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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >DNA damage >PARP inhibitors >Veliparib

Veliparib

Veliparib Structure
CAS No.
912444-00-9
Chemical Name:
Veliparib
Synonyms
API VELIPARIB;100936;CS-301;A861695;Veliparib;NSC 737664;ABT-888 2HCl;Veliparib Base;VELIPARIBABT-888;Veliparib, >=98%
CBNumber:
CB22489643
Molecular Formula:
C13H16N4O
Molecular Weight:
244.29
MOL File:
912444-00-9.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:03
Request For Quotation

Veliparib Properties

Boiling point 579.0±40.0 °C(Predicted)
Density 1.274
storage temp. Store at -20°C
solubility insoluble in H2O; ≥10.6 mg/mL in EtOH with ultrasonic; ≥6.11 mg/mL in DMSO
form solid
pka 9.22±0.30(Predicted)
color White to off-white
CAS DataBase Reference 912444-00-9

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08,GHS07
Signal word  Warning
Hazard statements  H341-H373-H361-H302
Precautionary statements  P201-P202-P281-P308+P313-P405-P501-P260-P314-P501-P201-P202-P281-P308+P313-P405-P501-P264-P270-P301+P312-P330-P501

Veliparib Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

ABT-888 is a potent, orally bioavailable PARP-1/-2 inhibitor shown to potentiate DNA damaging agents. The ability to potentiate temozolomide (TMZ) and develop a biological marker for PARP inhibition was evaluated in vivo.

Definition

ChEBI: A benzimidazole substituted with a carbamoyl group at C-4 and a (2R)-2-methylpyrrolidin-2-yl moiety at C-2. It is a potent, orally bioavailable PARP inhibitor.

Veliparib Preparation Products And Raw materials

Raw materials

Preparation Products

Veliparib Suppliers

Global( 226)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Jigs Chemical ltd +919099003427 Gujarat, India 239 58 Inquiry
Bulat Pharmaceutical Pvt Ltd +91-8448085659 +91-8448085660 Haryana, India 123 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Bulat Pharmaceutical Private Limited 08048372574Ext 902 Haryana, India 37 58 Inquiry
shandong perfect biotechnology co.ltd +86-53169958659; +8618596095638 China 294 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20366 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
Shanghai Daken Advanced Materials Co.,Ltd +86-371-66670886 China 16221 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21677 55 Inquiry
Supplier Advantage
Jigs Chemical ltd 58
Bulat Pharmaceutical Pvt Ltd 58
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
Bulat Pharmaceutical Private Limited 58
shandong perfect biotechnology co.ltd 58
Henan Fengda Chemical Co., Ltd 58
Capot Chemical Co.,Ltd. 60
Shanghai Daken Advanced Materials Co.,Ltd 58
Henan Tianfu Chemical Co.,Ltd. 55

Veliparib Spectrum

Veliparib(912444-00-9)1HNMR

912444-00-9(Veliparib)Related Search:

Niraparib ABT-888 Chidamide Capecitabine 2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoic acid
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzonitrile Piperazine, 1-(cyclopropylcarbonyl)-, Monohydrochloride Bortezomib PF-01367338 MK-2206 2HCl
Talazoparib (BMN 673) PLX4032 Olaparib
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2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4- carboxamide 1H-Benzimidazole-4-carboxamide, 2-((2R)-2-methyl-2-pyrrolidinyl)- 2-((R)-2-Methylpyrrolidin-2-yl)-1H-benzimidazole-4-carboxamide A861695 2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide ABT-888 (Veliparib, NSC 737664) Veliparib(chiral) 2-[(R)-2-Methylpyrrolidin-2-yl]-1H-benziMidazole-4-carboxaMide 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benziMidazole-4-carboxaMide VELIPARIBABT-888 Veliparib ABT-888,Veliparib ABT-888 2HCl (S)-2-(2-Methylpyrrolidin-2-yl)-1H-benimidazole-4-carboxamide (R)-2-(2-Methylpyrrolidin-2-yl)-1H-benzo[d]iMidazole-4-carboxaMide NSC 737664 2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide Veliparib (ABT-888) Veliparib 2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide (R)-2-(2-Methylpyrrolidin-2-yl)-1H-benimidazole-4-carboxamide (VELIPARIB) Veliparib, >=98% ABT888 hydrochloride ABT-888;ABT 888;ABT888;NSC 737664 Veliparib Base Veliparib free base Veliparib 2-[(2R)-2 100936 2-[(2r)-2-methylpyrrolidin-2-yl]-1h-benzimidazole-4-carboxamide Veliparib or (R)-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole-4-carboxamide ABT888 (free base) CS-301 (R)-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole-7-carboxamide, Veliparib ABT 888 - Veliparib | A 861695 1H-Benzimidazole-7-carboxamide, 2-[(2R)-2-methyl-2-pyrrolidinyl]- Veliparib USP/EP/BP 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4-carboxami... base Veliparib base 2-(2-methylpyrrolidin-2-yl)-1H-1,3-benzodiazole-4-carboxamide TIANFU CHEM--Veliparib (ABT-888) API VELIPARIB (R)-2-(2-Methylpyrrolidin-2-yl)-1H-benzo[d]imidazole-7-carboxamide 912444-00-9 PARP Inhibitor Amines Heterocycles Inhibitors Intermediates & Fine Chemicals Pharmaceuticals API 912444-00-9