMETHANOL (1-Boc-Piperidin-4-yl)methanol 1-TERT-BUTOXYCARBONYL-4-PIPERIDINEMETHANOL, N-BOC-4-PIPERIDINEMETHANOL N-BOC-4-HYDROXYMETHYLPIPERDINE N-(tert-Butoxycarbonyl)-4-(Hydroxymethyl)piperidine, 98 % 1-Piperidinecarboxylic acid, 4-(hydroxymethyl)-, 1,1-dimethylethyl ester 1-Boc-4-Hyroxymethyl-Piperidine 4-Hydroxylmethyl-N-( tert-butylcarboxylate)piperidine BUTTPARK 75\50-52 BOC-PIC(4)-OL BOC-ISONICOT(HEXAHYDRO)-OL 4-HYDROXYMETHYL-1-TERT-BUTOXYCARBONYLPIPERIDINE 4-HYDROXYMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 4-(HYDROXYMETHYL)PIPERIDINE-N-BOC PROTECTED 1-BOC-4-(HYDROXYMETHYL)PIPERIDINE 1-BOC-4-PIPERIDINEMETHANOL tert-Butyl 4-(hydroxymethyl)-1 1-(tert-Butoxycarbonyl)-4-piperidinemethanol > Boc-4-Piperidine methanol N-Boc-4-piperidinyl alcohol N-Boc 4-piperdine methanol N-Boc-4-piperidinemethanol 123855-51-6 TERT-BUTYL 4-(HYDROXYMETHYL)PIPERIDINE-1-CARBOXYLATE N-BOC-piperidine-4-methanol 4-Hydroxymethyl-piperidin-1-carboxylic acid tert-butyl ester 123855-51-6