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2'-O-Methylguanosine

CAS No.: 2140-71-8

Chemical Name:: 2'-O-Methylguanosine

Synonyms: 2'-OMe-G;2'-OMe-G;2'-OMe-Gr;2'-OMe-rG;2'-OMe-Gr;2'-OMe Guanosine;2'-OMe Guanosine;2'-O-METHYLGUANOSINE;2'-O-Methylguanosine;2 '- Methoxyguanosine

CBNumber:: CB2276641

Molecular Formula:: C11H15N5O5

Molecular Weight:: 297.27

MOL File:: 2140-71-8.mol

MSDS File:: SDS

Modify Date:: 2024/8/28 13:53:22

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2'-O-Methylguanosine Properties

Melting point	227-231°C (dec.)
Density	1.98±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	Aqueous Base (Slightly), DMSO (Slightly),
pka	9?+-.0.20(Predicted)
form	Powder
color	White to Off-white
λmax	256 (pH 1)；258 (pH 11)
InChI	InChI=1S/C11H15N5O5/c1-20-7-6(18)4(2-17)21-10(7)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,7-,10-/m1/s1
InChIKey	OVYNGSFVYRPRCG-KQYNXXCUSA-N
SMILES	OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N=C2)[C@H](OC)[C@@H]1O
CAS DataBase Reference	2140-71-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes

Risk Statements

36/37/38-22

Safety Statements

26-36-60-36/37

HS Code

29349990

NFPA 704

	0
2		0

2'-O-Methylguanosine price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemicals (India)	M2318	2'-O-Methylguanosine	2140-71-8	200MG	₹5200	2022-05-26	Buy
TCI Chemicals (India)	M2318	2'-O-Methylguanosine	2140-71-8	1G	₹20800	2022-05-26	Buy

Product number	Packaging	Price	Buy
M2318	200MG	₹5200	Buy
M2318	1G	₹20800	Buy

2'-O-Methylguanosine Chemical Properties,Uses,Production

Description

2''-O-Methylguanosine is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase, using S-adenosyl-L-methionine (Item Nos. 16376 | 13956) as a substrate. Through its interaction with other modified nucleosides, 2''-O-methylguanosine is thought to stabilize the structure of the tRNA. 2''-O-Methylguanosine can also be found in rRNA. Normal and modified nucleosides, including 2''-O-methylguanosine, have been shown to be secreted by a natural suppressor cell line and induce apoptosis in K562/Molt4 target cells.

Chemical Properties

White Solid

Definition

ChEBI: Guanosine with the hydrogen on the hydroxyl at position C-2' substituted with a methyl group.

Synthesis

8-Thio-2'-O-methylguanosine (1 mmole) is dissolved in water and the solution is heated at reflux with Raney nickel for 6 h. The product is isolated by passing the solution through a short pad of celite and is further crystallizing to afford 2'-O-methylguanosine.

2'-O-Methylguanosine Preparation Products And Raw materials

Raw materials

Preparation Products

2'-O-Methylguanosine Suppliers

Global( 255)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
ChemGenes India Pvt Ltd	+91-8687421036 +91-8687421036	Uttar Pradesh, India	16	58	Inquiry
Chemgenes India Pvt. Ltd.	+91 (522) 656-7939	New Delhi, India	54	50	Inquiry
Chem Genes India Private Limited	08048372510Ext 250	Uttar Pradesh, India	16	58	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6707	30	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6778	58	Inquiry
APAC Sourcing Solutions Ltd.	91-124-4007103	Haryana, India	61	58	Inquiry
Maas Pharma Chemicals	+91-9958666224	Delhi, India	1607	58	Inquiry
Wuhu Nuowei chemistry Co., Ltd.	+86-0553-2911116-802 +undefined17756524438	China	1640	58	Inquiry
Yunbio Tech Co.,Ltd.	+86-010-60605551 +86-18046518538	China	321	58	Inquiry

Supplier	Advantage
ChemGenes India Pvt Ltd	58
Chemgenes India Pvt. Ltd.	50
Chem Genes India Private Limited	58
CHEMSWORTH	30
A.J Chemicals	58
TCI Chemicals (India) Pvt. Ltd.	58
APAC Sourcing Solutions Ltd.	58
Maas Pharma Chemicals	58
Wuhu Nuowei chemistry Co., Ltd.	58
Yunbio Tech Co.,Ltd.	58

2'-O-Methylguanosine Spectrum

2'-O-Methylguanosine(2140-71-8)¹HNMR

2140-71-8(2'-O-Methylguanosine)Related Search:

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2'-OMe-G 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]-3H-purin-6-one 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-3H-purin-6-one 2-azanyl-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-oxolan-2-yl]-3H-purin-6-one 2'-OMe Guanosine 2'-O-METHYLGUANOSINE 2'-O-Methyl-D-guanosine 2'-O-Methyl Guanosine, >=99% 2-aMino-9-[(2R,3R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)-3-Methoxyoxolan-2-yl]-6,9-dihydro-1H-purin-6-one 2'-O-Methylguanosine Hydrate 2'-OMe-Gr 2'-O-MethylguanosineHydrate> Guanosine, 2'-O-methyl- 2'-OMe-rG 2'-O-Methylguanosine USP/EP/BP 2-Amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-1H-purin-6(9H)-one 2’-O-Methylguanosine,RNA modified nucleoside Gm Apoptosis,2’ OMe Guanosine,rRNA,inhibit,2’OMeGuanosine,Inhibitor,Nucleoside Antimetabolite/Analog,tRNA 2 '- Methoxyguanosine 2'-O-Methylguanosine 2'-OMe Guanosine 2'-OMe-G 2'-OMe-Gr 2140-71-8 C11H15N5O5xH2O C11H15N5O5H2O Nucleotides Bases & Related Reagents Carbohydrates & Derivatives Heterocycles Nucleosides Modified（deoxy）nucleoside Nucleosides-2'-OMe Nucleosides