ChemicalBook > Product Catalog >Biochemical Engineering >Nucleoside drugs >Nucleotides and their analogs >5-METHYLCYTOSINE

5-METHYLCYTOSINE

CAS No.: 554-01-8

Chemical Name:: 5-METHYLCYTOSINE

Synonyms: 4-Amino-5-methylpyrimidin-2(1H)-one;5-methylcytosin;5-METHYLCYTOSINE;Cytosine, 5-methyl-;5-Methylcytosine,>96%;5-Methylcytosine (~90%);5-Methylcytosine, 97%, 97%;5-METHYLCYTOSINE USP/EP/BP;4-Amino-5-methyl-2-pyrimidinol;4-amino-5-methyl-3H-pyrimidin-2-one

CBNumber:: CB5154906

Molecular Formula:: C5H7N3O

Molecular Weight:: 125.13

MOL File:: 554-01-8.mol

MSDS File:: SDS

Modify Date:: 2024/2/6 18:17:50

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5-METHYLCYTOSINE Properties

Melting point	270°C (rough estimate)
Boiling point	232.57°C (rough estimate)
Density	1.2602 (rough estimate)
refractive index	1.6510 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Methanol (Sparingly, Heated)
pka	9.05±0.10(Predicted)
form	Crystalline
color	White to Off-White
Water Solubility	Soluble in water.
Merck	14,6050
CAS DataBase Reference	554-01-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H319-H317

Precautionary statements

P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P280-P305+P351+P338-P337+P313P

RTECS

UW7362350

NFPA 704

	1
0		0

5-METHYLCYTOSINE Chemical Properties,Uses,Production

Chemical Properties

Crystals in prisms from water.

Uses

5-Methylcytosine is used as a marker to protect DNA from being cut by native methylation-sensitive restriction enzymes. It is also employed in the production of 4-amino-5-hydroxy-5-methyl-2-oxo-2,5-dihydro-imidazole-1-carbaldehyde.

Definition

ChEBI: A pyrimidine that is a derivative of cytosine, having a methyl group at the 5-position.

Purification Methods

Crystallise it from water (solubility is 3.4%). The hydrochloride has m 299-301o (sintering at 280o) (from aqueous HCl/Me2CO). [Hitchings et al. J Biol Chem 177 537 1949, Cohn J Am Chem Soc 73 1539 1951, Beilstein 25 II 183, 25 III/IV 3727.]

5-METHYLCYTOSINE Preparation Products And Raw materials

Raw materials

5-METHYL-2-THIOCYTOSINE 5-methyl-4-(1,2,4-triazol-1-yl)-pyrimidin-2-(1H)-one 2-(Ethylthio)-5-methyl-4-pyrimidinamine 2(1H)-Pyrimidinone, 4-methoxy-5-methyl- (8CI,9CI) 4-chloro-2-ethylsulfanyl-5-methyl-pyrimidine

5-Methyl-2'-deoxycytidine 5-HydroxyMethyl cytidine 5-(Hydroxymethyl)-2'-deoxycytidine 5-HYDROXYMETHYLCYTOSINE (5-methyl)dithiouracil

5-formyl-2'-deoxycytidine 5-METHYLCYTIDINE Ethanol Thymine

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Preparation Products

1-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

5-METHYLCYTOSINE Suppliers

Global( 228)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
JSK Chemicals	+919879767970	Gujarat, India	3756	58	Inquiry
Otto Chemie Pvt. Ltd.	+91 9820041841	Mumbai, India	5873	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Chongqing Zhihe Biopharmaceutical Co., Ltd.	+86-18580541567 +86-17782035140	China	326	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29901	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	China	12915	58	Inquiry
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	China	34571	58	Inquiry

Supplier	Advantage
JSK Chemicals	58
Otto Chemie Pvt. Ltd.	58
CLEARSYNTH LABS LTD.	58
A.J Chemicals	58
Chongqing Zhihe Biopharmaceutical Co., Ltd.	58
career henan chemical co	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Zhengzhou Alfa Chemical Co.,Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

5-METHYLCYTOSINE Spectrum

5-METHYLCYTOSINE(554-01-8)¹HNMR

554-01-8(5-METHYLCYTOSINE)Related Search:

5'-O-(4,4'-DIMETHOXYTRITYL)-5-METHYL-N4-BENZOYL-2'-DEOXYCYTIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE 5-METHYLCYTIDINE 5-(TRIFLUOROMETHYL)-2'-DEOXYCYTIDINE 5-CARBOXYCYTOSINE 5-METHYLCYTOSINE

1-(2-Deoxy-beta-D-ribofuranosyl)-5-methylcytosine 2'-C-Methylcytidine 2-O-Methylcytosine 5-METHYLCYTOSINE HCL,5-METHYLCYTOSINE HYDROCHLORIDE 98%,5-METHYLCYTOSINE HYDROCHLORIDE,5-Methylcytosine hydrochloride ,98% 5-HYDROXYMETHYLCYTOSINE

N4-Methylcytosine ,98%,N4-Methylcytosine Cytosine FLUORESCEIN-12-DCTP BIOTIN-11-DDCTP N4-BENZOYL-5-METHYLDEOXYCYTIDINE

5'-METHYL-2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE TRILITHIUM SALT 5'-O-(4,4'-DIMETHOXYTRITYL)-N4-BENZOYL-5-METHYL-2'-DEOXYCYTIDINE 3-METHYLCYTOSINE HYDROCHLORIDE

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4-Amino-5-methyl-2-pyrimidinol Cytosine, 5-methyl- 5-Methylcytosine,>96% 2(1H)-Pyrimidinone, 4-amino-5-methyl- (9CI) 4-amino-5-methyl-3H-pyrimidin-2-one 2(1H)-Pyrimidinone, 6-amino-5-methyl- 2(1H)-Oxo-4(3H)-imino-5-methylpyrimidine 2(1H)-Oxo-4-amino-5-methylpyrimidine 2-Hydroxy-4-amino-5-methylpyrimidine 4-Amino-5-methyl-1,2-dihydropyrimidine-2-one 4(6)-AMino-2-hydroxy-5-MethylpyriMidine 4-AMino-5-Methyl-2(1H)pyriMidinone 4-aMino-5-Methyl-1,2-dihydropyriMidin-2-one 5-Methylcytosine, 97%, 97% 5-METHYLCYTOSINE 5-methylcytosin 5-Methylcytosine (~90%) 5-METHYLCYTOSINE USP/EP/BP 4-Amino-5-methylpyrimidin-2(1H)-one 554-01-8 Nucleic acids Pyrimidines PYRIMIDINE Elisa Kit-Rat Elisa Kit