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Acotiamide Hydrochloride

Acotiamide Hydrochloride Structure
CAS No.
185104-11-4
Chemical Name:
Acotiamide Hydrochloride
Synonyms
Acotiamide-d6 HCl;Acotiamide hydrochloride;Acotiamide Impurity 14 HCl;Acotiamide dihydrochloride;Acotiamide Impurity 20 HCl;Acetylformamide hydrochloride;Acotiamide (hydrochloride) (Acotiamide Impurity);N-[2-[di(propan-2-yl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoy;N-[2-[Bisisopropylamino]-ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxamide HCl;N-[2-[Bis(1-methylethyl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxamide hydrochloride
CBNumber:
CB22510118
Molecular Formula:
C21H31ClN4O5S
Molecular Weight:
487.01
MOL File:
185104-11-4.mol
Modify Date:
2024/7/26 15:15:06
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Acotiamide Hydrochloride Properties

storage temp. Sealed in dry,Store in freezer, under -20°C

Acotiamide Hydrochloride Chemical Properties,Uses,Production

Description

Acotiamide Hydrochloride (YM-443, Z-338) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. It is a new orally active selective acetylcholinesterase inhibitor. Although the exact mechanism by which acotiamide exerts its effect has yet to be fully elucidated, this agent appears to inhibit acetylcholinesterase (AchE), an enzyme responsible for the breakdown of acetylcholine (Ach). Increased Ach concentrations lead to an improvement of gastric emptying and GI motility and eventually to a reduction of dyspepsia symptoms.

Biological Activity

Acotiamide hydrochloride is an orally active, selective and reversible acetylcholinesterase (AChE) inhibitor, with an IC50 of 1.79 μM. Acotiamide hydrochloride can enhance gastric contractility and accelerate delayed gastric emptying. Acotiamide hydrochloride has the potential for the research of functional dyspepsia involving gastric motility dysfunction and intestinal inflammatory.

Acotiamide Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Acotiamide Hydrochloride Suppliers

Global( 153)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Anant Pharmaceuticals Pvt Ltd +91-8550986868 +91-9485998001 Haryana, India 461 58 Inquiry
Metrochem API Private Limited +91-4069069999 +91-4069069999 Telangana, India 78 58 Inquiry
Hetero Drugs Limited +91-4023704923 +91-4023704923 Telangana, India 296 58 Inquiry
Vijaya Pharma And Life Science +91-8939866271 +91-8939866271 Tamil Nadu, India 320 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Metro Chem Api Private Limited 08048361349Ext 285 Hyderabad, India 9 58 Inquiry
Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd. +86-029-86185165 +8618629664246 China 1615 58 Inquiry
Anhui Dexinjia Biopharm Co., Ltd +86-531-82375818 +8615064153060 China 291 58 Inquiry
Supplier Advantage
Anant Pharmaceuticals Pvt Ltd 58
Metrochem API Private Limited 58
Hetero Drugs Limited 58
Vijaya Pharma And Life Science 58
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
SynZeal Research Pvt Ltd 58
Metro Chem Api Private Limited 58
Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd. 58
Anhui Dexinjia Biopharm Co., Ltd 58

185104-11-4(Acotiamide Hydrochloride)Related Search:

2-Aminothiazole-4-carboxylic acid Methyl 2-Aminothiazole-4-carboxylate Ethyl bromopyruvate AcotiaMide IMpurity 9 AcotiaMide Related CoMpound 6
Acotiamide Impurity 27 Acotiamide INT AcotiaMide related coMpound 2 AcotiaMide IMpurity 7 AcotiaMide iMpurity 5
Acotiamide Impurity 40 Acotiamide Impurity 30 Acotiamide Impurity 15 Acotiamide Hydrochloride AcotiaMide iMpurity 1
2,4,5-TRIHYDROXYBENZOIC ACID Acotiamide Impurity 10 HCl Acotiamide Impurity 21
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Acotiamide hydrochloride N-[2-[Bis(1-methylethyl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxamide hydrochloride N-[2-[Bisisopropylamino]-ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxamide HCl N-[2-[di(propan-2-yl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-1,3-thiazole-4-carboxamide,hydrochloride Acotiamide-d6 HCl N-[2-[di(propan-2-yl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoy Acetylformamide hydrochloride Acotiamide dihydrochloride 4-Thiazolecarboxamide, N-[2-[bis(1-methylethyl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-, hydrochloride (1:1) Acotiamide Impurity 14 HCl Acotiamide (hydrochloride) (Acotiamide Impurity) Acotiamide Impurity 20 HCl 185104-11-4 C21H30N4O5SHCl