METHIOTHEPIN MALEATE
- CAS No.
- 19728-88-2
- Chemical Name:
- METHIOTHEPIN MALEATE
- Synonyms
- RO 8-6837;metitepinmaleate;Metitepine maleate;METHIOTHEPIN MALEATE;f)thiepin,10,11-dihydro-8-methylthio-10-(4-methylpiperazino)-dibenzo(hyd;f)thiepin,10,11-dihydro-10-(4-methylpiperazino)-8-methylthio-dibenzo(hyd;1-(10,11-dihydro-8-methylthiodibenzo(b,f)thiepin-10-yl)-4-methyl-piperazin;8-methylthio-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepinmaleate;1-[10,11-DIHYDRO-8-(METHYLTHIO)DIBENZO[B,F]THIEPIN-10-YL]-4-METHYLPIPERAZINE MALEATE;1-Methyl-4-(8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine maleate
- CBNumber:
- CB2181680
- Molecular Formula:
- C24H28N2O4S2
- Molecular Weight:
- 472.62
- MOL File:
- 19728-88-2.mol
- Modify Date:
- 2023/6/8 9:03:09
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H311+H331-H402 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P273-P280-P301+P310-P321-P330-P302+P352-P304+P340-P311-P312-P361+P364-P403+P233-P405-P501 | |||||||||
| Toxicity | LD5O in mice (mg/kg): 51 i.v.; 94 orally (Jilek) | |||||||||
| NFPA 704 |
|
METHIOTHEPIN MALEATE Chemical Properties,Uses,Production
Uses
Methiothepin Maleate exhibits anticonvulsant property and it is able to suppress pentylenetetrazol induced fos expression in zebrafish. In addition, Methiothepin Maleate is a 5-HT antagonist.
Definition
ChEBI: A maleate salt obtained by reaction of methiothepin with one equivalent of maleic acid. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays ffinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively).
METHIOTHEPIN MALEATE Preparation Products And Raw materials
Raw materials
Preparation Products
METHIOTHEPIN MALEATE Suppliers
Global( 19)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | China | 42057 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
| TargetMol Chemicals Inc. | 15002134094 | China | 28091 | 58 | Inquiry |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | China | 41844 | 58 | Inquiry |
| Cayman Chemical Company | (800) 364-9897 | United States | 6618 | 81 | Inquiry |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | China | 9707 | 58 | Inquiry |
| BOC Sciences | USA | 0 | 65 | Inquiry | |
| BIOMOL INTERNATIONAL, LP | (800) 942-0430 | United States | 1503 | 77 | Inquiry |
| Service Chemical Inc. | 888-895-6920 | Germany | 6373 | 71 | Inquiry |
19728-88-2(METHIOTHEPIN MALEATE)Related Search:
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RO 8-6837
1-(10,11-dihydro-8-methylthiodibenzo(b,f)thiepin-10-yl)-4-methyl-piperazin
8-methylthio-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepinmaleate
f)thiepin,10,11-dihydro-10-(4-methylpiperazino)-8-methylthio-dibenzo(hyd
f)thiepin,10,11-dihydro-8-methylthio-10-(4-methylpiperazino)-dibenzo(hyd
metitepinmaleate
Dibenzo(B,F)thiepin, 10,11-dihydro-10-(4-methylpiperazino)-8-methylthio-, hydrogen maleate
Dibenzo(B,F)thiepin, 10,11-dihydro-8-methylthio-10-(4-methylpiperazino)-, hydrogen maleate
Metitepine maleate
Piperazine, 1-(10,11-dihydro-8-methylthiodibenzo(B,F)thiepin-10-yl)-4-methyl-, maleate (1:1)
1-[10,11-DIHYDRO-8-(METHYLTHIO)DIBENZO[B,F]THIEPIN-10-YL]-4-METHYLPIPERAZINE MALEATE
METHIOTHEPIN MALEATE
Piperazine, 1-[10,11-dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methyl-, (2Z)-2-butenedioate (1:1)
1-Methyl-4-(8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine maleate
19728-88-2