5-Methyl-2'-deoxycytidine
- CAS No.
- 838-07-3
- Chemical Name:
- 5-Methyl-2'-deoxycytidine
- Synonyms
- 5-mdC;5-Me-dC;5MedCyd;5-Me-2'-dC;5-METHYL-DC;5-Methyl-2'-deoxycyt;Deoxy methylcytidine;5-methyldeoxycytidine;5-Me-2'-deoxycytidine;2'-Deoxy-5-Me-Cytidine
- CBNumber:
- CB1132913
- Molecular Formula:
- C10H15N3O4
- Molecular Weight:
- 241.24
- MOL File:
- 838-07-3.mol
- Modify Date:
- 2023/6/8 9:02:17
| Melting point | 217-219 °C(lit.) |
|---|---|
| Boiling point | 492.8±55.0 °C(Predicted) |
| Density | 1?+-.0.1 g/cm3(Predicted) |
| refractive index | 44 ° (C=1.4, H2O) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated), Water (Slightly) |
| form | Powder |
| pka | pK1:4.33 (25°C) |
| color | White to Off-white |
| Water Solubility | Soluble in water. |
| Stability | Hygroscopic |
| CAS DataBase Reference | 838-07-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | HA3860000 | |||||||||
| HS Code | 29389090 | |||||||||
| NFPA 704 |
|
5-Methyl-2'-deoxycytidine price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemicals (India) | D3610 | 2'-Deoxy-5-methylcytidine | 838-07-3 | 100MG | ₹3000 | 2022-05-26 | Buy |
| TCI Chemicals (India) | D3610 | 2'-Deoxy-5-methylcytidine | 838-07-3 | 500MG | ₹11900 | 2022-05-26 | Buy |
| TCI Chemicals (India) | D3610 | 2'-Deoxy-5-methylcytidine | 838-07-3 | 5G | ₹89500 | 2022-05-26 | Buy |
5-Methyl-2'-deoxycytidine Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
5-Methyl-2'-deoxycytidine is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo DNA methylation. It has been used in epigenetics research to investigate the dynamics of DNA methylation pattern in the control of gene expression.
General Description
Giel-Pietraszuk et al. developed a new method for quantification of 5-methyl-2'-deoxycytidine (m5C) in the DNA. The technique is based on the conversion of m5C into fluorescent 3, N4-etheno-5-methyl-2'-deoxycytidine (εm5C) and its identification by reversed-phase high-performance liquid chromatography (RP-HPLC)[1].The measurement of 5-meC and 5-medC in urine may help assess changes in DNA methylation status in the whole body and investigate the DNA demethylation mechanism in vivo. 5-MedC was first detected in urine using an inhibition ELISA method;12 however, because ELISA may suffer from poor selectivity and sensitivity, later urinary measurements of 5-medC were developed mainly based on the chromatographic techniques[2].
References
[1] Ma?gorzata Giel-Pietraszuk. “Quantification of 5-methyl-2’-deoxycytidine in the DNA.” Acta biochimica Polonica 62 2 (2015): 281–6.
[2] Chiung-Wen Hu. “Direct Analysis of 5-Methylcytosine and 5-Methyl-2′-deoxycytidine in Human Urine by Isotope Dilution LC-MS/MS: Correlations with N-Methylated Purines and Oxidized DNA Lesions.” Chemical Research in Toxicology 25 2 (2012): 462–470.
5-Methyl-2'-deoxycytidine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Yunbio Tech Co.,Ltd. | +86-010-60605551 +86-18046518538 | China | 321 | 58 | Inquiry |
| NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | China | 9980 | 58 | Inquiry |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 16209 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21669 | 55 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29898 | 58 | Inquiry |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | China | 7353 | 58 | Inquiry |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | China | 6387 | 58 | Inquiry |
838-07-3(5-Methyl-2'-deoxycytidine)Related Search:
1of4
chevron_right