ChemicalBook > Product Catalog >Biochemical Engineering >Nucleoside drugs >Nucleotides and their analogs >Guanosine
Guanosine
- CAS No.
- 118-00-3
- Chemical Name:
- Guanosine
- Synonyms
- GR;2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one;VERNINE;2-AMINO-9-BETA-D-RIBOFURANOSYL-9H-PURINE-6-(1H)-ONE;2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one;Guo;GCCR;Guanyin;Guanozin;uanosine
- CBNumber:
- CB2701721
- Molecular Formula:
- C10H13N5O5
- Molecular Weight:
- 283.24
- MOL File:
- 118-00-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/1/27 9:38:02
| Melting point | 250 °C (dec.) (lit.) |
|---|---|
| alpha | -62 º (c=3, in 0.1 N NaOH) |
| Boiling point | 425.8°C (rough estimate) |
| Density | 1.3790 (rough estimate) |
| refractive index | -76 ° (C=1, 1mol/L NaOH) |
| storage temp. | room temp |
| solubility | 0.1 M NaOH: 0.1 g/mL, clear, slightly yellow |
| pka | pK1:1.9(＋1);pK2:9.25(0);pK3:12.33(OH) (25°C) |
| form | Powder |
| color | White to light yellow |
| Odor | Odorless |
| PH | 2.14；9.03 |
| optical activity | [α]20/D -73±2°, c = 1.5% in 1 M NaOH |
| biological source | synthetic |
| Water Solubility | 0.75 g/L (25 ºC) |
| λmax | 256 (pH 0.7)；253，276 (pH 7)；256～266 (pH 11.3) |
| Merck | 14,4566 |
| BRN | 625911 |
| InChIKey | NYHBQMYGNKIUIF-UUOKFMHZSA-N |
| LogP | -2.331 (est) |
| CAS DataBase Reference | 118-00-3(CAS DataBase Reference) |
| NIST Chemistry Reference | guanosine(118-00-3) |
| EPA Substance Registry System | Guanosine (118-00-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P301+P310 | |||||||||
| Hazard Codes | T,Xi | |||||||||
| Risk Statements | 25 | |||||||||
| Safety Statements | 45-24/25-23 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | MF8750000 | |||||||||
| F | 10-23 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | Ⅲ | |||||||||
| HS Code | 29349990 | |||||||||
| NFPA 704 |
|
Guanosine price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | G6752 | Guanosine ≥98% | 118-00-3 | 1G | ₹4449.08 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G6752 | Guanosine ≥98% | 118-00-3 | 25G | ₹7599.15 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G6752 | Guanosine ≥98% | 118-00-3 | 100G | ₹11875.03 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G6752 | Guanosine ≥98% | 118-00-3 | 500G | ₹36675.1 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G6264 | Guanosine suitable for cell culture, BioReagent | 118-00-3 | 1G | ₹2727.9 | 2022-06-14 | Buy |
Guanosine Chemical Properties,Uses,Production
Description
Guanosine is a purine nucleoside that is comprised of the purine base guanine attached to a ribose moiety. Mono-, di-, tri-, and cyclic monophosphorylated forms of guanosine (GMP, GDP, GTP, and cGMP, respectively) are essential for a variety of endogenous biochemical processes, such as signal transduction, metabolism, and RNA synthesis.
Chemical Properties
White, crystalline powder; odorless; mild saline taste. Very slightly soluble in cold water; soluble in boiling water, dilute mineral acids, hot acetic acid, and dilute bases; insoluble in alcohol, ether, chloroform, and benzene.
Uses
Guanosine is used as a constituent of nucleic acids. It is used in metallic paints, simulated pearls,plastics,cosmetics industry etc,. It has been also used in pharmacokinetics as a prodrug. Guanosine is used in cell culture applications as a precursor of GMP.
Definition
ChEBI: A purine nucleoside in which guanine is attached to ribofuranose via a beta-N9-glycosidic bond.
General Description
Guanosine is an aromatic organic molecule and a purine nucleoside. It is present in the cerebrospinal fluid, intestinal cells, blood-brain barrier and in brain microvessels.
