ChemicalBook > Product Catalog >Biochemical Engineering >Nucleoside drugs >Nucleotides and their analogs >5-METHYLCYTOSINE

5-METHYLCYTOSINE

CAS No.: 554-01-8

Chemical Name:: 5-METHYLCYTOSINE

Synonyms: 4-Amino-5-methylpyrimidin-2(1H)-one;5-methylcytosin;5-METHYLCYTOSINE;Cytosine, 5-methyl-;5-Methylcytosine,>96%;5-Methylcytosine (~90%);5-Methylcytosine, 97%, 97%;5-METHYLCYTOSINE USP/EP/BP;4-Amino-5-methyl-2-pyrimidinol;5-Methylcytosine, 10 mM in DMSO

CBNumber:: CB5154906

Molecular Formula:: C5H7N3O

Molecular Weight:: 125.13

MOL File:: 554-01-8.mol

MSDS File:: SDS

Modify Date:: 2025/4/17 18:22:24

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5-METHYLCYTOSINE Properties

Melting point	270°C (rough estimate)
Boiling point	232.57°C (rough estimate)
Density	1.2602 (rough estimate)
refractive index	1.6510 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Methanol (Sparingly, Heated)
pka	9.05±0.10(Predicted)
form	Crystalline
color	White to Off-White
Water Solubility	Soluble in water.
Merck	14,6050
CAS DataBase Reference	554-01-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H319-H317

Precautionary statements

P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P280-P305+P351+P338-P337+P313P

RTECS

UW7362350

NFPA 704

	1
0		0

5-METHYLCYTOSINE Chemical Properties,Uses,Production

Chemical Properties

Crystals in prisms from water.

Uses

5-Methylcytosine is used as a marker to protect DNA from being cut by native methylation-sensitive restriction enzymes. It is also employed in the production of 4-amino-5-hydroxy-5-methyl-2-oxo-2,5-dihydro-imidazole-1-carbaldehyde.

Definition

ChEBI: A pyrimidine that is a derivative of cytosine, having a methyl group at the 5-position.

Purification Methods

Crystallise it from water (solubility is 3.4%). The hydrochloride has m 299-301o (sintering at 280o) (from aqueous HCl/Me2CO). [Hitchings et al. J Biol Chem 177 537 1949, Cohn J Am Chem Soc 73 1539 1951, Beilstein 25 II 183, 25 III/IV 3727.]

5-METHYLCYTOSINE Preparation Products And Raw materials

Raw materials

5-METHYL-2-THIOCYTOSINE 5-methyl-4-(1,2,4-triazol-1-yl)-pyrimidin-2-(1H)-one 2-(Ethylthio)-5-methyl-4-pyrimidinamine 2(1H)-Pyrimidinone, 4-methoxy-5-methyl- (8CI,9CI) 4-chloro-2-ethylsulfanyl-5-methyl-pyrimidine

5-Methyl-2'-deoxycytidine 5-HydroxyMethyl cytidine 5-(Hydroxymethyl)-2'-deoxycytidine 5-HYDROXYMETHYLCYTOSINE (5-methyl)dithiouracil

5-formyl-2'-deoxycytidine 5-Methylcytidine Ethanol Thymine

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Preparation Products

1-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

5-METHYLCYTOSINE Suppliers

Global( 239)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
JSK Chemicals	+919879767970	Gujarat, India	3756	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6257	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6100	58	Inquiry
Otto Chemie Pvt. Ltd.	+91 9820041841	Mumbai, India	5870	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29858	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49732	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	32159	58	Inquiry
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	China	34563	58	Inquiry
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	China	23541	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	22854	58	Inquiry

Supplier	Advantage
JSK Chemicals	58
CLEARSYNTH LABS LTD.	58
A.J Chemicals	58
Otto Chemie Pvt. Ltd.	58
career henan chemical co	58
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
ANHUI WITOP BIOTECH CO., LTD	58
Dideu Industries Group Limited	58

5-METHYLCYTOSINE Spectrum

5-METHYLCYTOSINE(554-01-8)¹HNMR

554-01-8(5-METHYLCYTOSINE)Related Search:

5'-O-(4,4'-DIMETHOXYTRITYL)-5-METHYL-N4-BENZOYL-2'-DEOXYCYTIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE 5-(TRIFLUOROMETHYL)-2'-DEOXYCYTIDINE 5-CARBOXYCYTOSINE 5-METHYLCYTOSINE 1-(2-Deoxy-beta-D-ribofuranosyl)-5-methylcytosine

2'-C-Methylcytidine 2-O-Methylcytosine 5-METHYLCYTOSINE HCL,5-METHYLCYTOSINE HYDROCHLORIDE 98%,5-METHYLCYTOSINE HYDROCHLORIDE,5-Methylcytosine hydrochloride ,98% 5-HYDROXYMETHYLCYTOSINE N4-Methylcytosine ,98%,N4-Methylcytosine

Cytosine 5-Methylcytidine FLUORESCEIN-12-DCTP BIOTIN-11-DDCTP 5'-O-(4,4'-DIMETHOXYTRITYL)-N4-BENZOYL-5-METHYL-2'-DEOXYCYTIDINE

5'-METHYL-2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE TRILITHIUM SALT N4-BENZOYL-5-METHYLDEOXYCYTIDINE 3-METHYLCYTOSINE HYDROCHLORIDE

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4-Amino-5-methyl-2-pyrimidinol Cytosine, 5-methyl- 5-Methylcytosine,>96% 2(1H)-Pyrimidinone, 4-amino-5-methyl- (9CI) 4-amino-5-methyl-3H-pyrimidin-2-one 2(1H)-Pyrimidinone, 6-amino-5-methyl- 2(1H)-Oxo-4(3H)-imino-5-methylpyrimidine 2(1H)-Oxo-4-amino-5-methylpyrimidine 2-Hydroxy-4-amino-5-methylpyrimidine 4-Amino-5-methyl-1,2-dihydropyrimidine-2-one 4(6)-AMino-2-hydroxy-5-MethylpyriMidine 4-AMino-5-Methyl-2(1H)pyriMidinone 4-aMino-5-Methyl-1,2-dihydropyriMidin-2-one 5-Methylcytosine, 97%, 97% 5-METHYLCYTOSINE 5-methylcytosin 5-Methylcytosine (~90%) 5-METHYLCYTOSINE USP/EP/BP 4-Amino-5-methylpyrimidin-2(1H)-one 5-Methylcytosine, 10 mM in DMSO 554-01-8 Nucleic acids Pyrimidines PYRIMIDINE Elisa Kit-Rat Elisa Kit