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Purine

Purine Structure
CAS No.
120-73-0
Chemical Name:
Purine
Synonyms
9H-PURINE;1H-Purine;7H-Purine;X 128;PURINE;NSC 753;Isopurine;Purine 98%;Purine,99%;Purine,>98%
CBNumber:
CB6447322
Molecular Formula:
C5H4N4
Molecular Weight:
120.11
MOL File:
120-73-0.mol
MSDS File:
SDS
Modify Date:
2024/7/24 15:56:12

Purine Properties

Melting point 214-217 °C (lit.)
Boiling point 214.09°C (rough estimate)
Density 1.3106 (rough estimate)
refractive index 1.7380 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Crystals
pka 2.3(at 20℃)
color White
Water Solubility 400 g/L (20 ºC)
Merck 7942
BRN 3200
CAS DataBase Reference 120-73-0(CAS DataBase Reference)
NIST Chemistry Reference 9H-Purine(120-73-0)
EPA Substance Registry System Purine (120-73-0)

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3
RTECS  UO7450000
HS Code  29335995
Toxicity LD50 intraperitoneal in rat: 800mg/kg
NFPA 704
0
1 0

Purine price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) P55805 Purine 98% 120-73-0 1G ₹29119.25 2022-06-14 Buy
ottokemi P 2707 Purine 98% 120-73-0 100mg ₹3402 2022-05-26 Buy
ottokemi P 2707 Purine 98% 120-73-0 1gm ₹18909 2022-05-26 Buy
ottokemi P 2707 Purine 98% 120-73-0 5gm ₹63009 2022-05-26 Buy
ottokemi P 2707 Purine 98% 120-73-0 10gm ₹96039 2022-05-26 Buy
Product number Packaging Price Buy
P55805 1G ₹29119.25 Buy
P 2707 100mg ₹3402 Buy
P 2707 1gm ₹18909 Buy
P 2707 5gm ₹63009 Buy
P 2707 10gm ₹96039 Buy

Purine Chemical Properties,Uses,Production

Chemical Properties

very slightly yellow to cream crystalline powder

Uses

Organic synthesis, metabolism, and biochemi- cal research. (2) One of a number of basic compounds found in living matter and having a purine-type molecular structure.

Definition

ChEBI: The 9H-tautomer of purine.

Biosynthesis

Basically, the same pathway is found in all organisms capable of purine biosynthesis de novo. The initial substrate is the highly phosphorylated sugar 5-phosphoribosyl-α-1-pyrophosphate (PRPP). An amino group is transferred from glutamine to PRPP catalyzed by the enzyme glutamine PRPP amidotransferase. After that, it takes four reactions to complete the imidazole ring and an additional five reactions to synthesize the pyrimidine moiety and thereby to complete the purine molecule. In some bacteria (e.g., B. subtilis and Escherichia coli), the third step is also catalyzed by a second enzyme (purT) that uses formate instead of a tetrahydrofolic acid derivative as formyl donor. The sixth step has been found to be a two-step reaction, which in some organisms is catalyzed by a single enzyme. The end product of the de novo purine biosynthetic pathway is IMP. After the formation of IMP, purine synthesis splits into two separate pathways leading to the synthesis of AMP and GMP. The control point for feedback inhibition by purine nucleotides and activation by PRPP is on the activity of the first enzyme of the pathway glutamine PRPP amidotransferase. The branching from IMP is regulated by ATP and GTP to ensure a proper balance between ATP and GTP.

General Description

Purine is a heterocyclic organic compound constituting a pyrimidine ring fused to an imidazole ring.

Purification Methods

It crystallises from toluene or EtOH, and sublimes at 100-150o/0.1mm or 160o/10-4mm. The picrate has m 207-209o after crystallisation from 20volumes of H2O. [Beilstein 26 H 354, 26 III/IV 1736.]

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3,5,7-Triazaindole 6H-Imidazo[4,5-d]pyrimidine beta-Purine Imidazo(4,5-d)pyrimidine Isopurine NSC 753 X 128 PURINE TIMTEC-BB SBB004288 7H-IMIDAZO[4,5-D]PYRIMIDINE Purine,>98% 1H-Purine (9CI) imidazolopyrimidine 3H-imidazo[4,5-d]pyrimidine Purine free base Purine 98% FINE ORGANIC COMPOUND PURINE DERIVATIVE Purine,99% Purine, 99% 1GR Purine Solution Purine USP/EP/BP 1H-Purine 7H-Purine 9H-PURINE Purine (6CI, 8CI) 120-73-0 BioChemical Biochemicals and Reagents Building Blocks Nucleosides, Nucleotides, Oligonucleotides Purines Heterocyclic Building Blocks Nucleosides PYRIMIDINE Nucleic acids Heterocycles series Purine