Melamine
- CAS No.
- 108-78-1
- Chemical Name:
- Melamine
- Synonyms
- 1,3,5-Triazine-2,4,6-triamine;Aero;Cymel;Triaminotriazine;Melamin;trimeric cyanamide;2,4,6-Triamino-s-triazine;2,4,6-Triamino-1,3,5-triazine;1,3,5-Triazine-2,4,6-triamine (Melamine);Teoharn
- CBNumber:
- CB6324023
- Molecular Formula:
- C3H6N6
- Molecular Weight:
- 126.12
- MOL File:
- 108-78-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/6 9:21:59
| Melting point | >300 °C (lit.) |
|---|---|
| Boiling point | 224.22°C (rough estimate) |
| Density | 1.573 |
| vapor pressure | 66.65 hPa (315 °C) |
| refractive index | 1.872 |
| Flash point | >110°C |
| storage temp. | no restrictions. |
| solubility | water: soluble25mg/mL, clear to slightly hazy, colorless |
| form | Fine Crystalline Powder |
| pka | 5(at 25℃) |
| color | White |
| PH | 7-8 (32g/l, H2O, 20℃) |
| Water Solubility | 3 g/L (20 ºC) |
| Merck | 14,5811 |
| BRN | 124341 |
| Stability | Stable. Incompatible with strong acids, strong oxidizing agents. Nonflammable. |
| InChIKey | JDSHMPZPIAZGSV-UHFFFAOYSA-N |
| LogP | -1.22 at 20℃ |
| CAS DataBase Reference | 108-78-1(CAS DataBase Reference) |
| IARC | 2B (Vol. Sup 7, 73, 119) 2019 |
| NIST Chemistry Reference | 1,3,5-Triazine-2,4,6-triamine(108-78-1) |
| EPA Substance Registry System | Melamine (108-78-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H361f | |||||||||
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 43-44-20/21 | |||||||||
| Safety Statements | 36/37 | |||||||||
| RIDADR | 3263 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | OS0700000 | |||||||||
| Autoignition Temperature | >600 °C | |||||||||
| TSCA | Yes | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29336980 | |||||||||
| Toxicity | LD50 orally in Rabbit: 3161 mg/kg LD50 dermal Rabbit > 1000 mg/kg | |||||||||
| NFPA 704 |
|
Melamine price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | M2659 | Melamine 99% | 108-78-1 | 1KG | ₹1980.98 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M2659 | Melamine 99% | 108-78-1 | 5G | ₹3117.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M2659 | Melamine 99% | 108-78-1 | 100G | ₹3399.05 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1274 | Melamine Pharmaceutical Secondary Standard; Certified Reference Material | 108-78-1 | 1G | ₹8042.98 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M2659 | Melamine 99% | 108-78-1 | 3KG | ₹5271.78 | 2022-06-14 | Buy |
Melamine Chemical Properties,Uses,Production
Description
Melamine-formaldehyde resin (MFR) is an active ingredient of strong (reinforced) plasters. Sensitization was reported in a plaster-room technician, who applied resin-reinforced pIaster casts, and in dental technicians. MFR was contained in a strong dental pIaster used for mouldings. Used as a textile finish res in, it was also found to be an allergen in a women who replaced clothes in a store. MFR also releases formaldehyde, which may be the sensitizer.
Chemical Properties
Melamine is a white solid organic compound whose molecules consist of a sixmembered heterocyclic ring of alternate carbon and nitrogen atoms with three amino groups attached to the carbons. Condensation polymerization with methanal or other aldehydes produces melamine resins, which are important thermosetting plastics.
Uses
It is used to make high-pressure laminating resins (e.g., decorative countertops), molded compounds (e.g., dinnerware), and surface coating resins (e.g., appliance finishes and automotive topcoats). Additional major products are textile and paper treatment resins. Miscellaneous uses include adhesive resins for gluing lumber, plywood, and flooring, and resins for leather tanning agents. Melamine, melamine cyanurate, other melamine salts, and guanidine compounds are currently the most used group of nitrogencontaining flame retardants. Melamine is used as a flame retardant additive for polypropylene and polyethylene. Melamine cyanurate is employed commercially as a flame retardant for polyamides and terephthalates.
