2-Amino-5-bromo-3-(hydroxymethyl)pyridine
- CAS No.
- 335031-01-1
- Chemical Name:
- 2-Amino-5-bromo-3-(hydroxymethyl)pyridine
- Synonyms
- 2-broMo-4-ethoxypyriMidine;2-Amino-5-Bromo-3-(Hydroxymeth;2-Amino-5-bromopyridine-3-methanol;2-Amino-5-bromo-3-pyridinemethanol;3-Pyridinemethanol, 2-amino-5-bromo-;(2-AMINO-5-BROMO-3-PYRIDINYL)METHANOL;2-AMino-3-hydroxyMethyl-5-broMopyridine;(2-AMINO-5-BROMO-PYRIDIN-3-YL)-METHANOL;2-AMino-5-broMo-3-pyridineMethanol, 98+%;2-Amino-5-bromo-3-(hydroxymethyl)pyridine
- CBNumber:
- CB2248055
- Molecular Formula:
- C6H7BrN2O
- Molecular Weight:
- 203.04
- MOL File:
- 335031-01-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/4/27 16:27:43
| Melting point | 137-140°C |
|---|---|
| Boiling point | 343.5±37.0 °C(Predicted) |
| Density | 1.766±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Acetone, Ethyl Acetate, Methanol |
| pka | 13.16±0.10(Predicted) |
| form | Solid |
| color | Off-white to yellow |
| CAS DataBase Reference | 335031-01-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
2-Amino-5-bromo-3-(hydroxymethyl)pyridine price More Price(2)
2-Amino-5-bromo-3-(hydroxymethyl)pyridine Chemical Properties,Uses,Production
Uses
2-Amino-5-bromo-3-(hydroxymethyl)pyridine can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis
2-Amino-5-bromo-3-(hydroxymethyl)pyridineBromine (8.4 mL, 189.4 mmol) was added dropwise over 1 hour to a solution of 2- amino-3-(hydroxymethyl)pyridine (19.6 g, 157.8 mmol) in acetic acid (350 mL) at room temperature. The reaction mixture was then stirred overnight. After concentration to dryness, the residue was partitioned between a saturated solution of potassium carbonate (300 mL) and ethyl acetate (200 ml_). The aqueous layer was separated and extracted with ethyl acetate (2 x 200 ml_). The combined organic phases were washed with a saturated solution of sodium chloride (200 ml_), dried over sodium sulfate, filtered and concentrated to dryness. After trituration of the residue in pentane, the title product was obtained as a yellow solid (27.0 g, 84%).
2-Amino-5-bromo-3-(hydroxymethyl)pyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | CHINA | 21149 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10312 | 58 | Inquiry |
| Accela ChemBio Inc. | +1-858-6993322 | United States | 19447 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29825 | 58 | Inquiry |
| SIMAGCHEM CORP | +86-13806087780 | China | 17367 | 58 | Inquiry |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | China | 7122 | 58 | Inquiry |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23556 | 58 | Inquiry |
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