Docarpamine

CAS No.: 74639-40-0

Chemical Name:: Docarpamine

Synonyms: TA 870;TA-8704;Tanadopa;Docarpamine;3,4-Bis[(ethoxycarbonyl)oxy]-N-(N-acetyl-L-methionyl)benzeneethanamine;4-{2-[(N-Acetyl-L-methionyl)amino]ethyl}-1,2-phenylenediethylbiscarbonate;(S)-2-(Acetylamino)-N-[3,4-bis(ethoxycarbonyloxy)phenethyl]-4-(methylthio)butanamide;Carbonic acid, 4-[2-[[(2S)-2-(acetylamino)-4-(methylthio)-1-oxobutyl]amino]ethyl]-1,2-phenylene diethyl ester;Carbonic acid, 4-[2-[[2-(acetylamino)-4-(methylthio)-1-oxobutyl]amino]ethyl]-1,2-phenylene diethyl ester, (S)-;Carbonic acid, C,C'-[4-[2-[[2-(acetylamino)-4-(methylthio)-1-oxobutyl]amino]ethyl]-1,2-phenylene] C,C'-diethyl ester

CBNumber:: CB21178560

Molecular Formula:: C21H30N2O8S

Molecular Weight:: 470.54

MOL File:: 74639-40-0.mol

Modify Date:: 2023/5/4 17:34:41

Request For Quotation

Docarpamine Properties

Melting point	85-90°; mp 105-108° (Nishiyama, 1992)
alpha	D20 -15.6° (c = 2 in methanol)
Boiling point	731.0±60.0 °C(Predicted)
Density	1.222±0.06 g/cm3(Predicted)
pka	14.51±0.46(Predicted)

SAFETY

Risk and Safety Statements

Toxicity	LD50 in male, female rats (mg/kg): 1000-1400, ~1000 s.c.; in rats, dogs (mg/kg): _>2000 orally (Nishiyama, 1992)

Docarpamine Chemical Properties,Uses,Production

Description

Docarpamine is a cardiostimulant with diuretic activity launched in Japan for the treatment of circulatory insufficiency. It is an orally effective peripheral dopamine prodrug that is well absorbed from the gastrointestinal tract and converted to dopamine in vivo, which exerts renal vasodilatory and natriuretic effects by activating renal dopamine (DA₁) receptors, and a positive inotropic effect by activating cardiac β1-receptors. It has been reported to be effective in treating patients with acute heart failure, shock and acute renal failure.

Uses

Docarpamine maybe a usefule alternative to intravenous dopamine after cardiac surgery.

Docarpamine Preparation Products And Raw materials

Raw materials

Preparation Products

Docarpamine Suppliers

Global( 11)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
RR Scientific LLC	+86-13917743231	United States	878	58	Inquiry
Lanospharma Laboratories Co.,Ltd	13440048448	China	6343	56	Inquiry
Hubei Guangao Biotechnology Co., Ltd	027-027-59223056 18162699093	China	9928	58	Inquiry
R.R Scientific, LLC.	15010167677	China	876	58	Inquiry
SHANGHAI HOHANCE CHEMICAL CO.,LTD	021-31115312 18217084087	China	141	62	Inquiry
Hubei Qifei Pharmaceutical Chemical Co., Ltd	027-027-59322506 18071128681	China	9978	58	Inquiry
Hubei Shishun Biotechnology Co. Ltd	027-59223025 15107168801	China	9912	58	Inquiry
TLC Pharmaceutical Standards Ltd.	18012923235	China	4793	58	Inquiry
Weifu (Shanghai) Pharmaceutical Technology Co., LTD	021-57609736 13524092974;	China	237	58	Inquiry

Supplier	Advantage
BOC Sciences	58
RR Scientific LLC	58
Lanospharma Laboratories Co.,Ltd	56
Hubei Guangao Biotechnology Co., Ltd	58
R.R Scientific, LLC.	58
SHANGHAI HOHANCE CHEMICAL CO.,LTD	62
Hubei Qifei Pharmaceutical Chemical Co., Ltd	58
Hubei Shishun Biotechnology Co. Ltd	58
TLC Pharmaceutical Standards Ltd.	58
Weifu (Shanghai) Pharmaceutical Technology Co., LTD	58

74639-40-0(Docarpamine)Related Search:

N-[2-(4-methoxyphenyl)ethyl]-2-(methylamino)acetamide Docarpamine CARBONIC ACID ETHYL ESTER M-TOLYL ESTER

Docarpamine Carbonic acid, 4-[2-[[(2S)-2-(acetylamino)-4-(methylthio)-1-oxobutyl]amino]ethyl]-1,2-phenylene diethyl ester Carbonic acid, 4-[2-[[2-(acetylamino)-4-(methylthio)-1-oxobutyl]amino]ethyl]-1,2-phenylene diethyl ester, (S)- TA 870 Tanadopa (S)-2-(Acetylamino)-N-[3,4-bis(ethoxycarbonyloxy)phenethyl]-4-(methylthio)butanamide 3,4-Bis[(ethoxycarbonyl)oxy]-N-(N-acetyl-L-methionyl)benzeneethanamine TA-8704 Carbonic acid, C,C'-[4-[2-[[2-(acetylamino)-4-(methylthio)-1-oxobutyl]amino]ethyl]-1,2-phenylene] C,C'-diethyl ester 4-{2-[(N-Acetyl-L-methionyl)amino]ethyl}-1,2-phenylenediethylbiscarbonate 74639-40-0 C21H30N2O8S