Purification Methods
It crystallises from water as a dihydrate. Dry it at 110o.[Beilstein 26/18 V 81.]
Guanosine Preparation Products And Raw materials
Raw materials
Preparation Products
Ribavirin
N2,9-Diacetylguanine
Calcium 5'-ribonucleotide
Guanosine 5'-monophosphate disodium salt
5'-Guanylic acid
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Global( 751)Suppliers
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|---|---|---|---|---|---|
| ARRAKIS INDUSTRIES LLP | +91 74995 32711 | Maharashtra, India | 1353 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
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| Triveni chemicals | 08048762458 | New Delhi, India | 6088 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| ARRAKIS INDUSTRIES LLP | 58 |
| JSK Chemicals | 58 |
| Molychem | 58 |
| HiMedia Laboratories | 58 |
| CHEMSWORTH | 30 |
| Scientific OEM | 38 |
| ALPHA CHEMIKA | 43 |
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| Triveni chemicals | 58 |
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- Oct 21，2024
118-00-3(Guanosine)Related Search:
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O-(BETA-D-RIBOFURANOSYL)GUANINE
D-GUANOSINE
GUANOSINE
GUANINE-9-BETA-D-RIBOFURANOSIDE
GUANINE RIBOSIDE
9-[BETA-D-RIBOFURANOSYL]GUANINE
9-B-D-RIBOFURANOSYLGUANINE
9-(β-D-Ribofuranosyl)guanine
guanosine cell culture tested
Guanosine Guanine 9-B-D-ribofuranoside
guanosine minimum 99%
GUANOSINE CELL CULTURE REAGENT 97-103% USP
GUANOSINE ULTRA PURE 98+%
Guanine-9-β-D-ribof
GuanosineForBiochemistry
Guanosine, 98+%
2-AMINO-9-BETA-D-RIBOFURANOSYL-9H-PURINE-6-(1H)-ONE (GUANOSINE)
2-Amino-9-β-D-ribofuranosyl-[9H]-purine-6-[1H]-one
GUANOSINE,REAGENT
2-Amino-9-beta-D-ribofuranosyl-9H-purine-6-(1H)-one hydrate
Guanine-9-beta-ribofuranoside
GUANOSINE extrapure
9-(β-D-Ribofuranosyl)guanine, Guanine-9-β-D-ribofuranoside
2-Amino-9-(β-D-ribofuranosyl)-9H-purin-6(1H)-one
Guanosine,99%
2-aMino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
2-aMino-9-β-d-ribofuranosyl-9h-purine-6-(1h)-one hydrate
[1',2',3',4',5'-13C5]guanosine Mono-hydrate
[2'-2H]guanosine Monohydrate
[3'-2H]guanosine Monohydrate
GCCR
Guanosine Vetec(TM) reagent grade, >=98%
2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxy-methyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-
Guanosine, Low endotoxin: ≤ 0.5 EU/mgGrade 1,
≥ 99% (HPLC)
Guanine riboside Guanine riboside
2(3H)-Imino-9-beta-D-ribofuranosyl-9H-purin-6(1H)-one
2-Amino-1,9-dihydro-9beta-d-ribofuranosyl-6H-purin-6-one
2-amino-inosin
6H-Purin-6-one, 2-amino-1,9-dihydro-9-beta-d-ribofuranosyl-
9-beta-d-ribofuranosyl-guanin
beta-d-Ribofuranoside, guanine-9
Guanine, 9beta-d-ribofuranosyl-
guanine-9,beta-d-ribofuranosid
Guanozin
Guo
Inosine, 2-amino-
Ribofuranoside, guanine-9, beta-D-
USAF cb-11
Adenosine EP Impurity H
uanosine
Adenosine Impurity 8（Adenosine EP Impurity H）（Guanosine）
2-Amino-9-beta-D-ribofuranosyl-1,9-
Guanosine Guanosine
Guanosine>
Guanosine, 98%, for bio
DL-Guanosine
2-Amino-9-beta-D-ribofuranosyl-9H-purine-6-(1H)-one hydrat