ACIFRAN

CAS No.: 72420-38-3

Chemical Name:: ACIFRAN

Synonyms: ACIFRAN;ay25712;Acifranum;4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylicaci;4,5-Dihydro-5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid;4,5-DIHYDRO-5-METHYL-4-OXO-5-PHENYL-2-FURANCARBOXYLIC ACID;5-Methyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxylic acid;2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-;(R,S)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid

CBNumber:: CB2121167

Molecular Formula:: C12H10O4

Molecular Weight:: 218.21

MOL File:: 72420-38-3.mol

Modify Date:: 2024/7/2 8:55:01

Request For Quotation

ACIFRAN Properties

Melting point	176°
Boiling point	378.4±42.0 °C(Predicted)
Density	1.343±0.06 g/cm3(Predicted)
storage temp.	Store at +4°C
solubility	Soluble in DMSO > 10 mM
form	Powder
pka	2.25±0.40(Predicted)
color	Off-white to light yellow

SAFETY

Risk and Safety Statements

Toxicity	LD50 orally in rats: 3 g/kg (Jirkovsky, 1982)

ACIFRAN Chemical Properties,Uses,Production

Uses

Antihyperlipopro-teinemic.

brand name

Reductol (Wyeth-Ayerst).

Biological Activity

Hypolipidaemic agent; more potent than nicotinic acid and clofibrate. Full and potent agonist at the human orphan GPCR HM74A/GPR109A and GPR109B (EC 50 values are 1.3? and 4.2 μ M respectively). In vivo, reduces serum triglycerides and circulating LDL-cholesterol without affecting liver weight or liver enzymes.

ACIFRAN Preparation Products And Raw materials

Raw materials

2H-Pyran-2,3,5(4H,6H)-trione, 6-methyl-6-phenyl-

Preparation Products

ACIFRAN Suppliers

Global( 38)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd.	+86-18521732826	China	48467	58	Inquiry
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd	18502726233; 18502726233	China	9486	58	Inquiry
Shanghai Easy CDMO Co.,Ltd	021-61734564	China	10010	58	Inquiry
Shaanxi Xihua Chemical Industry Co., Ltd	029-81122149 13992773979	China	5737	58	Inquiry
Wuhan Acumen Bio-Technology Co.,ltd	027-027-16602739303 16602739303	China	3001	58	Inquiry
Cayman Chemical Company	(800) 364-9897	United States	6618	81	Inquiry
Shanghai Rechem science Co., Ltd.	21-31433387 15618786686	China	2988	58	Inquiry
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	China	8740	58	Inquiry

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	58
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd	58
Shanghai Easy CDMO Co.,Ltd	58
Shaanxi Xihua Chemical Industry Co., Ltd	58
Wuhan Acumen Bio-Technology Co.,ltd	58
Cayman Chemical Company	81
Shanghai Rechem science Co., Ltd.	58
Shanghai Yifei Biotechnology Co. , Ltd.	58

ACIFRAN Spectrum

ACIFRAN(72420-38-3)¹HNMR

72420-38-3(ACIFRAN)Related Search:

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TERT-BUTOXY ACETIC ACID 2,3-Dihydrofuran 2,5-Dimethyl-3(2H)-furanone

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ay25712 ACIFRAN 4,5-DIHYDRO-5-METHYL-4-OXO-5-PHENYL-2-FURANCARBOXYLIC ACID (R,S)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid 4,5-Dihydro-5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid Acifranum 4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylicaci 5-Methyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxylic acid 2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl- 72420-38-3 Miscellaneous Compounds