Production Methods
Melamine is prepared almost exclusively by the urea process—the action of ammonia on urea. It is produced worldwide.
Preparation
The standard route to melamine is from urea. Urea is
heated in the presence of ammonia at 250-350??C and 4--20 MPa. The
reaction probably involves the simultaneous dehydration and hydration of
urea to form cyanamide and ammonium carbamate; trimerization of the
cyanamide then leads to melamine:
Thus only 50% of the urea used gives melamine in one step and ammonium carbamate has to be separated and converted to urea for recycling. Despite this limitation, the urea route is the most economical of currently available routes.
General Description
Colorless to white monoclinic crystals or prisms or white powder. Sublimes when gently heated.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Melamine is incompatible with strong oxidizing agents and strong acids . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Hazard
Toxic by ingestion, skin, and eye irritant. Questionable carcinogen.
Fire Hazard
Literature sources indicate that Melamine is nonflammable.
Contact allergens
Melamine-formaldehyde resin (MFR) results from condensation of melamine and formaldehyde. It is anactive ingredient of strong (reinforced) plasters, such as industrial or some dental plasters used for molding.It is also used as a textile finish resin. MFR acts as an allergen generally because of formaldehyde releasing (see Chap. 40)
Safety Profile
Moderately toxic by ingestion and intraperitoneal routes. An eye, skin, and mucous membrane irritant. Causes dermatitis in humans. Questionable carcinogen with experimental carcinogenic and tumorigenic data. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and CN-.
Potential Exposure
Manufactured from urea, melamine is used in the manufacture of plastics, melamineformaldehyde resins; rubber, synthetic textiles; laminates, adhesives, and molding compound
Carcinogenicity
A bioassay of melamine was conducted in rats and mice by NTP. Male F344 rats and B6C3F1 mice were administered melamine in their diets at concentrations of 2250 or 4500 ppm daily for 103 weeks.Female rats were fed 4500 or 9000 ppm melamine. At the end of 111 weeks, surviving animals were killed and examined.
Purification Methods
Crystallise Melamine from water or dilute aqueous NaOH. It sublimes at ~240o on prolonged heating. [Beilstein 26 I 74, 26 II 132, 26 III/IV 1253.]
Incompatibilities
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Melamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents such as hydrides, nitrides, alkali metals, and sulfides.
Melamine Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
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chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Sudarshan Pharma Industries Limited | +91-2242221111 +91-9320932107 | Maharashtra, India | 37 | 58 | Inquiry |
| SynThink RESEARCH CHEMICALS | +91-8177860948 +91-8177860948 | Mumbai, India | 494 | 58 | Inquiry |
| Soham Chemical Industries | +91-7016081644 +91-7016081644 | Mumbai, India | 83 | 58 | Inquiry |
| GLP Pharma Standards | +91 9866074638 | Hyderabad, India | 1644 | 58 | Inquiry |
| Reenold Enterprises | +91-8208173540 +91-8208173540 | Maharashtra, India | 28 | 58 | Inquiry |
| UNILOSA INTERNATINAL PRIVATE LIMITED | +91-9999069917 +91-9999069917 | New Delhi, India | 152 | 58 | Inquiry |
| Varanous Labs Pvt Ltd | +91-7036248882 +91-7036248882 | Hyderabad, India | 1541 | 58 | Inquiry |
| Gujarat State Fertilizers And Chemicals Ltd | +91-2652242451 +91-9879275045 | Gujarat, India | 21 | 58 | Inquiry |
| Orgamine Chemicals(I) Pvt Ltd | +91-9820080281 +91-9820080281 | Maharashtra, India | 451 | 58 | Inquiry |
| Chem stride | +91-8169461298 +91-8169461298 | Maharashtra, India | 27 | 58 | Inquiry |
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