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Erythromycin A Enol Ether

Erythromycin A Enol Ether Structure
CAS No.
33396-29-1
Chemical Name:
Erythromycin A Enol Ether
Synonyms
EM 523;Isoniazid Impurity 16;Erythromycin impurity B;Erythromycin Impurity 5;Erythromycin impurity 05;Erythromycin A Enol Ether;Erythromycin A Enol EtherI;JFVYXJKGJMUGRG-POECJHBWSA-N;Erythromycin Estolate Impurity E;Erythromycin A enol ether, EvoPure
CBNumber:
CB21176304
Molecular Formula:
C37H65NO12
Molecular Weight:
715.91
MOL File:
33396-29-1.mol
Modify Date:
2023/9/4 15:51:00

Erythromycin A Enol Ether Properties

Melting point 133-1350C
Boiling point 791.6±60.0 °C(Predicted)
Density 1.20±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Solid
pka 13.45±0.70(Predicted)
color White to Pale Yellow
CAS DataBase Reference 33396-29-1

SAFETY

Risk and Safety Statements

WGK Germany  3

Erythromycin A Enol Ether price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 05238 Erythromycin A enol ether analytical standard 33396-29-1 5MG ₹49470.25 2022-06-14 Buy
Product number Packaging Price Buy
05238 5MG ₹49470.25 Buy

Erythromycin A Enol Ether Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Erythromycin A enol ether is a degradation product of erythromycin formed under acidic conditions by C6–OH internal attack on the C9 ketone to produce a cyclic enol ether. The rearrangement results in a loss of antibiotic activity. This single reaction was the prime driver for the development of second and third generation erythromycins. Erythromycin A enol ether is an important standard for stability studies.

Erythromycin A Enol Ether Preparation Products And Raw materials

Raw materials

Preparation Products

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Erythromycin A Enol Ether Spectrum

11-(4-Dimethylamino-3-hydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-5-ethyl-3,4-dihydroxy-9-(5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydro-pyran-2-yloxy)-2,4,8,10,12,14-hexamethyl-6,15-dioxa-bicyclo[10.2.1]pentadec-1(14)-en-7-one (6R)-6-Deoxy-9-deoxo-6,9-epoxy-8,9-didehydroerythromycin 6,9-Epoxy-8,9-didehydro-9-deoxo-6-deoxyerythromycin 6-Deoxy-9-deoxo-8,9-didehydro-6,9-epoxyerythromycin 6β,9-Epoxy-8,9-didehydro-9-deoxo-6-deoxyerythromycin 9-Deoxo-6-deoxy-6,9-epoxy-8,9-didehydroerythromycin Erythromycin A Enol Ether EM 523 Erythromycin impurity B JFVYXJKGJMUGRG-POECJHBWSA-N Erythromycin Impurity 5 Erythromycin EP Impurity E/Erythromycin A Enol Ether/(2R,3R,4S,5R,8R,9S,10S,11R,12R)-9-[(2,6-dideoxy-3- C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]- 5-ethyl-3,4-dihydroxy-2,4,8,10,12,14-hexamethyl- 11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylohexopyr Erythromycin Impurity 5(Erythromycin EP Impurity E) Erythromycin Impurit E:(erythromycin A enol ether) Erythromycin EP Impurity E (Erythromycin A Enol Ether) Erythromycin, 8,9-didehydro-9-deoxo-6-deoxy-6,9-epoxy- Isoniazid Impurity 16 Erythromycin A Enol EtherI Erythromycin Lactobionate EP Impurity E Inhibitor,inhibit,Acidic,Erythromycin A enol ether,degradation Erythromycin Estolate EP Impurity E Erythromycin Ethylsuccinate EP Impurity E Erythromycin Estolate Impurity E Erythromycin Stearate EP Impurity E Erythromycin impurity 05 Erythromycin A enol ether, EvoPure (2R,3R,4S,5R,8R,9S,10S,11R,12R)-9-[(2,6-dideoxy-3-C-methyl- 3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-5-ethyl-3,4-dihydroxy- 2,4,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)- β-D-xylohexopyranosyl]oxy]-6,15-dioxabicyclo[10.2.1]pentadec- 1(14)-en-7-one 33396-29-1 C37H65NO12 Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Chromatography Drugs&Metabolites Forensic and Veterinary Standards Neat CompoundsAnalytical Standards Pharmacology Standards Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals Various Metabolites and Impurities