RS 23597-190 HYDROCHLORIDE

RS 23597-190 HYDROCHLORIDE Structure
CAS No.
149719-06-2
Chemical Name:
RS 23597-190 HYDROCHLORIDE
Synonyms
RS23597-190HCl;RS 23597-190 hydroch;RS 23597-190 >=98% (HPLC);RS 23597-190 HYDROCHLORIDE;RS 23597 190 hydrochloride,RS 23597190 hydrochloride;3-(PIPERIDIN-1-YL)PROPYL-4-AMINO-5-CHLORO-2-METHOXYBENZOATE HCL;3-(PIPERIDIN-1-YL)PROPYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE HYDROCHLORIDE;3-piperidin-1-ylpropyl 4-azanyl-5-chloro-2-methoxy-benzoate hydrochloride;3-(piperidine-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride;4-amino-5-chloro-2-methoxy-benzoic acid 3-piperidinopropyl ester hydrochloride
CBNumber:
CB2242093
Molecular Formula:
C16H24Cl2N2O3
Molecular Weight:
363.28
MOL File:
149719-06-2.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:03

RS 23597-190 HYDROCHLORIDE Properties

storage temp. Sealed in dry,2-8°C
solubility Water:36.33(Max Conc. mg/mL);100.0(Max Conc. mM)
form Powder
color White to off-white
Water Solubility Soluble to 100 mM in water

RS 23597-190 HYDROCHLORIDE price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML1909 RS 23597-190 ≥98% (HPLC) 149719-06-2 5MG ₹10619.33 2022-06-14 Buy
Product number Packaging Price Buy
SML1909 5MG ₹10619.33 Buy

RS 23597-190 HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

RS 23597-190 Hydrochloride is a selective and competitive SR-4 and 5-HT4 receptor antagonist.

Biological Activity

A high affinity, selective competitive antagonist at 5-HT 4 receptors.

Biochem/physiol Actions

RS 23597-190 is a high affinity 5-HT4-selective antagonist with in vitro and in vivo efficacy. RS 23597-190 is a 4-amino-5-chloro-2-methoxybenzoate that antagonizes 5-HT-mediated relaxation of carbachol-contracted rat oesphageal muscularis mucosae ex vivo (pA2 = 7.5) and prevents 5-HT-induced tachycardia (tachyarrhythmia) of anaesthetized micropigs in vivo (6 mg/kg RS 23597-190 and 3-10 μ/kg 5-HT via i.v.) by targeting 5-HT4 with high affinity (pKB = 7.8) and selectivity, while exhibiting no efficacy against 5-methoxytryptamine-mediated 5-HT3 activation in guinea-pig ileum and displaying much reduced or little affinity toward 5-HT3 (pKi = 5.7/mouse NG108-15 cells and pKB <5/guinea-pig ileum), dopamine receptors (pKi <4/D1 & <3/D2), muscarinic receptors (pKi <4.5 toward M1/2/3/4), 5-HT1A & 5-HT2 (pKi <5.2).

RS 23597-190 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

RS 23597-190 HYDROCHLORIDE Suppliers

Global( 34)Suppliers
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TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Beijing Bolide Biotechnology Co., Ltd. 010-51653916 CHINA 6172 58 Inquiry
Shanghai Weiwei Biological Technology Co., Ltd. 021-55669583 18616258598 CHINA 4398 58 Inquiry
Qingdao Jieshikang Biotechnology Co., Ltd. 4009025885 18754289606 CHINA 4012 58 Inquiry
Shanghai Haoyang Biological Technology Co., Ltd. 021-54046790 15121098156 CHINA 2905 58 Inquiry
Shanghai Chaoyan Biotechnology Co., Ltd. 021-50840550 CHINA 6217 58 Inquiry
Beijing Fubo Biotechnology Co., Ltd. 010-57263844 13260236521 CHINA 6039 58 Inquiry
3-(PIPERIDIN-1-YL)PROPYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE HYDROCHLORIDE RS 23597-190 HYDROCHLORIDE RS23597-190HCl 3-(piperidine-1-yl)propyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride 3-piperidin-1-ylpropyl 4-azanyl-5-chloro-2-methoxy-benzoate hydrochloride 4-amino-5-chloro-2-methoxy-benzoic acid 3-piperidinopropyl ester hydrochloride 3-(PIPERIDIN-1-YL)PROPYL-4-AMINO-5-CHLORO-2-METHOXYBENZOATE HCL 4-amino-5-chloro-2-methoxybenzoic acid 3-(1-piperidinyl)propyl ester hydrochloride RS 23597-190 >=98% (HPLC) RS 23597-190 hydroch Benzoic acid, 4-amino-5-chloro-2-methoxy-, 3-(1-piperidinyl)propyl ester, hydrochloride (1:1) 4-amino-5-chloro-2-methoxy-Benzoic acid 3-(1-piperidinyl)propyl ester hydrochloride (1:1) RS 23597 190 hydrochloride,RS 23597190 hydrochloride 149719-06-2 C16H24Cl2N2O3 C16H23ClN2O3HCl