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2-THIOADENOSINE

2-THIOADENOSINE Structure
CAS No.
43157-50-2
Chemical Name:
2-THIOADENOSINE
Synonyms
2-Thio-Ar;2-THIOADENOSINE;Adenosine Impurity 4;Cangrelor Impurity 6;2,3-dihydro-2-thioxoAdenosine;Adenosine,1,2-dihydro-2-thioxo-;Adenosine, 2,3-dihydro-2-thioxo-;2-Thioadenosine (Cangrelor intermediate 1);6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purine-2-thione;(2R,3R,4S,5R)-2-(6-aMino-2-Mercapto-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol
CBNumber:
CB2267322
Molecular Formula:
C10H13N5O4S
Molecular Weight:
299.31
MOL File:
43157-50-2.mol
Modify Date:
2024/10/10 10:35:21

2-THIOADENOSINE Properties

Melting point >178°C (dec.)
Boiling point 544.5±60.0 °C(Predicted)
Density 2.18±0.1 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
solubility Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form Solid
pka 8.37±0.40(Predicted)
color Pale Yellow to Yellow
CAS DataBase Reference 43157-50-2

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2934999090

2-THIOADENOSINE Chemical Properties,Uses,Production

Description

2-Thioadenosine is a pharmaceutical intermediate compound used in the preparation of cangrelor, a P2Y12 platelet receptor antagonist used to prevent or reduce the risk of thrombosis during stenting procedures. In biology, it regulates the synthesis and degradation of important biomolecules such as DNA, RNA and proteins. It also regulates cell signalling pathways, including those involved in cell growth, proliferation and apoptosis. In addition, it plays a role in maintaining cellular redox balance and regulating oxidative stress.

Uses

2-Thioadenosine has application for developing platelet aggregation inhibitors.

Application

Intermediate in the synthesis of cangrelor

2-THIOADENOSINE Preparation Products And Raw materials

Global( 148)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Astrix Pharmaceuticals +91-9989993941 +91-9989993941 Hyderabad, India 111 58 Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6700 30 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6739 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6754 58 Inquiry
Shanghai Daken Advanced Materials Co.,Ltd +86-371-+86-371-66670886 China 19805 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21628 55 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29858 58 Inquiry
Shenzhen Nexconn Pharmatechs Ltd +86-755-89396905 +86-15013857715 China 10406 58 Inquiry
(2R,3R,4S,5R)-2-(6-aMino-2-Mercapto-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol Adenosine,1,2-dihydro-2-thioxo- Cangrelor Impurity 6 6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purine-2-thione 2,3-dihydro-2-thioxoAdenosine 2-THIOADENOSINE 2-Thioadenosine (Cangrelor intermediate 1) 6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purine-2-thione Adenosine Impurity 4 2-Thio-Ar Adenosine, 2,3-dihydro-2-thioxo- 6-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purine-2-thione 43157-50-2